A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity TM Frayling, NJ Timpson, MN Weedon, E Zeggini, RM Freathy, ... Science 316 (5826), 889-894, 2007 | 5639 | 2007 |
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index EK Speliotes, CJ Willer, SI Berndt, KL Monda, G Thorleifsson, AU Jackson, ... Nature genetics 42 (11), 937-948, 2010 | 3541 | 2010 |
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes E Zeggini, MN Weedon, CM Lindgren, TM Frayling, KS Elliott, H Lango, ... Science 316 (5829), 1336-1341, 2007 | 2618 | 2007 |
Hundreds of variants clustered in genomic loci and biological pathways affect human height H Lango Allen, K Estrada, G Lettre, SI Berndt, MN Weedon, F Rivadeneira, ... Nature 467 (7317), 832-838, 2010 | 2325 | 2010 |
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes E Zeggini, LJ Scott, R Saxena, BF Voight, JL Marchini, T Hu, ... Nature genetics 40 (5), 638-645, 2008 | 2293 | 2008 |
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants 1958 Birth Cohort Controls: Jones Richard W 18 McArdle Wendy L 18 Ring Susan ... Nature genetics 39 (11), 1329-1337, 2007 | 1431 | 2007 |
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution IM Heid, AU Jackson, JC Randall, TW Winkler, L Qi, V Steinthorsdottir, ... Nature genetics 42 (11), 949-960, 2010 | 1097 | 2010 |
Genome-wide association analysis identifies 20 loci that influence adult height MN Weedon, H Lango, CM Lindgren, C Wallace, DM Evans, M Mangino, ... Nature genetics 40 (5), 575-583, 2008 | 994 | 2008 |
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls Nature 464 (7289), 713-720, 2010 | 935 | 2010 |
Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A S Nejentsev, JMM Howson, NM Walker, J Szeszko, SF Field, HE Stevens, ... Nature 450 (7171), 887-892, 2007 | 701 | 2007 |
A genome-wide association study identifies protein quantitative trait loci (pQTLs) D Melzer, JRB Perry, D Hernandez, AM Corsi, K Stevens, I Rafferty, ... PLoS genetics 4 (5), e1000072, 2008 | 551 | 2008 |
Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease SE Flanagan, E Haapaniemi, MA Russell, R Caswell, HL Allen, ... Nature genetics 46 (8), 812-814, 2014 | 516 | 2014 |
A common variant of HMGA2 is associated with adult and childhood height in the general population MN Weedon, G Lettre, RM Freathy, CM Lindgren, BF Voight, JRB Perry, ... Nature genetics 39 (10), 1245-1250, 2007 | 489 | 2007 |
Common variants in WFS1 confer risk of type 2 diabetes MS Sandhu, MN Weedon, KA Fawcett, J Wasson, SL Debenham, A Daly, ... Nature genetics 39 (8), 951-953, 2007 | 472 | 2007 |
Common Variation in the FTO Gene Alters Diabetes-Related Metabolic Traits to the Extent Expected Given Its Effect on BMI RM Freathy, NJ Timpson, DA Lawlor, A Pouta, Y Ben-Shlomo, ... Diabetes 57 (5), 1419-1426, 2008 | 435 | 2008 |
Comprehensive rare variant analysis via whole-genome sequencing to determine the molecular pathology of inherited retinal disease KJ Carss, G Arno, M Erwood, J Stephens, A Sanchis-Juan, S Hull, K Megy, ... The American Journal of Human Genetics 100 (1), 75-90, 2017 | 427 | 2017 |
Whole-genome sequencing of patients with rare diseases in a national health system E Turro, WJ Astle, K Megy, S Gräf, D Greene, O Shamardina, HL Allen, ... Nature 583 (7814), 96-102, 2020 | 412 | 2020 |
The effect of early, comprehensive genomic testing on clinical care in neonatal diabetes: an international cohort study E De Franco, SE Flanagan, JAL Houghton, HL Allen, DJG Mackay, ... The Lancet 386 (9997), 957-963, 2015 | 360 | 2015 |
Improved genetic testing for monogenic diabetes using targeted next-generation sequencing S Ellard, H Lango Allen, E De Franco, SE Flanagan, G Hysenaj, ... Diabetologia 56, 1958-1963, 2013 | 338 | 2013 |
Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk H Lango, UK Type 2 Diabetes Genetics Consortium, CNA Palmer, ... Diabetes 57 (11), 3129-3135, 2008 | 332 | 2008 |