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Jacob Janey
Jacob Janey
Research Fellow, Bristol-Myers Squibb
在 bms.com 的电子邮件经过验证
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Biocatalytic asymmetric synthesis of chiral amines from ketones applied to sitagliptin manufacture
CK Savile, JM Janey, EC Mundorff, JC Moore, S Tam, WR Jarvis, ...
Science 329 (5989), 305-309, 2010
19172010
Bayesian reaction optimization as a tool for chemical synthesis
BJ Shields, J Stevens, J Li, M Parasram, F Damani, JIM Alvarado, ...
Nature 590 (7844), 89-96, 2021
5812021
Recent advances in catalytic, enantioselective α aminations and α oxygenations of carbonyl compounds
JM Janey
Angewandte Chemie International Edition 44 (28), 4292-4300, 2005
3802005
The evolution of high-throughput experimentation in pharmaceutical development and perspectives on the future
SM Mennen, C Alhambra, CL Allen, M Barberis, S Berritt, TA Brandt, ...
Organic Process Research & Development 23 (6), 1213-1242, 2019
3612019
Chiral C2‐Symmetric CuII Complexes as Catalysts for Enantioselective Hetero‐Diels–Alder Reactions
DA Evans, EJ Olhava, JS Johnson, JM Janey
Angewandte Chemie International Edition 37 (24), 3372-3375, 1998
1791998
Chiral Salen-Aluminum Complexes as Catalysts for Enantioselective Aldol Reactions of Aldehydes and 5-Alkoxyoxazoles: An Efficient Approach to the Asymmetric Synthesis of syn …
DA Evans, JM Janey, N Magomedov, JS Tedrow
Angewandte Chemie (International Ed. in English) 40 (10), 1884-1888, 2001
1732001
1-Amino-3-siloxy-1, 3-butadienes: highly reactive dienes for the Diels− Alder reaction
SA Kozmin, JM Janey, VH Rawal
The Journal of Organic Chemistry 64 (9), 3039-3052, 1999
1461999
C2-Symmetric Cu(II) Complexes as Chiral Lewis Acids. Catalytic, Enantioselective Cycloadditions of Silyl Ketenes
DA Evans, JM Janey
Organic Letters 3 (13), 2125-2128, 2001
1202001
Development of a platform for near-infrared photoredox catalysis
BD Ravetz, NES Tay, CL Joe, M Sezen-Edmonds, MA Schmidt, Y Tan, ...
ACS central science 6 (11), 2053-2059, 2020
1102020
High-throughput automation in chemical process development
JA Selekman, J Qiu, K Tran, J Stevens, V Rosso, E Simmons, Y Xiao, ...
Annual review of chemical and biomolecular engineering 8 (1), 525-547, 2017
1082017
Proline-catalyzed, asymmetric Mannich reactions in the synthesis of a DPP-IV inhibitor
JM Janey, Y Hsiao, JD Armstrong
The Journal of Organic Chemistry 71 (1), 390-392, 2006
1062006
Racemic and Asymmetric Diels− Alder Reactions of 1-(2-Oxazolidinon-3-yl)-3-siloxy-1, 3-butadienes
JM Janey, T Iwama, SA Kozmin, VH Rawal
The Journal of Organic Chemistry 65 (26), 9059-9068, 2000
1052000
Fortschritte bei katalytischen enantioselektiven α‐Aminierungen und α‐Oxygenierungen von Carbonylverbindungen
JM Janey
Angewandte Chemie 117 (28), 4364-4372, 2005
842005
Synthesis of the HCV protease inhibitor vaniprevir (MK-7009) using ring-closing metathesis strategy
J Kong, C Chen, J Balsells-Padros, Y Cao, RF Dunn, SJ Dolman, J Janey, ...
The Journal of Organic Chemistry 77 (8), 3820-3828, 2012
812012
Adventures in atropisomerism: total synthesis of a complex active pharmaceutical ingredient with two chirality axes
G Beutner, R Carrasquillo, P Geng, Y Hsiao, EC Huang, J Janey, ...
Organic letters 20 (13), 3736-3740, 2018
542018
Chirale C2‐symmetrische CuII‐Komplexe als Katalysatoren für enantioselektive Hetero‐Diels‐Alder‐Reaktionen
DA Evans, EJ Olhava, JS Johnson, JM Janey
Angewandte Chemie 110 (24), 3553-3557, 1998
471998
Radical biocatalysis: Using non-natural single electron transfer mechanisms to access new enzymatic functions
TK Hyster
Synlett 31 (03), 248-254, 2020
462020
A practical synthesis of 5-lipoxygenase inhibitor MK-0633
F Gosselin, RA Britton, IW Davies, SJ Dolman, D Gauvreau, RS Hoerrner, ...
The Journal of Organic Chemistry 75 (12), 4154-4160, 2010
462010
Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
H Chen, SJ Collier, J Nazor, J Sukumaran, D Smith, JC Moore, G Hughes, ...
US Patent 9,487,760, 2016
382016
Direct Lewis Acid Catalyzed Conversion of Enantioenriched N-Acyloxazolidinones to Chiral Esters, Amides, and Acids
JM Stevens, AC Parra-Rivera, DD Dixon, GL Beutner, AJ DelMonte, ...
The Journal of Organic Chemistry 83 (23), 14245-14261, 2018
342018
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