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Si Yi Zhang
Si Yi Zhang
在 pfizer.com 的电子邮件经过验证
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引用次数
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Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal
EM Pietras, C Mirantes-Barbeito, S Fong, D Loeffler, LV Kovtonyuk, ...
Nature cell biology 18 (6), 607-618, 2016
6862016
Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis
A Hérault, M Binnewies, S Leong, FJ Calero-Nieto, SY Zhang, YA Kang, ...
Nature 544 (7648), 53-58, 2017
2072017
Stromal niche inflammation mediated by IL-1 signalling is a targetable driver of haematopoietic ageing
CA Mitchell, EV Verovskaya, FJ Calero-Nieto, OC Olson, JW Swann, ...
Nature cell biology 25 (1), 30-41, 2023
972023
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions
TT Ho, PV Dellorusso, EV Verovskaya, ST Bakker, J Flach, LK Smith, ...
Journal of Experimental Medicine 218 (7), e20210223, 2021
802021
Secretory MPP3 reinforce myeloid differentiation trajectory and amplify myeloid cell production
YA Kang, H Paik, SY Zhang, JJ Chen, OC Olson, CA Mitchell, A Collins, ...
Journal of Experimental Medicine 220 (8), e20230088, 2023
162023
Inflammatory changes in the bone marrow microenvironment drive both niche and blood system remodeling during aging
E Verovskaya, F Calero-Nieto, D Reynaud, SY Zhang, A Herault, ...
Experimental Hematology 64, S43-S44, 2018
42018
Stromal inflammation is a targetable driver of hematopoietic aging
EV Verovskaya, CA Mitchell, FJ Calero-Nieto, A Hérault, PV Dellorusso, ...
Biorxiv, 2021.03. 08.434485, 2021
32021
Bone marrow stromal cell remodeling is a common feature of diverse fibrotic myeloproliferative neoplasm models
TB Campbell, SY Zhang, A Valencia, E Passegue
Blood 128 (22), 25, 2016
22016
WINNER I
YA Kang, J Chen, H Paik, S Zhang, M Warr, R Fan, E Passegué
11983
Stromal inflammation is a targetable driver of hematopoietic aging
C Mitchell, E Verovskaya, F Calero-Nieto, O Olson, X Wang, A Herault, ...
2021
SECRETORY MPP3 ENFORCE MYELOID DIFFERENTIATION TRAJECTORY AND AMPLIFY MYELOID CELL PRODUCTION
YA Kang, H Paik, SY Zhang, J Chen, M Warr, R Fan, E Passegue
EXPERIMENTAL HEMATOLOGY 100, S52-S52, 2021
2021
The Functional Interplay Between PTEN and PDK1 in Acute Leukemia
SY Zhang
King's College London, 2021
2021
PTEN-Mediated Leukemogenesis Bypasses Normal Requirement for PDK1 to Activate Downstream PI3K Pathway as Mechanism of Cancer Survival in A Lineage-Specific Manner
SY Zhang, H Lekgetho, V Calleja, P Parker, CWE So
Experimental Hematology 64, S113, 2018
2018
Myeloid-biased multipotent progenitors are secretory cells that control myelopoiesis
YA Kang, J Chen, H Paik, S Zhang, M Warr, R Fan, E Passegué
Experimental Hematology 53, S44, 2017
2017
Myeloid progenitor cluster formation drives regenerative and leukemic myelopoiesis
A Herault, M Binnewies, S Leong, F Calero, SY Zhang, E Pietras, H Chu, ...
Experimental Hematology 44 (9), S79-S80, 2016
2016
Remodeling of the multipotent progenitor (MPP) pool directly contributes to blood aging
E Verovskaya, D Reynaud, S Bakker, SY Zhang, T Ho, E Pietras, ...
Experimental Hematology 44 (9), S54, 2016
2016
The PRO-inflammatory cytokine interleukin-1 is a key regulator of hematopoietic Stem cell fate and function
E Pietras, C Mirantes-Barbeito, S Fong, D Loeffler, L Kovtonyuk, ...
Experimental Hematology 44 (9), S49, 2016
2016
Targeting the fibrotic bone marrow niche for treatment of myeloproliferative neoplasms
T Campbell, SY Zhang, A Valencia, E Passegue
Experimental Hematology 44 (9), S109, 2016
2016
Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal.
E Passegue, EM Pietras, C Mirantes-Barbeito, S Fong, D Loeffler, ...
2016
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