Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl-and butyryl-cholinesterase F Nachon, E Carletti, C Ronco, M Trovaslet, Y Nicolet, L Jean, PY Renard Biochemical Journal 453 (3), 393-399, 2013 | 403 | 2013 |
Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents G Mercey, T Verdelet, J Renou, M Kliachyna, R Baati, F Nachon, L Jean, ... Accounts of chemical research 45 (5), 756-766, 2012 | 396 | 2012 |
Water-soluble BODIPY derivatives SL Niu, G Ulrich, R Ziessel, A Kiss, PY Renard, A Romieu Organic letters 11 (10), 2049-2052, 2009 | 236 | 2009 |
High‐throughput screening of enantioselective catalysts by immunoassay F Taran, C Gauchet, B Mohar, S Meunier, A Valleix, PY Renard, ... Angewandte Chemie International Edition 41 (1), 124-127, 2002 | 179 | 2002 |
Covalent modification of biomolecules through maleimide-based labeling strategies K Renault, JW Fredy, PY Renard, C Sabot Bioconjugate Chemistry 29 (8), 2497-2513, 2018 | 175 | 2018 |
Design and synthesis of chemiluminescent probes for the detection of cholinesterase activity S Sabelle, PY Renard, K Pecorella, S de Suzzoni-Dézard, C Créminon, ... Journal of the American Chemical Society 124 (17), 4874-4880, 2002 | 161 | 2002 |
7-hydroxycoumarin-hemicyanine hybrids: a new class of far-red emitting fluorogenic dyes. JA Richard, M Massonneau, PY Renard, A Romieu Organic letters 10 (19), 4175-4178, 2008 | 132 | 2008 |
First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase G Mercey, T Verdelet, G Saint-André, E Gillon, A Wagner, R Baati, L Jean, ... Chemical communications 47 (18), 5295-5297, 2011 | 128 | 2011 |
Thyroid hormone improves postischaemic recovery of function while limiting apoptosis: a new therapeutic approach to support hemodynamics in the setting of ischaemia-reperfusion? C Pantos, I Mourouzis, T Saranteas, G Clavé, H Ligeret, ... Basic Research in Cardiology 104, 69-77, 2009 | 125 | 2009 |
Novel water-soluble near-infrared cyanine dyes: synthesis, spectral properties, and use in the preparation of internally quenched fluorescent probes C Bouteiller, G Clavé, A Bernardin, B Chipon, M Massonneau, PY Renard, ... Bioconjugate chemistry 18 (4), 1303-1317, 2007 | 125 | 2007 |
Human butyrylcholinesterase produced in insect cells: huprine‐based affinity purification and crystal structure X Brazzolotto, M Wandhammer, C Ronco, M Trovaslet, L Jean, ... The FEBS journal 279 (16), 2905-2916, 2012 | 112 | 2012 |
Water‐Soluble Red‐Emitting Distyryl‐Borondipyrromethene (BODIPY) Dyes for Biolabeling S Niu, C Massif, G Ulrich, PY Renard, A Romieu, R Ziessel Chemistry–A European Journal 18 (23), 7229-7242, 2012 | 105 | 2012 |
Azo‐Based Fluorogenic Probes for Biosensing and Bioimaging: Recent Advances and Upcoming Challenges A Chevalier, PY Renard, A Romieu Chemistry–An Asian Journal 12 (16), 2008-2028, 2017 | 103 | 2017 |
Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine-aldoxime and-amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited … M Kliachyna, G Santoni, V Nussbaum, J Renou, B Sanson, JP Colletier, ... European Journal of Medicinal Chemistry 78, 455-467, 2014 | 99 | 2014 |
Water-solubilisation and bio-conjugation of a red-emitting BODIPY marker SL Niu, C Massif, G Ulrich, R Ziessel, PY Renard, A Romieu Organic & biomolecular chemistry 9 (1), 66-69, 2011 | 94 | 2011 |
Easy access to phosphonothioates PY Renard, H Schwebel, P Vayron, L Josien, A Valleix, C Mioskowski Chemistry–A European Journal 8 (13), 2910-2916, 2002 | 91 | 2002 |
Lewis acid catalyzed room-temperature Michaelis–Arbuzov rearrangement PY Renard, P Vayron, E Leclerc, A Valleix, C Mioskowski Angewandte Chemie-International Edition 42 (21), 2389-2392, 2003 | 85 | 2003 |
Development of a new nonpeptidic self-immolative spacer. Application to the design of protease sensing fluorogenic probes Y Meyer, JA Richard, M Massonneau, PY Renard, A Romieu Organic letters 10 (8), 1517-1520, 2008 | 84 | 2008 |
Chemiluminescent probe for the in vitro detection of protease activity JA Richard, L Jean, A Romieu, M Massonneau, P Noack-Fraissignes, ... Organic letters 9 (23), 4853-4855, 2007 | 79 | 2007 |
Design, synthesis and evaluation of new α-nucleophiles for the hydrolysis of organophosphorus nerve agents: application to the reactivation of phosphorylated acetylcholinesterase G Saint-André, M Kliachyna, S Kodepelly, L Louise-Leriche, E Gillon, ... Tetrahedron 67 (34), 6352-6361, 2011 | 78 | 2011 |