| Activation of gene expression by small molecule transcription factors AK Mapp, AZ Ansari, M Ptashne, PB Dervan Proceedings of the National Academy of Sciences 97 (8), 3930-3935, 2000 | 312 | 2000 |
| Succinct synthesis of β-amino acids via chiral isoxazolines AA Fuller, B Chen, AR Minter, AK Mapp Journal of the American Chemical Society 127 (15), 5376-5383, 2005 | 178 | 2005 |
| Modular design of artificial transcription factors AZ Ansari, AK Mapp Current opinion in chemical biology 6 (6), 765-772, 2002 | 144 | 2002 |
| Towards a minimal motif for artificial transcriptional activators AZ Ansari, AK Mapp, DH Nguyen, PB Dervan, M Ptashne Chemistry & biology 8 (6), 583-592, 2001 | 143 | 2001 |
| A small molecule transcriptional activation domain AR Minter, BB Brennan, AK Mapp Journal of the American Chemical Society 126 (34), 10504-10505, 2004 | 129 | 2004 |
| A concise approach to structurally diverse β-amino acids AR Minter, AA Fuller, AK Mapp Journal of the American Chemical Society 125 (23), 6846-6847, 2003 | 126 | 2003 |
| Fine-tuning multiprotein complexes using small molecules AD Thompson, A Dugan, JE Gestwicki, AK Mapp ACS chemical biology 7 (8), 1311-1320, 2012 | 114 | 2012 |
| Direct Measurements of Oscillatory Glycolysis in Pancreatic Islet β-Cells Using Novel Fluorescence Resonance Energy Transfer (FRET) Biosensors for Pyruvate Kinase M2 Activity*♦ MJ Merrins, AR Van Dyke, AK Mapp, MA Rizzo, LS Satin Journal of Biological Chemistry 288 (46), 33312-33322, 2013 | 98 | 2013 |
| Total synthesis of myxalamide A AK Mapp, CH Heathcock The Journal of Organic Chemistry 64 (1), 23-27, 1999 | 92 | 1999 |
| Ordering a dynamic protein via a small-molecule stabilizer N Wang, CY Majmudar, WC Pomerantz, JK Gagnon, JD Sadowsky, ... Journal of the American Chemical Society 135 (9), 3363-3366, 2013 | 91 | 2013 |
| A TAD further: exogenous control of gene activation AK Mapp, AZ Ansari ACS Chemical Biology 2 (1), 62-75, 2007 | 90 | 2007 |
| Direct and propagated effects of small molecules on protein–protein interaction networks LC Cesa, AK Mapp, JE Gestwicki Frontiers in bioengineering and biotechnology 3, 119, 2015 | 70 | 2015 |
| Profiling the dynamic interfaces of fluorinated transcription complexes for ligand discovery and characterization WC Pomerantz, N Wang, AK Lipinski, R Wang, T Cierpicki, AK Mapp ACS chemical biology 7 (8), 1345-1350, 2012 | 70 | 2012 |
| Amphipathic small molecules mimic the binding mode and function of endogenous transcription factors SJ Buhrlage, CA Bates, SP Rowe, AR Minter, BB Brennan, CY Majmudar, ... ACS chemical biology 4 (5), 335-344, 2009 | 69 | 2009 |
| Prepaying the entropic cost for allosteric regulation in KIX SM Law, JK Gagnon, AK Mapp, CL Brooks III Proceedings of the National Academy of Sciences 111 (33), 12067-12072, 2014 | 67 | 2014 |
| Chemical approaches to transcriptional regulation CY Majmudar, AK Mapp Current opinion in chemical biology 9 (5), 467-474, 2005 | 67 | 2005 |
| Modulating the masters: chemical tools to dissect CBP and p300 function ME Breen, AK Mapp Current opinion in chemical biology 45, 195-203, 2018 | 66 | 2018 |
| Phosphorylation of Nanog is essential to regulate Bmi1 and promote tumorigenesis X Xie, L Piao, GS Cavey, M Old, TN Teknos, AK Mapp, Q Pan Oncogene 33 (16), 2040-2052, 2014 | 66 | 2014 |
| Synthesis of a 2,7-Dioxatricyclo[4.2.1.03,8]nonane: A Model Study for Possible Application in a Synthesis of Dictyoxetane KA Marshall, AK Mapp, CH Heathcock The Journal of Organic Chemistry 61 (26), 9135-9145, 1996 | 62 | 1996 |
| Sekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300 CY Majmudar, JW Højfeldt, CJ Arevang, WC Pomerantz, JK Gagnon, ... Angewandte Chemie 124 (45), 11420-11424, 2012 | 60 | 2012 |
Charles L. Brooks IIICyrus Levinthal Distinguished University Professor of Chemistry and Biophysics; Warner-Lambert/Parke在 umich.edu 的电子邮件经过验证
