Spread of aggregates after olfactory bulb injection of α-synuclein fibrils is associated with early neuronal loss and is reduced long term NL Rey, S George, JA Steiner, Z Madaj, KC Luk, JQ Trojanowski, ... Acta neuropathologica 135, 65-83, 2018 | 202 | 2018 |
Microglia affect α-synuclein cell-to-cell transfer in a mouse model of Parkinson’s disease S George, NL Rey, T Tyson, C Esquibel, L Meyerdirk, E Schulz, S Pierce, ... Molecular neurodegeneration 14, 1-22, 2019 | 181 | 2019 |
α‐Synuclein: The Long Distance Runner S George, L Rey, Nolwen, N Reichenbach, JA Steiner, P Brundin Brain Pathology 23 (3), 350-357, 2013 | 162 | 2013 |
Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson’s disease A Ghosh, T Tyson, S George, EN Hildebrandt, JA Steiner, Z Madaj, ... Science translational medicine 8 (368), 368ra174-368ra174, 2016 | 160 | 2016 |
Immunotherapy in Parkinson’s disease: micromanaging alpha-synuclein aggregation S George, P Brundin Journal of Parkinson's disease 5 (3), 413-424, 2015 | 105 | 2015 |
α-Synuclein conformational strains spread, seed and target neuronal cells differentially after injection into the olfactory bulb NL Rey, L Bousset, S George, Z Madaj, L Meyerdirk, E Schulz, JA Steiner, ... Acta neuropathologica communications 7, 1-18, 2019 | 93 | 2019 |
Clioquinol improves cognitive, motor function, and microanatomy of the alpha-synuclein hA53T transgenic mice DI Finkelstein, DJ Hare, JL Billings, A Sedjahtera, M Nurjono, E Arthofer, ... ACS Chemical Neuroscience 7 (1), 119-129, 2016 | 86 | 2016 |
α-Synuclein transgenic mice exhibit reduced anxiety-like behaviour S George, M van den Buuse, S San Mok, CL Masters, QX Li, JG Culvenor Experimental neurology 210 (2), 788-792, 2008 | 81 | 2008 |
What’s to like about the prion-like hypothesis for the spreading of aggregated α-synuclein in Parkinson disease? CJR Dunning, S George, P Brundin Prion 7 (1), 92-97, 2013 | 76 | 2013 |
Spreading the word: precise animal models and validated methods are vital when evaluating prion‐like behaviour of alpha‐synuclein NL Rey, S George, P Brundin Neuropathology and applied neurobiology 42 (1), 51-76, 2016 | 71 | 2016 |
Nonsteroidal selective androgen receptor modulators and selective estrogen receptor β agonists moderate cognitive deficits and amyloid-β levels in a mouse model of Alzheimer's … S George, GH Petit, K Gouras, Gunnar, P Brundin, R Olson ACS Chemical Neuroscience, 2013 | 67 | 2013 |
Bacterial butyrate in Parkinson's disease is linked to epigenetic changes and depressive symptoms A Xie, E Ensink, P Li, J Gordevičius, LL Marshall, S George, JA Pospisilik, ... Movement Disorders 37 (8), 1644-1653, 2022 | 66 | 2022 |
Dopamine D2 receptor knockout mice develop features of Parkinson disease RB Tinsley, CR Bye, CL Parish, A Tziotis‐Vais, S George, JG Culvenor, ... Annals of neurology 66 (4), 472-484, 2009 | 55 | 2009 |
α-Synuclein transgenic mice reveal compensatory increases in Parkinson's disease-associated proteins DJ-1 and parkin and have enhanced α-synuclein and PINK1 levels after … S George, SS Mok, M Nurjono, S Ayton, DI Finkelstein, CL Masters, QX Li, ... Journal of molecular neuroscience 42, 243-254, 2010 | 51 | 2010 |
Novel animal model defines genetic contributions for neuron-to-neuron transfer of α-synuclein T Tyson, M Senchuk, JF Cooper, S George, JM Van Raamsdonk, ... Scientific Reports 7 (1), 7506, 2017 | 43 | 2017 |
Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer’s disease S George, A Rönnbäck, GK Gouras, GH Petit, F Grueninger, B Winblad, ... Acta neuropathologica communications 2, 1-8, 2014 | 31 | 2014 |
T cells limit accumulation of aggregate pathology following intrastriatal injection of α-synuclein fibrils S George, T Tyson, NL Rey, R Sheridan, W Peelaerts, K Becker, E Schulz, ... Journal of Parkinson's disease 11 (2), 585-603, 2021 | 28 | 2021 |
Decreased risk of Parkinson’s disease after rheumatoid arthritis diagnosis: a nested case-control study with matched cases and controls J Bacelis, M Compagno, S George, JA Pospisilik, P Brundin, ÅT Naluai, ... Journal of Parkinson's Disease 11 (2), 821-832, 2021 | 20 | 2021 |
Loss of one Engrailed1 allele enhances induced α-synucleinopathy D Chatterjee, DS Sanchez, E Quansah, NL Rey, S George, K Becker, ... Journal of Parkinson's disease 9 (2), 315-326, 2019 | 16 | 2019 |
Urinary tract infections trigger synucleinopathy via the innate immune response W Peelaerts, G Mercado, S George, M Villumsen, A Kasen, M Aguileta, ... Acta neuropathologica 145 (5), 541-559, 2023 | 11 | 2023 |