A functionally characterized test set of human induced pluripotent stem cells GL Boulting, E Kiskinis, GF Croft, MW Amoroso, DH Oakley, BJ Wainger, ... Nature biotechnology 29 (3), 279-286, 2011 | 586 | 2011 |
Accelerated high-yield generation of limb-innervating motor neurons from human stem cells MW Amoroso, GF Croft, DJ Williams, S O'Keeffe, MA Carrasco, AR Davis, ... Journal of Neuroscience 33 (2), 574-586, 2013 | 301 | 2013 |
Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity EO Mazzoni, S Mahony, M Closser, CA Morrison, S Nedelec, DJ Williams, ... Nature neuroscience 16 (9), 1219-1227, 2013 | 241 | 2013 |
Differentiation of hypothalamic-like neurons from human pluripotent stem cells L Wang, K Meece, DJ Williams, KA Lo, M Zimmer, G Heinrich, JM Carli, ... The Journal of clinical investigation 125 (2), 796-808, 2015 | 138 | 2015 |
Rbfox splicing factors promote neuronal maturation and axon initial segment assembly M Jacko, SM Weyn-Vanhentenryck, JW Smerdon, R Yan, H Feng, ... Neuron 97 (4), 853-868. e6, 2018 | 110 | 2018 |
Inhibition of N-type calcium channels by activation of GPR35, an orphan receptor, heterologously expressed in rat sympathetic neurons J Guo, DJ Williams, HL Puhl, SR Ikeda Journal of Pharmacology and Experimental Therapeutics 324 (1), 342-351, 2008 | 101 | 2008 |
β-Cell replacement in mice using human type 1 diabetes nuclear transfer embryonic stem cells L Sui, N Danzl, SR Campbell, R Viola, D Williams, Y Xing, Y Wang, ... Diabetes 67 (1), 26-35, 2018 | 96 | 2018 |
A simple, highly efficient method for heterologous expression in mammalian primary neurons using cationic lipid-mediated mRNA transfection DJ Williams, HL Puhl III, SR Ikeda Frontiers in neuroscience 4, 181, 2010 | 81 | 2010 |
Reduced GABAergic neuron excitability, altered synaptic connectivity, and seizures in a KCNT1 gain-of-function mouse model of childhood epilepsy AN Shore, S Colombo, WF Tobin, S Petri, ER Cullen, S Dominguez, ... Cell reports 33 (4), 2020 | 53 | 2020 |
Quantification of human neuromuscular function through optogenetics OF Vila, SGM Uzel, SP Ma, D Williams, J Pak, RD Kamm, ... Theranostics 9 (5), 1232, 2019 | 50 | 2019 |
A stem cell-based screening platform identifies compounds that desensitize motor neurons to endoplasmic reticulum stress S Thams, ER Lowry, MH Larraufie, KJ Spiller, H Li, DJ Williams, P Hoang, ... Molecular Therapy 27 (1), 87-101, 2019 | 47 | 2019 |
Rapid modification of proteins using a rapamycin-inducible tobacco etch virus protease system DJ Williams, HL Puhl III, SR Ikeda PloS one 4 (10), e7474, 2009 | 42 | 2009 |
Parkin deficiency reduces hippocampal glutamatergic neurotransmission by impairing AMPA receptor endocytosis GP Cortese, M Zhu, D Williams, S Heath, CL Waites Journal of Neuroscience 36 (48), 12243-12258, 2016 | 40 | 2016 |
Bardet-Biedl syndrome proteins regulate intracellular signaling and neuronal function in patient-specific iPSC-derived neurons L Wang, Y Liu, G Stratigopoulos, S Panigrahi, L Sui, Y Zhang, CA Leduc, ... The Journal of clinical investigation 131 (8), 2021 | 38 | 2021 |
Altered function and maturation of primary cortical neurons from a 22q11. 2 deletion mouse model of schizophrenia Z Sun, DJ Williams, B Xu, JA Gogos Translational psychiatry 8 (1), 85, 2018 | 37 | 2018 |
Modulation of neurite outgrowth by activation of calcium‐permeable kainate receptors expressed by rat nociceptive‐like dorsal root ganglion neurons DJ Joseph, DJ Williams, AB MacDermott Developmental neurobiology 71 (10), 818-835, 2011 | 34 | 2011 |
The sources and sequestration of Ca2+ contributing to neuroeffector Ca2+ transients in the mouse vas deferens KL Brain, AM Cuprian, DJ Williams, TC Cunnane The Journal of physiology 553 (2), 627-635, 2003 | 31 | 2003 |
N-Arachidonoyl l-Serine, a Putative Endocannabinoid, Alters the Activation of N-Type Ca2+ Channels in Sympathetic Neurons J Guo, DJ Williams, SR Ikeda Journal of neurophysiology 100 (2), 1147-1151, 2008 | 25 | 2008 |
Intranuclear microinjection of DNA into dissociated adult mammalian neurons VB Lu, DJ Williams, YJ Won, SR Ikeda JoVE (Journal of Visualized Experiments), e1614, 2009 | 23 | 2009 |
Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency BJ González, H Zhao, J Niu, DJ Williams, J Lee, CN Goulbourne, Y Xing, ... Communications Biology 5 (1), 779, 2022 | 16 | 2022 |