Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson’s disease TR Sampson, JW Debelius, T Thron, S Janssen, GG Shastri, ZE Ilhan, ... Cell 167 (6), 1469-1480. e12, 2016 | 3207 | 2016 |
The central nervous system and the gut microbiome G Sharon, TR Sampson, DH Geschwind, SK Mazmanian Cell 167 (4), 915-932, 2016 | 1299 | 2016 |
Control of brain development, function, and behavior by the microbiome TR Sampson, SK Mazmanian Cell host & microbe 17 (5), 565-576, 2015 | 1169 | 2015 |
A CRISPR/Cas system mediates bacterial innate immune evasion and virulence TR Sampson, SD Saroj, AC Llewellyn, YL Tzeng, DS Weiss Nature 497 (7448), 254-257, 2013 | 547 | 2013 |
A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice TR Sampson, C Challis, N Jain, A Moiseyenko, MS Ladinsky, GG Shastri, ... elife 9, e53111, 2020 | 343 | 2020 |
Gut-seeded α-synuclein fibrils promote gut dysfunction and brain pathology specifically in aged mice C Challis, A Hori, TR Sampson, BB Yoo, RC Challis, AM Hamilton, ... Nature Neuroscience 23 (3), 327-336, 2020 | 313 | 2020 |
Cas9-mediated targeting of viral RNA in eukaryotic cells AA Price, TR Sampson, HK Ratner, A Grakoui, DS Weiss Proceedings of the National Academy of Sciences 112 (19), 6164-6169, 2015 | 296 | 2015 |
Rapid killing of Acinetobacter baumannii by polymyxins is mediated by a hydroxyl radical death pathway TR Sampson, X Liu, MR Schroeder, CS Kraft, EM Burd, DS Weiss Antimicrobial agents and chemotherapy 56 (11), 5642-5649, 2012 | 237 | 2012 |
Gut microbiota regulate Alzheimer’s disease pathologies and cognitive disorders via PUFA-associated neuroinflammation C Chen, J Liao, Y Xia, X Liu, R Jones, J Haran, B McCormick, ... Gut 71 (11), 2233-2252, 2022 | 184 | 2022 |
Subversion of host recognition and defense systems by Francisella spp CL Jones, BA Napier, TR Sampson, AC Llewellyn, MR Schroeder, ... Microbiology and Molecular Biology Reviews 76 (2), 383-404, 2012 | 167 | 2012 |
Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms ZD Wallen, A Demirkan, G Twa, G Cohen, MN Dean, DG Standaert, ... Nature communications 13 (1), 6958, 2022 | 122 | 2022 |
A CRISPR-Cas system enhances envelope integrity mediating antibiotic resistance and inflammasome evasion TR Sampson, BA Napier, MR Schroeder, R Louwen, J Zhao, CY Chin, ... Proceedings of the National Academy of Sciences 111 (30), 11163-11168, 2014 | 108 | 2014 |
CRISPR-Cas systems: new players in gene regulation and bacterial physiology TR Sampson, DS Weiss Frontiers in cellular and infection microbiology 4, 37, 2014 | 96 | 2014 |
Exploiting CRISPR/C as systems for biotechnology TR Sampson, DS Weiss Bioessays 36 (1), 34-38, 2014 | 96 | 2014 |
Cas9-nucleic acid complexes and uses related thereto DS Weiss, A Grakoui, TR Sampson, AA Price US Patent 10,544,405, 2020 | 90 | 2020 |
Mycobacteriophages BPs, Angel and Halo: comparative genomics reveals a novel class of ultra-small mobile genetic elements T Sampson, GW Broussard, LJ Marinelli, D Jacobs-Sera, M Ray, CC Ko, ... Microbiology 155 (9), 2962-2977, 2009 | 76 | 2009 |
I can see CRISPR now, even when phage are gone: a view on alternative CRISPR-Cas functions from the prokaryotic envelope HK Ratner, TR Sampson, DS Weiss Current opinion in infectious diseases 28 (3), 267-274, 2015 | 57 | 2015 |
Alternative roles for CRISPR/Cas systems in bacterial pathogenesis TR Sampson, DS Weiss PLoS pathogens 9 (10), e1003621, 2013 | 55 | 2013 |
Repression of bacterial lipoprotein production by Francisella novicida facilitates evasion of innate immune recognition CL Jones, TR Sampson, HI Nakaya, B Pulendran, DS Weiss Cellular microbiology 14 (10), 1531-1543, 2012 | 47 | 2012 |
The impact of indigenous microbes on Parkinson's disease T Sampson Neurobiology of disease 135, 104426, 2020 | 38 | 2020 |