Highly reactive oxygen species: detection, formation, and possible functions W Freinbichler, MA Colivicchi, C Stefanini, L Bianchi, C Ballini, B Misini, ... Cellular and molecular life sciences 68, 2067-2079, 2011 | 219 | 2011 |
Intrinsic subtype switching and acquired ERBB2/HER2 amplifications and mutations in breast cancer brain metastases N Priedigkeit, RJ Hartmaier, Y Chen, D Vareslija, A Basudan, RJ Watters, ... JAMA oncology 3 (5), 666-671, 2017 | 164 | 2017 |
Transcriptome characterization of matched primary breast and brain metastatic tumors to detect novel actionable targets D Varešlija, N Priedigkeit, A Fagan, S Purcell, N Cosgrove, PJ O’Halloran, ... JNCI: Journal of the National Cancer Institute 111 (4), 388-398, 2019 | 98 | 2019 |
Brain metastasis cell lines panel: a public resource of organotropic cell lines M Valiente, AED Van Swearingen, CK Anders, A Bairoch, A Boire, PD Bos, ... Cancer research 80 (20), 4314-4323, 2020 | 65 | 2020 |
AIB1: ERα Transcriptional Activity Is Selectively Enhanced in Aromatase Inhibitor–Resistant Breast Cancer Cells J O'Hara, D Vareslija, J McBryan, F Bane, P Tibbitts, C Byrne, RM Conroy, ... Clinical Cancer Research 18 (12), 3305-3315, 2012 | 54 | 2012 |
Mapping molecular subtype specific alterations in breast cancer brain metastases identifies clinically relevant vulnerabilities N Cosgrove, D Varešlija, S Keelan, A Elangovan, JM Atkinson, ... Nature communications 13 (1), 514, 2022 | 52 | 2022 |
Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism C Monteiro, L Miarka, M Perea-García, N Priego, P Garcia-Gomez, ... Nature Medicine 28 (4), 752-765, 2022 | 41 | 2022 |
6-Hydroxydopamine: A far from simple neurotoxin D Varešlija, KF Tipton, GP Davey, AG McDonald Journal of Neural Transmission 127, 213-230, 2020 | 40 | 2020 |
Network analysis of SRC-1 reveals a novel transcription factor hub which regulates endocrine resistant breast cancer. YLS Browne AL, Charmsaz S, Varešlija D, Fagan A, Cosgrove N, Cocchiglia S ... Oncogene, 2018 | 33 | 2018 |
Adaptation to AI therapy in breast cancer can induce dynamic alterations in ER activity resulting in estrogen-independent metastatic tumors D Varešlija, J McBryan, A Fagan, AM Redmond, Y Hao, AH Sims, ... Clinical Cancer Research 22 (11), 2765-2777, 2016 | 33 | 2016 |
Transcriptomic profiling of sequential tumors from breast cancer patients provides a global view of metastatic expression changes following endocrine therapy J McBryan, A Fagan, D McCartan, FT Bane, D Varešlija, S Cocchiglia, ... Clinical Cancer Research 21 (23), 5371-5379, 2015 | 33 | 2015 |
A novel panel of differentially-expressed microRNAs in breast cancer brain metastasis may predict patient survival A Giannoudis, K Clarke, R Zakaria, D Varešlija, M Farahani, L Rainbow, ... Scientific Reports 9 (1), 18518, 2019 | 26 | 2019 |
FiTAc-seq: fixed-tissue ChIP-seq for H3K27ac profiling and super-enhancer analysis of FFPE tissues A Font-Tello, N Kesten, Y Xie, L Taing, D Varešlija, LS Young, AA Hamid, ... Nature Protocols, 1-16, 2020 | 22 | 2020 |
Epigenome-wide SRC-1–mediated gene silencing represses cellular differentiation in advanced breast Cancer E Ward, D Varešlija, S Charmsaz, A Fagan, AL Browne, N Cosgrove, ... Clinical Cancer Research 24 (15), 3692-3703, 2018 | 19 | 2018 |
BET inhibition as a rational therapeutic strategy for invasive lobular breast cancer L Walsh, KE Haley, B Moran, B Mooney, F Tarrant, SF Madden, ... Clinical Cancer Research 25 (23), 7139-7150, 2019 | 17 | 2019 |
Patient-derived xenografts of breast cancer D Varešlija, S Cocchiglia, C Byrne, L Young Mammary Gland Development: Methods and Protocols, 327-336, 2017 | 17 | 2017 |
A clinically compatible drug‐screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis L Zhu, D Retana, P García‐Gómez, L Álvaro‐Espinosa, N Priego, ... EMBO Molecular Medicine 14 (3), e14552, 2022 | 13 | 2022 |
Low cleaved caspase-7 levels indicate unfavourable outcome across all breast cancers AU Lindner, F Lucantoni, D Varešlija, A Resler, BM Murphy, ... Journal of Molecular Medicine 96, 1025-1037, 2018 | 13 | 2018 |
Comparative analysis of the AIB1 interactome in breast cancer reveals MTA2 as a repressive partner which silences E-Cadherin to promote EMT and associates with a pro-metastatic … D Varešlija, E Ward, SP Purcell, NS Cosgrove, S Cocchiglia, ... Oncogene 40 (7), 1318-1331, 2021 | 11 | 2021 |
Altered steroid milieu in AI-resistant breast cancer facilitates AR mediated gene-expression associated with poor response to therapy L Creevey, R Bleach, SF Madden, S Toomey, FT Bane, D Varešlija, ... Molecular Cancer Therapeutics 18 (10), 1731-1743, 2019 | 9 | 2019 |