| High-throughput decoding of antitrypanosomal drug efficacy and resistance S Alsford, S Eckert, N Baker, L Glover, A Sanchez-Flores, KF Leung, ... Nature 482 (7384), 232-236, 2012 | 355 | 2012 |
| Drug resistance in African trypanosomiasis: the melarsoprol and pentamidine story N Baker, HP de Koning, P Mäser, D Horn Trends in parasitology 29 (3), 110-118, 2013 | 311 | 2013 |
| Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes N Baker, L Glover, JC Munday, D Aguinaga Andrés, MP Barrett, ... Proceedings of the National Academy of Sciences 109 (27), 10996-11001, 2012 | 184 | 2012 |
| Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of … JC Munday, AA Eze, N Baker, L Glover, C Clucas, D Aguinaga Andrés, ... Journal of Antimicrobial Chemotherapy 69 (3), 651-663, 2014 | 140 | 2014 |
| Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6 N Baker, S Alsford, D Horn Molecular and biochemical parasitology 176 (1), 55-57, 2011 | 135 | 2011 |
| An Improved Small-Molecule Inhibitor of FtsZ with Superior In Vitro Potency, Drug-Like Properties, and In Vivo Efficacy NR Stokes, N Baker, JM Bennett, J Berry, I Collins, LG Czaplewski, ... Antimicrobial agents and chemotherapy 57 (1), 317-325, 2013 | 113 | 2013 |
| Design, synthesis and structure–activity relationships of substituted oxazole–benzamide antibacterial inhibitors of FtsZ NR Stokes, N Baker, JM Bennett, PK Chauhan, I Collins, DT Davies, ... Bioorganic & medicinal chemistry letters 24 (1), 353-359, 2014 | 94 | 2014 |
| Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival N Baker, CMC Catta-Preta, R Neish, J Sadlova, B Powell, ... Nature communications 12 (1), 1244, 2021 | 75 | 2021 |
| Genetic dissection of drug resistance in trypanosomes SAM Alsford, JM Kelly, N Baker, D Horn Parasitology 140 (12), 1478-1491, 2013 | 69 | 2013 |
| Insights into antitrypanosomal drug mode-of-action from cytology-based profiling JA Thomas, N Baker, S Hutchinson, C Dominicus, A Trenaman, L Glover, ... PLoS neglected tropical diseases 12 (11), e0006980, 2018 | 62 | 2018 |
| Genome-scale RNAi screens for high-throughput phenotyping in bloodstream-form African trypanosomes L Glover, S Alsford, N Baker, DJ Turner, A Sanchez-Flores, S Hutchinson, ... Nature protocols 10 (1), 106-133, 2015 | 60 | 2015 |
| Pentamidine Is Not a Permeant but a Nanomolar Inhibitor of the Trypanosoma brucei Aquaglyceroporin-2 J Song, N Baker, M Rothert, B Henke, L Jeacock, D Horn, E Beitz PLoS pathogens 12 (2), e1005436, 2016 | 56 | 2016 |
| Vacuolar ATPase depletion affects mitochondrial ATPase function, kinetoplast dependency, and drug sensitivity in trypanosomes N Baker, G Hamilton, JM Wilkes, S Hutchinson, MP Barrett, D Horn Proceedings of the National Academy of Sciences 112 (29), 9112-9117, 2015 | 51 | 2015 |
| Chimerization at the AQP2–AQP3 locus is the genetic basis of melarsoprol–pentamidine cross-resistance in clinical Trypanosoma brucei gambiense isolates FE Graf, N Baker, JC Munday, HP De Koning, D Horn, P Mäser International Journal for Parasitology: Drugs and Drug Resistance 5 (2), 65-68, 2015 | 50 | 2015 |
| Aquaglyceroporin-null trypanosomes display glycerol transport defects and respiratory-inhibitor sensitivity L Jeacock, N Baker, N Wiedemar, P Mäser, D Horn PLoS pathogens 13 (3), e1006307, 2017 | 47 | 2017 |
| Comparative genomics of drug resistance in Trypanosoma brucei rhodesiense FE Graf, P Ludin, C Arquint, RS Schmidt, N Schaub, C Kunz Renggli, ... Cellular and molecular life sciences 73, 3387-3400, 2016 | 29 | 2016 |
| Chemogenomic profiling of antileishmanial efficacy and resistance in the related kinetoplastid parasite Trypanosoma brucei CF Collett, C Kitson, N Baker, HB Steele-Stallard, MV Santrot, ... Antimicrobial Agents and Chemotherapy 63 (8), 10.1128/aac. 00795-19, 2019 | 21 | 2019 |
| Repositioning of a diaminothiazole series confirmed to target the cyclin-dependent kinase CRK12 for use in the treatment of African animal trypanosomiasis A Smith, RJ Wall, S Patterson, T Rowan, E Rico Vidal, L Stojanovski, ... Journal of medicinal chemistry 65 (7), 5606-5624, 2022 | 7 | 2022 |
| Evolutionary analysis of cellular reduction and anaerobicity in the hyper-prevalent gut microbe Blastocystis K Záhonová, RS Low, CJ Warren, D Cantoni, EK Herman, L Yiangou, ... Current Biology 33 (12), 2449-2464. e8, 2023 | 5 | 2023 |
| Screening for new natural drugs and drug resistance determinants in African trypanosomiasis NL Baker London School of Hygiene and Tropical Medicine (University of London), 2013 | | 2013 |
