Molecular insights into the causes of human thymic hypoplasia with animal models P Bhalla, CA Wysocki, NSC van Oers Frontiers in immunology 11, 830, 2020 | 23 | 2020 |
Thymus functionality needs more than a few TECs P Bhalla, DM Su, NSC van Oers Frontiers in immunology 13, 864777, 2022 | 20 | 2022 |
Yeast PAF1 complex counters the pol III accumulation and replication stress on the tRNA genes P Bhalla, A Shukla, DV Vernekar, AG Arimbasseri, KS Sandhu, ... Scientific reports 9 (1), 12892, 2019 | 14 | 2019 |
Interactome of the yeast RNA polymerase III transcription machinery constitutes several chromatin modifiers and regulators of the genes transcribed by RNA polymerase II P Bhalla, DV Vernekar, B Gilquin, Y Couté, P Bhargava Gene 702, 205-214, 2019 | 10 | 2019 |
Transcription-dependent enrichment of the yeast FACT complex influences nucleosome dynamics on the RNA polymerase III-transcribed genes A Shukla, P Bhalla, PK Potdar, P Jampala, P Bhargava RNA 27 (3), 273-290, 2021 | 9 | 2021 |
Mesenchymal cell replacement corrects thymic hypoplasia in murine models of 22q11. 2 deletion syndrome P Bhalla, Q Du, A Kumar, C Xing, A Moses, I Dozmorov, CA Wysocki, ... The Journal of clinical investigation 132 (22), 2023 | 3 | 2023 |
Comprehensive phenotypic analysis of diverse FOXN1 variants A Moses, P Bhalla, A Thompson, L Lai, FS Coskun, CM Seroogy, ... Journal of Allergy and Clinical Immunology 152 (5), 1273-1291. e15, 2023 | 2 | 2023 |
Yeast PAF1 complex restricts the accumulation of RNA polymerase III and counters the replication stress on the transcribed genes P Bhalla, D Vernekar, A Shukla, B Gilquin, Y Couté, P Bhargava bioRxiv, 339499, 2018 | 1 | 2018 |
152 Thymus Hypoplasia in 22q11. 2DS (DiGeorge): From Mechanism to Restoration P Bhalla, N Ahuja, A Kumar, A Moses, C Xing, O Cleaver, C Wysocki, ... Clinical Immunology 262, 110094, 2024 | | 2024 |
A human ITPR3 variant causes a dominant negative attenuation of calcium responses with immunodeficiency and growth delay confirmed in a mouse model C Wysocki, A Moses, H Zhang, A Satterthwaite, K Ottens, C Xing, P Bhalla, ... Clinical Immunology 250, 109379, 2023 | | 2023 |
Thymus Tissue Regeneration in 22q11. 2DS Mouse Models (DiGeorge) using Mesenchymal Cell Replacement or Vasodilators P Bhalla, A Moses, N van Oers, A Kumar, C Xing, O Cleaver, ... Clinical Immunology 250, 109429, 2023 | | 2023 |
Defining the impact of FOXN1 variants with functional assays and reaggregate thymus organ cultures reveals those with loss-and gain-of function and dominant negative consequences A Moses, P Bhalla, C Wysocki, C Seroogy, MT de la Morena, N van Oers Clinical Immunology 250, 109368, 2023 | | 2023 |
Characterization of Human FOXN1 Mutations Uncovers both Loss-and Gain-of-Function Outcomes NS van Oers, A Moses, P Bhalla, C Wysocki, C Seroogy, ML Markert, ... The Journal of Immunology 208 (1_Supplement), 159.10-159.10, 2022 | | 2022 |
22q11. 2 Deletion Syndrome Causes a Thymus Hypoplasia Corrected by Mesenchymal Cell Replacement NS van Oers, P Bhalla, A Moses, A Kumar, C Xing, C Wysocki, O Cleaver, ... The Journal of Immunology 208 (1_Supplement), 159.07-159.07, 2022 | | 2022 |
Characterization of Diverse Human FOXN1 Mutations Reveals Complete and Partial Loss-of-Function and Gain-of-Function Consequences N van Oers, A Moses, P Bhalla, C Wysocki, C Seroogy, ML Markert, ... JOURNAL OF CLINICAL IMMUNOLOGY 42 (SUPPL 1), S14-S15, 2022 | | 2022 |
Thymus Hypoplasia Resulting from 22q11. 2 Deletion Syndrome Corrected by Reconstitution with Normal Mesenchymal Cells P Bhalla, I Dozmorov, C Wysocki, A Kumar, C Xing, O Cleaver, ... JOURNAL OF CLINICAL IMMUNOLOGY 41 (SUPPL 1), S14-S15, 2021 | | 2021 |
Normal Mesenchymal Cells Can Restore Thymic Tissue Expansion In The Setting of 22q11. 2 Deletion Syndrome N van Oers, B Pratibha, A Thompson, C Wysocki, I Dozmorov, ... JOURNAL OF CLINICAL IMMUNOLOGY 40 (SUPPL 1), S75-S76, 2020 | | 2020 |
Yeast PAF1 complex counters the pol III accumulation and replication stress on the tRNA genes GA Arimbasseri, KS Sandhu, P Bhargava, P Bhalla, A Shukla, ... Springer Nature Limited, 2019 | | 2019 |