Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease RN Helsley, V Varadharajan, AL Brown, AD Gromovsky, RC Schugar, ... Elife 8, e49882, 2019 | 125 | 2019 |
Oleosin is bifunctional enzyme that has both monoacylglycerol acyltransferase and phospholipase activities V Parthibane, S Rajakumari, V Venkateshwari, R Iyappan, ... Journal of Biological Chemistry 287 (3), 1946-1954, 2012 | 115 | 2012 |
Serine/threonine/tyrosine protein kinase phosphorylates oleosin, a regulator of lipid metabolic functions V Parthibane, R Iyappan, A Vijayakumar, V Venkateshwari, ... Plant physiology 159 (1), 95-104, 2012 | 57 | 2012 |
Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice RN Helsley, T Miyata, A Kadam, V Varadharajan, N Sangwan, EC Huang, ... Elife 11, e76554, 2022 | 32 | 2022 |
Strain dropouts reveal interactions that govern the metabolic output of the gut microbiome M Wang, LJ Osborn, S Jain, X Meng, A Weakley, J Yan, WJ Massey, ... Cell 186 (13), 2839-2852. e21, 2023 | 26 | 2023 |
MBOAT7-driven phosphatidylinositol remodeling promotes the progression of clear cell renal carcinoma CKA Neumann, DJ Silver, V Venkateshwari, R Zhang, CA Traughber, ... Molecular metabolism 34, 136-145, 2020 | 23 | 2020 |
Membrane-bound O-acyltransferase 7 (MBOAT7)-driven phosphatidylinositol remodeling in advanced liver disease V Varadharajan, WJ Massey, JM Brown Journal of Lipid Research 63 (7), 2022 | 21 | 2022 |
A gut microbial metabolite of dietary polyphenols reverses obesity-driven hepatic steatosis LJ Osborn, K Schultz, W Massey, B DeLucia, I Choucair, V Varadharajan, ... Proceedings of the National Academy of Sciences 119 (48), e2202934119, 2022 | 18 | 2022 |
Leaf lipidome and transcriptome profiling of Portulaca oleracea: characterization of lysophosphatidylcholine acyltransferase V Venkateshwari, A Vijayakumar, AK Vijayakumar, LPA Reddy, ... Planta 248, 347-367, 2018 | 12 | 2018 |
MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis VV Phadnis, J Snider, V Varadharajan, I Ramachandiran, AA Deik, ... Cell reports 42 (9), 2023 | 11 | 2023 |
MBOAT7-driven lysophosphatidylinositol acylation in adipocytes contributes to systemic glucose homeostasis WJ Massey, V Varadharajan, R Banerjee, AL Brown, AJ Horak, RC Hohe, ... Journal of Lipid Research 64 (4), 2023 | 10 | 2023 |
Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism L Zhao, Z Qiu, Z Yang, L Xu, TM Pearce, Q Wu, K Yang, FL Li, O Saulnier, ... Nature Cancer 5 (1), 147-166, 2024 | 6 | 2024 |
Hepatocyte activity of the cholesterol sensor smoothened regulates cholesterol and bile acid homeostasis in mice GD Dalton, SH Oh, L Tang, S Zhang, AL Brown, V Varadharajan, ... Iscience 24 (9), 2021 | 4 | 2021 |
Membrane-bound O-acyltransferase 7 (MBOAT7) shapes lysosomal lipid homeostasis and function to control alcohol-associated liver injury V Varadharajan, I Ramachandiran, WJ Massey, R Jain, R Banerjee, ... Elife 12, RP92243, 2024 | 3 | 2024 |
Loss of carnitine palmitoyltransferase 1a reduces docosahexaenoic acid-containing phospholipids and drives sexually dimorphic liver disease in mice MM Zelows, C Cady, N Dharanipragada, AE Mead, ZA Kipp, EA Bates, ... Molecular Metabolism 78, 101815, 2023 | 1 | 2023 |
Circulating Gut Microbe-Derived Metabolites Are Associated with Hepatocellular Carcinoma FAJMB Rakhee Banerjee,Chase J. Wehrle,Zeneng Wang,Jennifer D. Wilcox,Vinayak ... Biomedicines 12 (9), 14, 2024 | | 2024 |
The nonvesicular sterol transporter Aster-C plays a minor role in whole body cholesterol balance R Banerjee, RC Hohe, S Cao, BM Jung, AJ Horak, I Ramachandiran, ... Frontiers in Physiology 15, 1371096, 2024 | | 2024 |
FEATURED RESEARCH CH Brown | | 2014 |