Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE ε2 protective effect in Alzheimer disease R Panitch, J Hu, J Chung, C Zhu, G Meng, W Xia, DA Bennett, KL Lunetta, ... Molecular psychiatry 26 (10), 6054-6064, 2021 | 38 | 2021 |
Monomeric C‐reactive protein via endothelial CD31 for neurovascular inflammation in an ApoE genotype‐dependent pattern: A risk factor for Alzheimer’s disease? Z Zhang, H Na, Q Gan, Q Tao, Y Alekseyev, J Hu, Z Yan, JB Yang, H Tian, ... Aging Cell 20 (11), e13501, 2021 | 37 | 2021 |
scruff: an R/Bioconductor package for preprocessing single-cell RNA-sequencing data Z Wang, J Hu, WE Johnson, JD Campbell BMC bioinformatics 20, 1-9, 2019 | 31 | 2019 |
Blood and brain transcriptome analysis reveals APOE genotype-mediated and immune-related pathways involved in Alzheimer disease R Panitch, J Hu, W Xia, DA Bennett, TD Stein, LA Farrer, GR Jun Alzheimer's research & therapy 14 (1), 30, 2022 | 24 | 2022 |
Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer's disease GR Jun, Y You, C Zhu, G Meng, J Chung, R Panitch, J Hu, W Xia, ... Alzheimer's & Dementia 18 (11), 2042-2054, 2022 | 22 | 2022 |
Identification of circRNAs linked to Alzheimer's disease and related dementias S Puri, J Hu, Z Sun, M Lin, TD Stein, LA Farrer, B Wolozin, X Zhang Alzheimer's & Dementia 19 (8), 3389-3405, 2023 | 21 | 2023 |
Association of mitochondrial variants and haplogroups identified by whole exome sequencing with Alzheimer's disease X Zhang, JJ Farrell, T Tong, J Hu, C Zhu, ... Alzheimer's & Dementia 18 (2), 294-306, 2022 | 15 | 2022 |
Blood and brain transcriptome analysis reveals APOE genotype‑medi‑ated and immune‑related pathways involved in Alzheimer disease. Alzheimers Res Ther 14: 30 R Panitch, J Hu, W Xia, DA Bennett, TD Stein, LA Farrer, GR Jun | 5 | 2022 |
Bulk brain tissue cell-type deconvolution with bias correction for single-nuclei RNA sequencing data using DeTREM NK O’Neill, TD Stein, J Hu, H Rehman, JD Campbell, M Yajima, X Zhang, ... BMC bioinformatics 24 (1), 349, 2023 | 4 | 2023 |
Defining Alzheimer’s disease subtypes using polygenic risk scores integrated with genomic and brain transcriptomic profiles: Genetics/genetic factors of Alzheimer's disease J Hu, J Chung, R Panitch, C Zhu, GW Beecham, J Mez, LA Farrer, ... Alzheimer's & Dementia 16, e046449, 2020 | 3 | 2020 |
Alzheimer's disease heterogeneity explained by polygenic risk scores derived from brain transcriptomic profiles J Chung, N Sahelijo, T Maruyama, J Hu, R Panitch, W Xia, J Mez, ... Alzheimer's & Dementia 19 (11), 5173-5184, 2023 | 2 | 2023 |
Cognitive resilience to Alzheimer's disease characterized by cell‐type abundance N O'Neill, TD Stein, OA Olayinka, JA Empawi, J Hu, T Tong, X Zhang, ... Alzheimer's & Dementia, 2024 | | 2024 |
Single Nucleus RNA Sequencing Reveals Interaction Between Microglia and Endothelial Cells in Mixed Alzheimer’s Disease and Vascular Pathology OA Olayinka, NK O'Neill, JA Empawi, P Bock, J Hu, M Wong, TD Stein, ... Alzheimer's Association International Conference, 2024 | | 2024 |
APOE genotype-specific methylation patterns are linked to Alzheimer disease pathology and estrogen response R Panitch, N Sahelijo, J Hu, K Nho, DA Bennett, KL Lunetta, R Au, ... Translational Psychiatry 14 (1), 129, 2024 | | 2024 |
Precision Medicine in Alzheimer’s Disease: Phenotype Investigation, Medication Effects and Variant Analysis in Cell Type Specific Subgroups EP Tost, F Grenn, J Hu Alzheimer's & Dementia 19, e083103, 2023 | | 2023 |
Differential expression of circRNA in Alzheimer’s disease: Quantitative and Functional Analyses S Puri, J Hu, ML Lin, TD Stein, LA Farrer, X Zhang, B Wolozin Alzheimer's Association International Conference, 2023 | | 2023 |
Predicting Conversion to Alzheimer Disease using Module‐Based Polygenic Risk Scores Informed by Brain Proteome Profiles J Hu, N Sahelijo, D Priyadarshi, PM Thompson, AJ Saykin, C Davatzikos, ... Alzheimer's & Dementia 19, e065314, 2023 | | 2023 |
Bulk brain tissue cell type deconvolution with bias correction for single‐nuclei RNA‐seq NK O'Neill, J Hu, TD Stein, X Zhang, LA Farrer Alzheimer's & Dementia 18, e065942, 2022 | | 2022 |
Bulk and single cell transcriptomic analysis of different dementia types in human hippocampus OA Olayinka, J Hu, NK O'Neill, M Wong, H Rickner, I Simkin, TD Stein, ... Alzheimer's & Dementia 18, e067753, 2022 | | 2022 |
Cell‐Level Transcriptomic Network Analysis Provides Insights into Distinct Biological Mechanisms for Alzheimer’s Disease Enabling Targeted Drug Repositioning N Sahelijo, J Hu, D Priyadarshi, R Panitch, L Shen, PM Thompson, ... Alzheimer's & Dementia 18, e065166, 2022 | | 2022 |