| IL‐17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL‐17F, and implications for receptor binding SG Hymowitz, EH Filvaroff, JP Yin, J Lee, L Cai, P Risser, M Maruoka, ... The EMBO journal, 2001 | 708 | 2001 |
| Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies K Newton, ML Matsumoto, IE Wertz, DS Kirkpatrick, JR Lill, J Tan, ... Cell 134 (4), 668-678, 2008 | 656 | 2008 |
| High Level Escherichia coli Expression and Production of a Bivalent Humanized Antibody Fragment P Carter, RF Kelley, ML Rodrigues, B Snedecor, M Covarrubias, ... Bio/technology 10 (2), 163-167, 1992 | 631 | 1992 |
| Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5 SG Hymowitz, HW Christinger, G Fuh, M Ultsch, M O'Connell, RF Kelley, ... Molecular cell 4 (4), 563-571, 1999 | 601 | 1999 |
| K11-linked polyubiquitination in cell cycle control revealed by a K11 linkage-specific antibody ML Matsumoto, KE Wickliffe, KC Dong, C Yu, I Bosanac, D Bustos, L Phu, ... Molecular cell 39 (3), 477-484, 2010 | 474 | 2010 |
| Tween protects recombinant human growth hormone against agitation‐induced damage via hydrophobic interactions NB Bam, JL Cleland, J Yang, MC Manning, JF Carpenter, RF Kelley, ... Journal of pharmaceutical sciences 87 (12), 1554-1559, 1998 | 395 | 1998 |
| A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL SG Hymowitz, MP O'Connell, MH Ultsch, A Hurst, K Totpal, A Ashkenazi, ... Biochemistry 39 (4), 633-640, 2000 | 366 | 2000 |
| Receptor-selective mutants of apoptosis-inducing ligand 2/tumor necrosis factor-related apoptosis-inducing ligand reveal a greater contribution of death receptor (DR) 5 than … RF Kelley, K Totpal, SH Lindstrom, M Mathieu, K Billeci, L DeForge, R Pai, ... Journal of Biological Chemistry 280 (3), 2205-2212, 2005 | 321 | 2005 |
| Tissue factor: an enzyme cofactor and a true receptor JH Morrissey Thrombosis and haemostasis 86 (07), 66-74, 2001 | 313 | 2001 |
| Superior in vivo efficacy of afucosylated trastuzumab in the treatment of HER2-amplified breast cancer TT Junttila, K Parsons, C Olsson, Y Lu, Y Xin, J Theriault, L Crocker, ... Cancer research 70 (11), 4481-4489, 2010 | 298 | 2010 |
| FAB Assembly and Enrichment in a Monovalent Phage Display System LJ Garrard, M Yang, MP O'Connell, RF Kelley, DJ Henner Bio/technology 9 (12), 1373-1377, 1991 | 266 | 1991 |
| Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding SG Hymowitz, DR Patel, HJA Wallweber, S Runyon, M Yan, JP Yin, ... Journal of Biological Chemistry 280 (8), 7218-7227, 2005 | 240 | 2005 |
| A strategy for risk mitigation of antibodies with fast clearance I Hötzel, FP Theil, LJ Bernstein, S Prabhu, R Deng, L Quintana, J Lutman, ... MAbs 4 (6), 753-760, 2012 | 238 | 2012 |
| Thermodynamic analysis of an antibody functional epitope RF Kelley, MP O'Connell Biochemistry 32 (27), 6828-6835, 1993 | 237 | 1993 |
| In silico selection of therapeutic antibodies for development: viscosity, clearance, and chemical stability VK Sharma, TW Patapoff, B Kabakoff, S Pai, E Hilario, B Zhang, C Li, ... Proceedings of the National Academy of Sciences 111 (52), 18601-18606, 2014 | 230 | 2014 |
| Role of tissue factor in metastasis: functions of the cytoplasmic and extracellular domains of the molecule ME Bromberg, R Sundaram, RJ Homer, A Garen, WH Konigsberg Thrombosis and haemostasis 82 (07), 88-92, 1999 | 200 | 1999 |
| Structure of the extracellular domain of human tissue factor: location of the factor VIIa binding site YA Muller, MH Ultsch, RF Kelley, AM de Vos Biochemistry 33 (36), 10864-10870, 1994 | 193 | 1994 |
| Structural basis of signaling blockade by anti-IL-13 antibody lebrikizumab M Ultsch, J Bevers, G Nakamura, R Vandlen, RF Kelley, LC Wu, ... Journal of molecular biology 425 (8), 1330-1339, 2013 | 170 | 2013 |
| Antitumor efficacy of a bispecific antibody that targets HER2 and activates T cells TT Junttila, J Li, J Johnston, M Hristopoulos, R Clark, D Ellerman, ... Cancer research 74 (19), 5561-5571, 2014 | 162 | 2014 |
| Anti-CD3 antibodies and methods of use X Chen, MS Dennis, AJ Ebens Jr, RF Kelley, MA Mathieu US Patent 10,174,124, 2019 | 155 | 2019 |
