A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster JFW Chan, S Yuan, KH Kok, KKW To, H Chu, J Yang, F Xing, J Liu, ... The lancet 395 (10223), 514-523, 2020 | 11824 | 2020 |
Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan JFW Chan, KH Kok, Z Zhu, H Chu, KKW To, S Yuan, KY Yuen Emerging microbes & infections 9 (1), 221-236, 2020 | 3812 | 2020 |
Simulation of the clinical and pathological manifestations of coronavirus disease 2019 (COVID-19) in a golden Syrian hamster model: implications for disease pathogenesis and … JFW Chan, AJ Zhang, S Yuan, VKM Poon, CCS Chan, ACY Lee, ... Clinical infectious diseases 71 (9), 2428-2446, 2020 | 1210 | 2020 |
Zoonotic origins of human coronaviruses ZW Ye, S Yuan, KS Yuen, SY Fung, CP Chan, DY Jin International journal of biological sciences 16 (10), 1686, 2020 | 1151 | 2020 |
Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory … H Chu, JFW Chan, TTT Yuen, H Shuai, S Yuan, Y Wang, B Hu, CCY Yip, ... The Lancet Microbe 1 (1), e14-e23, 2020 | 862 | 2020 |
Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19 H Chu, JFW Chan, Y Wang, TTT Yuen, Y Chai, Y Hou, H Shuai, D Yang, ... Clinical Infectious Diseases 71 (6), 1400-1409, 2020 | 737 | 2020 |
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing L Riva, S Yuan, X Yin, L Martin-Sancho, N Matsunaga, L Pache, ... Nature 586 (7827), 113-119, 2020 | 735 | 2020 |
COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing KK To, IF Hung, JD Ip, AW Chu, WM Chan, AR Tam, CH Fong, S Yuan, ... Clin infect dis 10, 2020 | 706 | 2020 |
Severe acute respiratory syndrome coronavirus ORF3a protein activates the NLRP3 inflammasome by promoting TRAF3-dependent ubiquitination of ASC KL Siu, KS Yuen, C Castaño-Rodriguez, ZW Ye, ML Yeung, SY Fung, ... The FASEB Journal 33 (8), 8865, 2019 | 537 | 2019 |
Attenuated replication and pathogenicity of SARS-CoV-2 B. 1.1. 529 Omicron H Shuai, JFW Chan, B Hu, Y Chai, TTT Yuen, F Yin, X Huang, C Yoon, ... Nature 603 (7902), 693-699, 2022 | 530 | 2022 |
Coronavirus disease 2019 (COVID-19) re-infection by a phylogenetically distinct severe acute respiratory syndrome coronavirus 2 strain confirmed by whole genome sequencing KKW To, IFN Hung, JD Ip, AWH Chu, WM Chan, AR Tam, CHY Fong, ... Clinical Infectious Diseases 73 (9), e2946-e2951, 2021 | 316 | 2021 |
& Yuen, KY (2020). A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster JFW Chan, S Yuan, KH Kok, KKW To, H Chu, J Yang, F Xing, J Liu, ... The lancet 395 (10223), 514-523, 0 | 302 | |
Surgical mask partition reduces the risk of noncontact transmission in a golden Syrian hamster model for coronavirus disease 2019 (COVID-19) JFW Chan, S Yuan, AJ Zhang, VKM Poon, CCS Chan, ACY Lee, Z Fan, ... Clinical infectious diseases 71 (16), 2139-2149, 2020 | 292 | 2020 |
Characterization of the lipidomic profile of human coronavirus-infected cells: implications for lipid metabolism remodeling upon coronavirus replication B Yan, H Chu, D Yang, KH Sze, PM Lai, S Yuan, H Shuai, Y Wang, ... Viruses 11 (1), 73, 2019 | 262 | 2019 |
Differentiated human airway organoids to assess infectivity of emerging influenza virus J Zhou, C Li, N Sachs, MC Chiu, BHY Wong, H Chu, VKM Poon, D Wang, ... Proceedings of the National Academy of Sciences 115 (26), 6822-6827, 2018 | 259 | 2018 |
SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target S Yuan, H Chu, JFW Chan, ZW Ye, L Wen, B Yan, PM Lai, KM Tee, ... Nature communications 10 (1), 120, 2019 | 235 | 2019 |
Attenuated interferon and proinflammatory response in SARS-CoV-2–infected human dendritic cells is associated with viral antagonism of STAT1 phosphorylation D Yang, H Chu, Y Hou, Y Chai, H Shuai, ACY Lee, X Zhang, Y Wang, ... The Journal of infectious diseases 222 (5), 734-745, 2020 | 195 | 2020 |
Clofazimine broadly inhibits coronaviruses including SARS-CoV-2 S Yuan, X Yin, X Meng, JFW Chan, ZW Ye, L Riva, L Pache, CCY Chan, ... Nature 593 (7859), 418-423, 2021 | 186 | 2021 |
Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells H Chu, CM Chan, X Zhang, Y Wang, S Yuan, J Zhou, RKH Au-Yeung, ... Journal of Biological Chemistry 293 (30), 11709-11726, 2018 | 178 | 2018 |
Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters S Yuan, R Wang, JFW Chan, AJ Zhang, T Cheng, KKH Chik, ZW Ye, ... Nature microbiology 5 (11), 1439-1448, 2020 | 177 | 2020 |