The crystal structure of a triacylglycerol lipase from Pseudomonas cepacia reveals a highly open conformation in the absence of a bound inhibitor KK Kim, HK Song, DH Shin, KY Hwang, SW Suh Structure 5 (2), 173-185, 1997 | 431 | 1997 |
Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules BJ Sung, K Yeon Hwang, Y Ho Jeon, JI Lee, YS Heo, J Hwan Kim, ... Nature 425 (6953), 98-102, 2003 | 332 | 2003 |
Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125 YS Heo, SK Kim, CI Seo, YK Kim, BJ Sung, HS Lee, JI Lee, SY Park, ... The EMBO journal 23 (11), 2185-2195, 2004 | 306 | 2004 |
High-resolution crystal structure of the non-specific lipid-transfer protein from maize seedlings DH Shin, JY Lee, KY Hwang, KK Kim, SW Suh Structure 3 (2), 189-199, 1995 | 268 | 1995 |
Structural basis for cold adaptation: sequence, biochemical properties, and crystal structure of malate dehydrogenase from a psychrophile Aquaspirillium arcticum SY Kim, KY Hwang, SH Kim, HC Sung, YS Han, Y Cho Journal of Biological Chemistry 274 (17), 11761-11767, 1999 | 233 | 1999 |
The crystal structure of flap endonuclease-1 from Methanococcus jannaschii KY Hwang, K Baek, HY Kim, Y Cho Nature structural biology 5 (8), 707-713, 1998 | 207 | 1998 |
Structure-based identification of a novel NTPase from Methanococcus jannaschii KY Hwang, JH Chung, SH Kim, YS Han, Y Cho Nature structural biology 6 (7), 691-696, 1999 | 164 | 1999 |
Rice non-specific lipid transfer protein: the 1.6 Å crystal structure in the unliganded state reveals a small hydrophobic cavity JY Lee, K Min, H Cha, DH Shin, KY Hwang, SW Suh Journal of molecular biology 276 (2), 437-448, 1998 | 159 | 1998 |
Crystal structure of carboxylesterase from Pseudomonas fluorescens, an α/β hydrolase with broad substrate specificity KK Kim, HK Song, DH Shin, KY Hwang, S Choe, OJ Yoo, SW Suh Structure 5 (12), 1571-1584, 1997 | 144 | 1997 |
The natural carotenoid astaxanthin, a PPAR‐α agonist and PPAR‐γ antagonist, reduces hepatic lipid accumulation by rewiring the transcriptome in lipid‐loaded hepatocytes Y Jia, JY Kim, HJ Jun, SJ Kim, JH Lee, MH Hoang, KY Hwang, SJ Um, ... Molecular nutrition & food research 56 (6), 878-888, 2012 | 132 | 2012 |
Structure and mechanism of glutamate racemase from Aquifex pyrophilus KY Hwang, CS Cho, SS Kim, HC Sung, YG Yu, Y Cho Nature structural biology 6 (5), 422-426, 1999 | 124 | 1999 |
Structural basis for the NAD-dependent deacetylase mechanism of Sir2 JH Chang, HC Kim, KY Hwang, JW Lee, SP Jackson, SD Bell, Y Cho Journal of Biological Chemistry 277 (37), 34489-34498, 2002 | 123 | 2002 |
Ursolic acid is a PPAR-α agonist that regulates hepatic lipid metabolism Y Jia, MJH Bhuiyan, H Jun, JH Lee, MH Hoang, HJ Lee, N Kim, D Lee, ... Bioorganic & medicinal chemistry letters 21 (19), 5876-5880, 2011 | 105 | 2011 |
Crystal structure of thermostable α-amylase from Bacillus licheniformis refined at 1.7 Å resolution KY Hwang, HK Song, C Chang, J Lee, SY Lee, KK Kim, S Choe, ... Molecules and cells 7 (2), 251-258, 1997 | 104 | 1997 |
Structural studies of human brain-type creatine kinase complexed with the ADP–Mg2+–NO3−–creatine transition-state analogue complex SM Bong, JH Moon, KH Nam, KS Lee, YM Chi, KY Hwang FEBS letters 582 (28), 3959-3965, 2008 | 103 | 2008 |
Cyanidin is an agonistic ligand for peroxisome proliferator-activated receptor-alpha reducing hepatic lipid Y Jia, JY Kim, H Jun, SJ Kim, JH Lee, MH Hoang, HS Kim, HI Chang, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2013 | 91 | 2013 |
Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction JH Kim, C Lee, M Lee, H Wang, K Kim, SJ Park, I Yoon, J Jang, H Zhao, ... Nature communications 8 (1), 732, 2017 | 86 | 2017 |
Crystallization, molecular replacement solution, and refinement of tetrameric β‐amylase from sweet potato CG Cheong, SH Eom, C Chang, DH Shin, HK Song, K Min, JH Moon, ... Proteins: Structure, Function, and Bioinformatics 21 (2), 105-117, 1995 | 81 | 1995 |
Interactions causing the kinetic trap in serpin protein folding H Im, MS Woo, KY Hwang, MH Yu Journal of Biological Chemistry 277 (48), 46347-46354, 2002 | 80 | 2002 |
Glucose-dependent control of leucine metabolism by leucyl-tRNA synthetase 1 I Yoon, M Nam, HK Kim, HS Moon, S Kim, J Jang, JA Song, SJ Jeong, ... Science 367 (6474), 205-210, 2020 | 72 | 2020 |