Enantioselective, Palladium-Catalyzed α-Arylation of N-Boc Pyrrolidine: In Situ React IR Spectroscopic Monitoring, Scope, and Synthetic Applications G Barker, JL McGrath, A Klapars, D Stead, G Zhou, KR Campos, ... The Journal of organic chemistry 76 (15), 5936-5953, 2011 | 157 | 2011 |
An Experimental and in Situ IR Spectroscopic Study of the Lithiation–Substitution of N-Boc-2-phenylpyrrolidine and -piperidine: Controlling the Formation of … NS Sheikh, D Leonori, G Barker, JD Firth, KR Campos, AJHM Meijer, ... Journal of the American Chemical Society 134 (11), 5300-5308, 2012 | 117 | 2012 |
Diamine-Free Lithiation−Trapping of N-Boc Heterocycles using s-BuLi in THF G Barker, P O’Brien, KR Campos Organic Letters 12 (18), 4176-4179, 2010 | 106 | 2010 |
Asymmetric Lithiation Trapping of N-Boc Heterocycles at Temperatures above −78 °C G Gelardi, G Barker, P O’Brien, DC Blakemore Organic letters 15 (21), 5424-5427, 2013 | 40 | 2013 |
Asymmetric synthesis via aziridinium ions: exploring the stereospecificity of the ring opening of aziridinium ions and a formal synthesis of (−)-swainsonine SJ Oxenford, SP Moore, G Carbone, G Barker, P O’Brien, MR Shipton, ... Tetrahedron: Asymmetry 21 (11-12), 1563-1568, 2010 | 39 | 2010 |
Batch versus flow lithiation–substitution of 1, 3, 4‐oxadiazoles: Exploitation of unstable intermediates using flow chemistry JYF Wong, JM Tobin, F Vilela, G Barker Chemistry–A European Journal 25 (53), 12439-12445, 2019 | 36 | 2019 |
Gold-catalyzed proto-and deuterodeboronation G Barker, S Webster, DG Johnson, R Curley, M Andrews, PC Young, ... The Journal of Organic Chemistry 80 (20), 9807-9816, 2015 | 34 | 2015 |
Chirality Transfer in Gold (I)‐Catalysed Direct Allylic Etherifications of Unactivated Alcohols: Experimental and Computational Study G Barker, DG Johnson, PC Young, SA Macgregor, AL Lee Chemistry–A European Journal 21 (39), 13748-13757, 2015 | 31 | 2015 |
Gold (I)‐Catalysed Direct Thioetherifications Using Allylic Alcohols: an Experimental and Computational Study L Herkert, SLJ Green, G Barker, DG Johnson, PC Young, SA Macgregor, ... Chemistry–A European Journal 20 (36), 11540-11548, 2014 | 29 | 2014 |
Gold (I)-catalysed one-pot synthesis of chromans using allylic alcohols and phenols E Coutant, PC Young, G Barker, AL Lee Beilstein Journal of Organic Chemistry 9 (1), 1797-1806, 2013 | 29 | 2013 |
Remarkable configurational stability of magnesiated nitriles. G Barker, MR Alshawish, MC Skilbeck, I Coldham Angewandte Chemie International Edition 52 (30), 2013 | 29 | 2013 |
Dehydrative thiolation of allenols: Indium vs gold catalysis S Webster, PC Young, G Barker, GM Rosair, AL Lee The Journal of Organic Chemistry 80 (3), 1703-1718, 2015 | 28 | 2015 |
The potential of a novel class of EPAC-selective agonists to combat cardiovascular inflammation G Barker, E Parnell, B Van Basten, H Buist, DR Adams, SJ Yarwood Journal of Cardiovascular Development and Disease 4 (4), 22, 2017 | 19 | 2017 |
Expanding the Tool Kit of Automated Flow Synthesis: Development of In-line Flash Chromatography Purification CG Thomson, C Banks, M Allen, G Barker, CR Coxon, AL Lee, F Vilela The Journal of Organic Chemistry 86 (20), 14079-14094, 2021 | 16 | 2021 |
Recent Developments in C− H Functionalisation of Benzofurans and Benzothiophenes D Morgan, SJ Yarwood, G Barker European Journal of Organic Chemistry 2021 (7), 1072-1102, 2021 | 14 | 2021 |
Synthesis and biochemical evaluation of noncyclic nucleotide exchange proteins directly activated by cAMP 1 (EPAC1) regulators P Wang, U Luchowska-Stanska, B Van Basten, H Chen, Z Liu, J Wiejak, ... Journal of medicinal chemistry 63 (10), 5159-5184, 2020 | 13 | 2020 |
Identification of a novel class of benzofuran oxoacetic acid-derived ligands that selectively activate cellular EPAC1 E M. Beck, E Parnell, A Cowley, A Porter, J Gillespie, J Robinson, ... Cells 8 (11), 1425, 2019 | 13 | 2019 |
O, Brien, P.; Campos, KR G Barker Org. Lett 12, 4176-4179, 2010 | 13 | 2010 |
Recent advances in benzylic and heterobenzylic lithiation JYF Wong, G Barker Tetrahedron 76 (50), 131704, 2020 | 11 | 2020 |
Flash chemistry enables high productivity metalation-substitution of 5-alkyltetrazoles JYF Wong, CG Thomson, F Vilela, G Barker Chemical Science 12 (40), 13413-13424, 2021 | 10 | 2021 |