Cytochrome c oxidase activity is a metabolic checkpoint that regulates cell fate decisions during T cell activation and differentiation TN Tarasenko, SE Pacheco, MK Koenig, J Gomez-Rodriguez, ... Cell metabolism 25 (6), 1254-1268. e7, 2017 | 143 | 2017 |
Cortical actin recovery at the immunological synapse leads to termination of lytic granule secretion in cytotoxic T lymphocytes AT Ritter, SM Kapnick, S Murugesan, PL Schwartzberg, GM Griffiths, ... Proceedings of the National Academy of Sciences 114 (32), E6585-E6594, 2017 | 99 | 2017 |
Discoidin domain receptor 2 regulates neutrophil chemotaxis in 3D collagen matrices PV Afonso, CP McCann, SM Kapnick, CA Parent Blood, The Journal of the American Society of Hematology 121 (9), 1644-1650, 2013 | 79 | 2013 |
The emerging role of immune dysfunction in mitochondrial diseases as a paradigm for understanding immunometabolism SM Kapnick, SE Pacheco, PJ McGuire Metabolism 81, 97-112, 2018 | 59 | 2018 |
Inducible T cell kinase regulates the acquisition of cytolytic capacity and degranulation in CD8+ CTLs SM Kapnick, JC Stinchcombe, GM Griffiths, PL Schwartzberg The Journal of Immunology 198 (7), 2699-2711, 2017 | 53 | 2017 |
Mitochondrial physiology C Gourlay bioenergetic communications 1 (1), 1-44, 2020 | 51 | 2020 |
Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1 E Ruffo, V Malacarne, SE Larsen, R Das, L Patrussi, C Wülfing, C Biskup, ... Science translational medicine 8 (321), 321ra7-321ra7, 2016 | 49 | 2016 |
Application of bioluminescence imaging to the prediction of lethality in vaccinia virus-infected mice M Zaitseva, SM Kapnick, J Scott, LR King, J Manischewitz, L Sirota, ... Journal of virology 83 (20), 10437-10447, 2009 | 46 | 2009 |
Genetic Defects in Phosphoinositide 3-Kinase δ Influence CD8+ T Cell Survival, Differentiation, and Function JL Cannons, S Preite, SM Kapnick, G Uzel, PL Schwartzberg Frontiers in Immunology 9, 1758, 2018 | 34 | 2018 |
Polyclonal antibody cocktails generated using DNA vaccine technology protect in murine models of orthopoxvirus disease JW Golden, M Zaitseva, S Kapnick, RW Fisher, MG Mikolajczyk, ... Virology journal 8, 1-19, 2011 | 28 | 2011 |
New tuberculosis drug development: targeting the shikimate pathway SM Kapnick, Y Zhang Expert Opinion on Drug Discovery 3 (5), 565-577, 2008 | 26 | 2008 |
Mapping the mechanical and immunological profiles of polymeric microneedles to enable vaccine and immunotherapy applications SA Shah, RS Oakes, SM Kapnick, CM Jewell Frontiers in immunology 13, 843355, 2022 | 20 | 2022 |
Passive immunotherapies protect WRvFire and IHD-J-Luc vaccinia virus-infected mice from lethality by reducing viral loads in the upper respiratory tract and internal organs M Zaitseva, SM Kapnick, CA Meseda, E Shotwell, LR King, ... Journal of virology 85 (17), 9147-9158, 2011 | 19 | 2011 |
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory JL Cannons, AV Villarino, SM Kapnick, S Preite, HY Shih, ... Cell reports 37 (2), 2021 | 15 | 2021 |
The nanoparticle-enabled success of COVID-19 mRNA vaccines and the promise of microneedle platforms for pandemic vaccine response SM Kapnick DNA and Cell Biology 41 (1), 25-29, 2022 | 14 | 2022 |
Exploiting rational assembly to map distinct roles of regulatory cues during autoimmune therapy RS Oakes, LH Tostanoski, SM Kapnick, E Froimchuk, SK Black, X Zeng, ... ACS nano 15 (3), 4305-4320, 2021 | 14 | 2021 |
Biophysical properties of self-assembled immune signals impact signal processing and the nature of regulatory immune function E Froimchuk, RS Oakes, SM Kapnick, AA Yanes, CM Jewell Nano letters 21 (9), 3762-3771, 2021 | 12 | 2021 |
Measurements of vaccinia virus dissemination using whole body imaging: approaches for predicting of lethality in challenge models and testing of vaccines and antiviral treatments M Zaitseva, S Kapnick, H Golding Vaccinia Virus and Poxvirology: Methods and Protocols, 161-176, 2012 | 11 | 2012 |
Self‐Assembly of Immune Signals to Program Innate Immunity through Rational Adjuvant Design ML Bookstaver, Q Zeng, RS Oakes, SM Kapnick, V Saxena, C Edwards, ... Advanced Science 10 (1), 2202393, 2023 | 10 | 2023 |
Mitochondrial disease disrupts hepatic allostasis and lowers the threshold for immune-mediated liver toxicity M Jestin, SM Kapnick, TN Tarasenko, CT Burke, PM Zerfas, F Diaz, ... Molecular Metabolism 37, 100981, 2020 | 9 | 2020 |