| Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ... Cancer cell 22 (4), 425-437, 2012 | 1963 | 2012 |
| Intertumoral Heterogeneity within Medulloblastoma Subgroups FMG Cavalli, M Remke, L Rampasek, J Peacock, DJH Shih, B Luu, ... Cancer Cell 31 (6), 737-754. e6, 2017 | 1076 | 2017 |
| The whole-genome landscape of medulloblastoma subtypes. PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ... Nature 547 (7663), 311-317, 2017 | 973 | 2017 |
| Subgroup-specific structural variation across 1,000 medulloblastoma genomes PA Northcott, DJH Shih, J Peacock, L Garzia, AS Morrissy, T Zichner, ... Nature 488 (7409), 49, 2012 | 969 | 2012 |
| Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma PA Northcott, C Lee, T Zichner, AM Stütz, S Erkek, D Kawauchi, DJH Shih, ... Nature 511 (7510), 428, 2014 | 682 | 2014 |
| Epigenomic alterations define lethal CIMP-positive ependymomas of infancy SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ... Nature 506 (7489), 445-450, 2014 | 641 | 2014 |
| Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy X Lan, DJ Jörg, FMG Cavalli, LM Richards, LV Nguyen, RJ Vanner, ... Nature 549 (7671), 227-232, 2017 | 434 | 2017 |
| Childhood cerebellar tumours mirror conserved fetal transcriptional programs MC Vladoiu, I El-Hamamy, LK Donovan, H Farooq, BL Holgado, ... Nature 572 (7767), 67-73, 2019 | 367 | 2019 |
| Cytogenetic prognostication within medulloblastoma subgroups DJH Shih, PA Northcott, M Remke, A Korshunov, V Ramaswamy, M Kool, ... Journal of Clinical Oncology 32 (9), 886-896, 2014 | 358 | 2014 |
| Divergent clonal selection dominates medulloblastoma at recurrence AS Morrissy, L Garzia, DJH Shih, S Zuyderduyn, X Huang, P Skowron, ... Nature 529 (7586), 351-357, 2016 | 347 | 2016 |
| Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays V Hovestadt, M Remke, M Kool, T Pietsch, PA Northcott, R Fischer, ... Acta neuropathologica 125 (6), 913-916, 2013 | 316 | 2013 |
| Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes T Sharma, EC Schwalbe, D Williamson, M Sill, V Hovestadt, M Mynarek, ... Acta Neuropathologica 138 (2), 309-326, 2019 | 243 | 2019 |
| Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells G MacLeod, DA Bozek, N Rajakulendran, V Monteiro, M Ahmadi, ... Cell reports 27 (3), 971-986. e9, 2019 | 202 | 2019 |
| Stalled developmental programs at the root of pediatric brain tumors S Jessa, A Blanchet-Cohen, B Krug, M Vladoiu, M Coutelier, D Faury, ... Nature genetics 51 (12), 1702-1713, 2019 | 201 | 2019 |
| TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma M Remke, V Ramaswamy, J Peacock, DJH Shih, C Koelsche, ... Acta neuropathologica 126 (6), 917-929, 2013 | 198 | 2013 |
| Therapeutic impact of cytoreductive surgery and irradiation of posterior fossa ependymoma in the molecular era: a retrospective multicohort analysis V Ramaswamy, T Hielscher, SC Mack, A Lassaletta, T Lin, KW Pajtler, ... Journal of Clinical Oncology 34 (21), 2468-2477, 2016 | 192 | 2016 |
| Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity LM Richards, OKN Whitley, G MacLeod, FMG Cavalli, FJ Coutinho, ... Nature Cancer, 1-17, 2021 | 191 | 2021 |
| Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma LK Donovan, A Delaidelli, SK Joseph, K Bielamowicz, K Fousek, ... Nature Medicine 26 (5), 720-731, 2020 | 176 | 2020 |
| Recurrent non-coding U1-snRNA mutations drive cryptic splicing in Shh medulloblastoma H Suzuki, SA Kumar, S Shuai, A Diaz-Navarro, A Gutierrez-Fernandez, ... Nature 574, 707–711, 2019 | 155 | 2019 |
| Spatial heterogeneity in medulloblastoma AS Morrissy, FMG Cavalli, M Remke, V Ramaswamy, DJH Shih, ... Nature Genetics 49 (5), 780-788, 2017 | 141 | 2017 |
