A photocaged, water-oxidizing, and nucleolus-targeted Pt (IV) complex with a distinct anticancer mechanism Z Deng, N Wang, Y Liu, Z Xu, Z Wang, TC Lau, G Zhu Journal of the American Chemical Society 142 (17), 7803-7812, 2020 | 147 | 2020 |
Phorbiplatin, a highly potent Pt (IV) antitumor prodrug that can be controllably activated by red light Z Wang, N Wang, SC Cheng, K Xu, Z Deng, S Chen, Z Xu, K Xie, MK Tse, ... Chem 5 (12), 3151-3165, 2019 | 115 | 2019 |
A platinum (IV) anticancer prodrug targeting nucleotide excision repair to overcome cisplatin resistance Z Wang, Z Xu, G Zhu Angewandte Chemie International Edition 55 (50), 15564-15568, 2016 | 114 | 2016 |
A cisplatin‐loaded immunochemotherapeutic nanohybrid bearing immune checkpoint inhibitors for enhanced cervical cancer therapy N Wang, Z Wang, Z Xu, X Chen, G Zhu Angewandte Chemie International Edition 57 (13), 3426-3430, 2018 | 109 | 2018 |
Recent advances in the synthesis, stability, and activation of platinum (IV) anticancer prodrugs Z Xu, Z Wang, Z Deng, G Zhu Coordination Chemistry Reviews 442, 213991, 2021 | 101 | 2021 |
An upconversion nanoplatform for simultaneous photodynamic therapy and Pt chemotherapy to combat cisplatin resistance F Ai, T Sun, Z Xu, Z Wang, W Kong, MW To, F Wang, G Zhu Dalton Transactions 45 (33), 13052-13060, 2016 | 66 | 2016 |
A cancer cell-selective and low-toxic bifunctional heterodinuclear Pt (IV)–Ru (II) anticancer prodrug L Ma, X Lin, C Li, Z Xu, CY Chan, MK Tse, P Shi, G Zhu Inorganic Chemistry 57 (5), 2917-2924, 2018 | 61 | 2018 |
Monochalcoplatin: An Actively Transported, Quickly Reducible, and Highly Potent PtIV Anticancer Prodrug L Ma, N Wang, R Ma, C Li, Z Xu, MK Tse, G Zhu Angewandte Chemie International Edition 57 (29), 9098-9102, 2018 | 58 | 2018 |
An intramolecular photoswitch can significantly promote photoactivation of Pt (IV) prodrugs Z Deng, C Li, S Chen, Q Zhou, Z Xu, Z Wang, H Yao, H Hirao, G Zhu Chemical Science 12 (19), 6536-6542, 2021 | 36 | 2021 |
Synthesis, structure, and cytotoxicity of oxaliplatin-based platinum (IV) anticancer prodrugs bearing one axial fluoride Z Xu, HM Chan, C Li, Z Wang, MK Tse, Z Tong, G Zhu Inorganic Chemistry 57 (14), 8227-8235, 2018 | 26 | 2018 |
Mono-and di-bromo platinum (IV) prodrugs via oxidative bromination: synthesis, characterization, and cytotoxicity Z Xu, Z Wang, SM Yiu, G Zhu Dalton Transactions 44 (46), 19918-19926, 2015 | 26 | 2015 |
Synthesis and cytotoxic study of a platinum (IV) anticancer prodrug with selectivity toward luteinizing hormone-releasing hormone (LHRH) receptor-positive cancer cells H Yao, Z Xu, C Li, MK Tse, Z Tong, G Zhu Inorganic Chemistry 58 (16), 11076-11084, 2019 | 22 | 2019 |
Multitargeted platinum (IV) anticancer complexes bearing pyridinyl ligands as axial leaving groups Q Zhou, S Chen, Z Xu, G Liu, S Zhang, Z Wang, MK Tse, SM Yiu, G Zhu Angewandte Chemie International Edition 62 (18), e202302156, 2023 | 16 | 2023 |
Synthesis, cytotoxicity, and mechanistic investigation of platinum (IV) Anticancer Complexes Conjugated with Poly (ADP-ribose) polymerase inhibitors Z Xu, C Li, Q Zhou, Z Deng, Z Tong, MK Tse, G Zhu Inorganic Chemistry 58 (23), 16279-16291, 2019 | 16 | 2019 |
On the hydrolytic stability of unsymmetric platinum (iv) anticancer prodrugs containing axial halogens Z Xu, WK Tang, Q Zhou, S Chen, CK Siu, G Zhu Inorganic Chemistry Frontiers 8 (16), 3794-3802, 2021 | 15 | 2021 |
Halogenated PtIV Complexes from N‐Halosuccinimide Oxidation of PtII Antitumor Drugs: Synthesis, Mechanistic Investigation, and Cytotoxicity Z Xu, C Li, Z Tong, L Ma, MK Tse, G Zhu European Journal of Inorganic Chemistry 2017 (12), 1706-1712, 2017 | 14 | 2017 |
Design of Tetrazolium Cations for the Release of Antiproliferative Formazan Chelators in Mammalian Cells Z Xu, YS Sung, E Tomat Journal of the American Chemical Society 145 (28), 15197-15206, 2023 | 4 | 2023 |
Advances in technical strategies for monitoring the reduction of platinum (IV) complexes S Chen, Q Zhou, KY Ng, Z Xu, W Xu, G Zhu Inorganic Chemistry Frontiers, 2024 | | 2024 |
Ligand substitution reactions afford oxaliplatin-based platinum (IV) complexes bearing axial alkoxido ligands Z Xu, L Lin, B Fu, FP Huang, Q Zhou, G Zhu, Z Wang Inorganic Chemistry Frontiers 10 (20), 6058-6066, 2023 | | 2023 |
Platinum complex, its preparation and therapeutic use G Zhu, Z Xu, Z Qiyuan US Patent App. 17/327,517, 2021 | | 2021 |