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Mélanie DESBOIS
Mélanie DESBOIS
IGM Biosciences
在 igmbio.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
IL-18 induces PD-1–dependent immunosuppression in cancer
M Terme, E Ullrich, L Aymeric, K Meinhardt, M Desbois, N Delahaye, ...
Cancer research 71 (16), 5393-5399, 2011
4112011
Immune infiltrates are prognostic factors in localized gastrointestinal stromal tumors
S Rusakiewicz, M Semeraro, M Sarabi, M Desbois, C Locher, R Mendez, ...
Cancer research 73 (12), 3499-3510, 2013
3442013
Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer
C Coutzac, JM Jouniaux, A Paci, J Schmidt, D Mallardo, A Seck, ...
Nature communications 11 (1), 2168, 2020
3232020
Single-cell dissection of cellular components and interactions shaping the tumor immune phenotypes in ovarian cancer
M Hornburg, M Desbois, S Lu, Y Guan, AA Lo, S Kaufman, A Elrod, ...
Cancer cell 39 (7), 928-944. e6, 2021
2052021
Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25
D Hannani, M Vetizou, D Enot, S Rusakiewicz, N Chaput, D Klatzmann, ...
Cell research 25 (2), 208-224, 2015
1982015
Integrated digital pathology and transcriptome analysis identifies molecular mediators of T-cell exclusion in ovarian cancer
M Desbois, AR Udyavar, L Ryner, C Kozlowski, Y Guan, M Dürrbaum, ...
Nature communications 11 (1), 5583, 2020
1382020
Cancer-induced immunosuppression: IL-18–elicited immunoablative NK cells
M Terme, E Ullrich, L Aymeric, K Meinhardt, JD Coudert, M Desbois, ...
Cancer research 72 (11), 2757-2767, 2012
1342012
Cancer‐associated fibroblasts: key players in shaping the tumor immune microenvironment
M Desbois, Y Wang
Immunological reviews 302 (1), 241-258, 2021
1192021
IL-15 trans-signaling with the superagonist RLI promotes effector/memory CD8+ T cell responses and enhances antitumor activity of PD-1 antagonists
M Desbois, P Le Vu, C Coutzac, E Marcheteau, C Béal, M Terme, A Gey, ...
The Journal of Immunology 197 (1), 168-178, 2016
572016
Phase I clinical trial combining imatinib mesylate and IL-2: HLA-DR+ NK cell levels correlate with disease outcome
N Chaput, C Flament, C Locher, M Desbois, A Rey, S Rusakiewicz, ...
Oncoimmunology 2 (2), e23080, 2013
422013
Natural killer cells in non-hematopoietic malignancies
M Desbois, S Rusakiewicz, C Locher, L Zitvogel, N Chaput
Frontiers in immunology 3, 395, 2012
412012
IL-15 superagonist RLI has potent immunostimulatory properties on NK cells: Implications for antimetastatic treatment
M Desbois, C Béal, M Charrier, B Besse, G Meurice, N Cagnard, ...
Journal for Immunotherapy of Cancer 8 (1), 2020
332020
Breaking immune tolerance in cancer
M Desbois, S Champiat, N Chaput
Bulletin du Cancer 102 (1), 34-52, 2015
6*2015
Oxazaphosphorines combined with immune checkpoint blockers: dose-dependent tuning between immune and cytotoxic effects
J Delahousse, C Skarbek, M Desbois, JL Perfettini, N Chaput, A Paci
Journal for Immunotherapy of Cancer 8 (2), 2020
42020
Anti-DR5 agonist IgM antibody IGM-8444 combined with SMAC mimetic birinapant induces strong synergistic tumor cytotoxicity
BT Wang, M Desbois, SE Calhoun, TJ Matthew, P Yakkundi, L Wang, ...
Cancer Res. 82, 1068, 2022
22022
Novel combinations of aplitabart, a DR5 agonist IgM antibody, with ADCs or chemotherapeutic agents lead to robust anti-tumor responses in solid tumor models
M Desbois, SE Calhoun, KC Hart, C Denson, P Yakkundi, TJ Matthew, ...
breast 1, 10.6, 2024
12024
IGM-7354, AN ANTI-PD-L1/IL-15 IGM IMMUNOCYTOKINE, ACTIVATES AND EXPANDS NK CELLS AND EFFECTOR MEMORY CD8 (+) T CELLS IN VIVO
M Desbois, T Giffon, P Yakkundi, S Pandey, R Rosete, D Machado, ...
Journal for ImmunoTherapy of Cancer 10, A1260-A1260, 2022
12022
711 IGM-7354 is an anti-PD-L1 IgM antibody and IL-15 cytokine fusion that enhances NK and CD8+ T cell proliferation and tumor cytotoxicity plus potently reverses T cell exhaustion
T Giffon, M Desbois, D Ng, P Yakkundi, M Manlusoc, M Oyasu, R Rosete, ...
Journal for ImmunoTherapy of Cancer 9 (Suppl 2), A740-A740, 2021
12021
Mechanistic evaluation of anti-DR5 IgM antibody IGM-8444 with potent tumor cytotoxicity, without in vitro hepatotoxicity
BT Wang, T Kothambawala, KC Hart, X Chen, M Desbois, SE Calhoun, ...
Proceedings of the American Association for Cancer Research Annual Meeting …, 2021
12021
Reactive stroma mediates CD8+ T cell spatial distribution and function in ovarian cancer
Y Wang, L Ryner, AR Udyavar, M Desbois, C Kozlowski, CW Chang, ...
Annals of Oncology 28, v349, 2017
12017
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