Azide and cyanide displacements via hypervalent silicate intermediates ED Soli, AS Manoso, MC Patterson, P DeShong, DA Favor, R Hirschmann, ... The Journal of Organic Chemistry 64 (9), 3171-3177, 1999 | 207 | 1999 |
Total synthesis of (+)-azaspiracid-1. An exhibition of the intricacies of complex molecule synthesis DA Evans, L Kværnø, TB Dunn, A Beauchemin, B Raymer, JA Mulder, ... Journal of the American Chemical Society 130 (48), 16295-16309, 2008 | 120 | 2008 |
Total Synthesis of (+)‐Azaspiracid‐1. Part II: Synthesis of the EFGHI Sulfone and Completion of the Synthesis DA Evans, TB Dunn, L Kværnø, A Beauchemin, B Raymer, EJ Olhava, ... Angewandte Chemie 119 (25), 4782-4787, 2007 | 69 | 2007 |
Chemically diverse group I p21-activated kinase (PAK) inhibitors impart acute cardiovascular toxicity with a narrow therapeutic window J Rudolph, LJ Murray, CO Ndubaku, T O’Brien, E Blackwood, W Wang, ... Journal of medicinal chemistry 59 (11), 5520-5541, 2016 | 67 | 2016 |
[1, 8] naphthyridin-2-ones and related compounds for the treatment of schizophrenia DS Johnson, JT Repine, AD White US Patent 7,160,888, 2007 | 64 | 2007 |
Molecular modeling, synthesis, and structures of N-methylated 3, 5-linked pyrrolin-4-ones toward the creation of a privileged nonpeptide scaffold AB Smith III, DA Favor, PA Sprengeler, MC Guzman, PJ Carroll, GT Furst, ... Bioorganic & medicinal chemistry 7 (1), 9-22, 1999 | 55 | 1999 |
A second-generation synthesis of scalemic 3, 5, 5-trisubstituted pyrrolin-4-ones: Incorporation of functionalized amino acid side-chains AB Smith III, AB Benowitz, DA Favor, PA Sprengeler, R Hirschmann Tetrahedron letters 38 (22), 3809-3812, 1997 | 39 | 1997 |
Discovery of PF-00217830: Aryl piperazine napthyridinones as D2 partial agonists for schizophrenia and bipolar disorder DS Johnson, C Choi, LK Fay, DA Favor, JT Repine, AD White, HC Akunne, ... Bioorganic & medicinal chemistry letters 21 (9), 2621-2625, 2011 | 38 | 2011 |
Synthesis of polypyrrolinones on solid support AB Smith, H Liu, H Okumura, DA Favor, R Hirschmann Organic Letters 2 (14), 2041-2044, 2000 | 32 | 2000 |
Pyrrolo [2, 1-f][1, 2, 4] triazines: from C-nucleosides to kinases and back again, the remarkable journey of a versatile nitrogen heterocycle GR Ott, DA Favor Bioorganic & Medicinal Chemistry Letters 27 (18), 4238-4246, 2017 | 30 | 2017 |
Synthesis of monofluorinated 1-(naphthalen-1-yl) piperazines JT Repine, DS Johnson, AD White, DA Favor, MA Stier, J Yip, T Rankin, ... Tetrahedron letters 48 (31), 5539-5541, 2007 | 28 | 2007 |
Synthesis of methyl-, fluoro-, and chloro-substituted 6-hydroxyisoindolin-1-ones JJ Powers, DA Favor, T Rankin, R Sharma, C Pandit, A Jeganathan, ... Tetrahedron Letters 50 (12), 1267-1269, 2009 | 22 | 2009 |
6-Alkoxyisoindolin-1-one based dopamine D2 partial agonists as potential antipsychotics DA Favor, JJ Powers, AD White, LW Fitzgerald, V Groppi, KA Serpa Bioorganic & medicinal chemistry letters 20 (19), 5666-5669, 2010 | 18 | 2010 |
Synthesis of chromanyl and dihydrobenzofuranyl piperazines DA Favor, DS Johnson, JJ Powers, T Li, R Madabattula Tetrahedron Letters 48 (17), 3039-3041, 2007 | 18 | 2007 |
Sulfonamides as selective oestrogen receptor β agonists LR Roberts, D Armor, C Barker, A Bent, K Bess, A Brown, DA Favor, ... Bioorganic & medicinal chemistry letters 21 (19), 5680-5683, 2011 | 15 | 2011 |
Naphthyridines as inhibitors of HPK1 B Chan, N Rajapaksa, M Siu, C Stivala, J Tellis, W Wang, BQ Wei, A Zhou, ... US Patent 10,407,424, 2019 | 10 | 2019 |
Serendipity in drug-discovery: a new series of 2-(benzyloxy) benzamides as TRPM8 antagonists A Brown, D Ellis, DA Favor, T Kirkup, W Klute, M MacKenny, G McMurray, ... Bioorganic & medicinal chemistry letters 23 (22), 6118-6122, 2013 | 10 | 2013 |
Isoquinolines as inhibitors of HPK1 B Chan, J Drobnick, L Gazzard, T Heffron, J Liang, S Malhotra, ... US Patent 11,566,003, 2023 | 6 | 2023 |
Isoquinolines as inhibitors of hpk1 B Chan, J Drobnick, L Gazzard, T Heffron, J Liang, S Malhotra, ... | 6 | 2022 |
Oxazolidinones and methods for the synthesis and use of same AB Smith III, RF Hirschmann, PA Sprengeler, AB Benowitz, DA Favor US Patent 6,034,247, 2000 | 5 | 2000 |