Architecture of eukaryotic mRNA 3′-end processing machinery A Casañal, A Kumar, CH Hill, AD Easter, P Emsley, G Degliesposti, ... Science 358 (6366), 1056-1059, 2017 | 141 | 2017 |
Structure of the Fanconi anaemia monoubiquitin ligase complex S Shakeel, E Rajendra, P Alcón, F O’Reilly, DS Chorev, S Maslen, ... Nature 575 (7781), 234-237, 2019 | 97 | 2019 |
Insights into Hunter syndrome from the structure of iduronate-2-sulfatase M Demydchuk, CH Hill, A Zhou, G Bunkóczi, PE Stein, D Marchesan, ... Nature Communications 8 (1), 15786, 2017 | 89 | 2017 |
Genome-wide dynamics of a bacterial response to antibiotics that target the cell envelope A Hesketh, C Hill, J Mokhtar, G Novotna, N Tran, M Bibb, HJ Hong BMC genomics 12, 1-20, 2011 | 75 | 2011 |
Activation of the endonuclease that defines mRNA 3′ ends requires incorporation into an 8-subunit core cleavage and polyadenylation factor complex CH Hill, V Boreikaitė, A Kumar, A Casañal, P Kubík, G Degliesposti, ... Molecular cell 73 (6), 1217-1231. e11, 2019 | 74 | 2019 |
The intrinsic structure of poly (A) RNA determines the specificity of Pan2 and Caf1 deadenylases TTL Tang, JAW Stowell, CH Hill, LA Passmore Nature structural & molecular biology 26 (6), 433-442, 2019 | 58 | 2019 |
Azasugar inhibitors as pharmacological chaperones for Krabbe disease CH Hill, AH Viuff, SJ Spratley, S Salamone, SH Christensen, RJ Read, ... Chemical science 6 (5), 3075-3086, 2015 | 58 | 2015 |
The mechanism of glycosphingolipid degradation revealed by a GALC-SapA complex structure CH Hill, GM Cook, SJ Spratley, S Fawke, SC Graham, JE Deane Nature communications 9 (1), 151, 2018 | 56 | 2018 |
Structural snapshots illustrate the catalytic cycle of β-galactocerebrosidase, the defective enzyme in Krabbe disease CH Hill, SC Graham, RJ Read, JE Deane Proceedings of the National Academy of Sciences 110 (51), 20479-20484, 2013 | 50 | 2013 |
A novel membrane protein, VanJ, conferring resistance to teicoplanin G Novotna, C Hill, K Vincent, C Liu, HJ Hong Antimicrobial agents and chemotherapy 56 (4), 1784-1796, 2012 | 39 | 2012 |
Molecular mechanisms of disease pathogenesis differ in Krabbe disease variants SJ Spratley, CH Hill, AH Viuff, JR Edgar, K Skjødt, JE Deane Traffic 17 (8), 908-922, 2016 | 37 | 2016 |
Insights into herpesvirus assembly from the structure of the pUL7: pUL51 complex BG Butt, DJ Owen, CM Jeffries, L Ivanova, CH Hill, JW Houghton, ... Elife 9, e53789, 2020 | 36 | 2020 |
Modulation of viral programmed ribosomal frameshifting and stop codon readthrough by the host restriction factor shiftless S Napthine, CH Hill, HCM Nugent, I Brierley Viruses 13 (7), 1230, 2021 | 32 | 2021 |
Structural and molecular basis for Cardiovirus 2A protein as a viral gene expression switch CH Hill, L Pekarek, S Napthine, A Kibe, AE Firth, SC Graham, N Caliskan, ... Nature communications 12 (1), 7166, 2021 | 27 | 2021 |
Characterization of the stimulators of protein-directed ribosomal frameshifting in Theiler's murine encephalomyelitis virus S Napthine, S Bell, CH Hill, I Brierley, AE Firth Nucleic acids research 47 (15), 8207-8223, 2019 | 21 | 2019 |
A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding JAW Stowell, JL Wagstaff, CH Hill, M Yu, SH McLaughlin, SMV Freund, ... Journal of Biological Chemistry 293 (24), 9210-9222, 2018 | 19 | 2018 |
Structure of human saposin A at lysosomal pH CH Hill, RJ Read, JE Deane Acta Crystallographica Section F: Structural Biology Communications 71 (7 …, 2015 | 16 | 2015 |
Investigating molecular mechanisms of 2A-stimulated ribosomal pausing and frameshifting in Theilovirus CH Hill, GM Cook, S Napthine, A Kibe, K Brown, N Caliskan, AE Firth, ... Nucleic acids research 49 (20), 11938-11958, 2021 | 12 | 2021 |
A new family of bacterial ribosome hibernation factors K Helena-Bueno, MY Rybak, CL Ekemezie, R Sullivan, CR Brown, ... Nature 626 (8001), 1125-1132, 2024 | 8 | 2024 |
Insights from structural studies of the cardiovirus 2A protein N Caliskan, CH Hill Bioscience Reports 42 (1), BSR20210406, 2022 | 6 | 2022 |