| X-ray structure of Candida antarctica lipase A shows a novel lid structure and a likely mode of interfacial activation DJ Ericsson, A Kasrayan, P Johansson, T Bergfors, AG Sandström, ... Journal of molecular biology 376 (1), 109-119, 2008 | 267 | 2008 |
| Structural insight into allosteric modulation of protease-activated receptor 2 RKY Cheng, C Fiez-Vandal, O Schlenker, K Edman, B Aggeler, DG Brown, ... Nature 545 (7652), 112-115, 2017 | 252 | 2017 |
| Crystal structures of a poplar xyloglucan endotransglycosylase reveal details of transglycosylation acceptor binding P Johansson, H Brumer III, MJ Baumann, AM Kallas, H Henriksson, ... The Plant Cell 16 (4), 874-886, 2004 | 201 | 2004 |
| Inhibition of the fungal fatty acid synthase type I multienzyme complex P Johansson, B Wiltschi, P Kumari, B Kessler, C Vonrhein, J Vonck, ... Proceedings of the National Academy of Sciences 105 (35), 12803-12808, 2008 | 139 | 2008 |
| Crystal structure of microsomal prostaglandin E2 synthase provides insight into diversity in the MAPEG superfamily T Sjögren, J Nord, M Ek, P Johansson, G Liu, S Geschwindner Proceedings of the National Academy of Sciences 110 (10), 3806-3811, 2013 | 132 | 2013 |
| Ligand binding thermodynamics in drug discovery: still a hot tip? S Geschwindner, J Ulander, P Johansson Journal of Medicinal Chemistry 58 (16), 6321-6335, 2015 | 117 | 2015 |
| MraY–antibiotic complex reveals details of tunicamycin mode of action JK Hakulinen, J Hering, G Brändén, H Chen, A Snijder, M Ek, ... Nature chemical biology 13 (3), 265-267, 2017 | 116 | 2017 |
| Enzymatic properties of native and deglycosylated hybrid aspen (Populus tremula×tremuloides) xyloglucan endotransglycosylase 16A expressed in Pichia pastoris ÅM Kallas, K Piens, SE Denman, H Henriksson, J Fäldt, P Johansson, ... Biochemical Journal 390 (1), 105-113, 2005 | 90 | 2005 |
| New aminoimidazoles as β-secretase (BACE-1) inhibitors showing amyloid-β (Aβ) lowering in brain Y Gravenfors, J Viklund, J Blid, T Ginman, S Karlström, J Kihlström, ... Journal of medicinal chemistry 55 (21), 9297-9311, 2012 | 75 | 2012 |
| Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus L Odqvist, Z Jevnikar, R Riise, L Öberg, M Rhedin, D Leonard, L Yrlid, ... Annals of the Rheumatic Diseases 78 (10), 1363-1370, 2019 | 69 | 2019 |
| Core refinement toward permeable β-secretase (BACE-1) inhibitors with low hERG activity T Ginman, J Viklund, J Malmström, J Blid, R Emond, R Forsblom, ... Journal of Medicinal Chemistry 56 (11), 4181-4205, 2013 | 57 | 2013 |
| Structure of an atypical epoxide hydrolase from Mycobacterium tuberculosis gives insights into its function P Johansson, T Unge, A Cronin, M Arand, T Bergfors, TA Jones, ... Journal of molecular biology 351 (5), 1048-1056, 2005 | 57 | 2005 |
| Dodecin is the key player in flavin homeostasis of archaea M Grininger, H Staudt, P Johansson, J Wachtveitl, D Oesterhelt Journal of biological chemistry 284 (19), 13068-13076, 2009 | 56 | 2009 |
| Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase P Johansson, B Mulinacci, C Koestler, R Vollrath, D Oesterhelt, ... Structure 17 (8), 1063-1074, 2009 | 54 | 2009 |
| Structural and biochemical characterization of a halophilic archaeal alkaline phosphatase A Wende, P Johansson, R Vollrath, M Dyall-Smith, D Oesterhelt, ... Journal of Molecular Biology 400 (1), 52-62, 2010 | 38 | 2010 |
| Rv0216, a conserved hypothetical protein from Mycobacterium tuberculosis that is essential for bacterial survival during infection, has a double hotdog fold A Castell, P Johansson, T Unge, TA Jones, K Bäckbro Protein science 14 (7), 1850-1862, 2005 | 35 | 2005 |
| Mining natural products for macrocycles to drug difficult targets F Begnini, V Poongavanam, B Over, M Castaldo, S Geschwindner, ... Journal of Medicinal Chemistry 64 (2), 1054-1072, 2020 | 34 | 2020 |
| Toward β-secretase-1 inhibitors with improved isoform selectivity P Johansson, K Kaspersson, IK Gurrell, E Bäck, S Eketjäll, CW Scott, ... Journal of Medicinal Chemistry 61 (8), 3491-3502, 2018 | 32 | 2018 |
| Structure and biophysical characterization of the human full-length neurturin–GFRa2 complex: A role for heparan sulfate in signaling J Sandmark, G Dahl, L Öster, B Xu, P Johansson, T Akerud, A Aagaard, ... Journal of Biological Chemistry 293 (15), 5492-5508, 2018 | 30 | 2018 |
| FAM3B PANDER and FAM3C ILEI represent a distinct class of signaling molecules with a non-cytokine-like fold P Johansson, J Bernström, T Gorman, L Öster, S Bäckström, F Schweikart, ... Structure 21 (2), 306-313, 2013 | 30 | 2013 |
