| Neuroprotective effect of resveratrol against brain ischemia reperfusion injury in rats entails reduction of DJ-1 protein expression and activation of PI3K/Akt/GSK3b survival … GA Abdel-Aleem, EF Khaleel, DG Mostafa, LK Elberier Archives of physiology and biochemistry 122 (4), 200-213, 2016 | 87 | 2016 |
| Resveratrol improves high-fat diet induced fatty liver and insulin resistance by concomitantly inhibiting proteolytic cleavage of sterol regulatory element-binding proteins … EF Khaleel, GA Abdel-Aleem, DG Mostafa Canadian journal of physiology and pharmacology 96 (2), 145-157, 2018 | 42 | 2018 |
| Rutin hydrate inhibits apoptosis in the brains of cadmium chloride-treated rats via preserving the mitochondrial integrity and inhibiting endoplasmic reticulum stress DG Mostafa, EF Khaleel, RM Badi, GA Abdel-Aleem, HM Abdeen Neurological research 41 (7), 594-608, 2019 | 38 | 2019 |
| Altered cell to cell communication, autophagy and mitochondrial dysfunction in a model of hepatocellular carcinoma: Potential protective effects of curcumin and stem cell therapy OM Tork, EF Khaleel, OM Abdelmaqsoud Asian Pacific Journal of Cancer Prevention 16 (18), 8271-8279, 2016 | 28 | 2016 |
| Rutin hydrate ameliorates cadmium chloride-induced spatial memory loss and neural apoptosis in rats by enhancing levels of acetylcholine, inhibiting JNK and ERK1/2 activation … GA Abdel-Aleem, EF Khaleel Archives of Physiology and Biochemistry 124 (4), 367-377, 2018 | 26 | 2018 |
| Discovery of sulfonamide-tethered isatin derivatives as novel anticancer agents and VEGFR-2 inhibitors MA Shaldam, H Almahli, A Angeli, RM Badi, EF Khaleel, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2203389, 2023 | 25 | 2023 |
| Novel 4-(2-arylidenehydrazineyl) thienopyrimidine derivatives as anticancer EGFR inhibitors: Design, synthesis, biological evaluation, kinome selectivity and in silico insights HA Elsebaie, EA El-Bastawissy, KM Elberembally, EF Khaleel, RM Badi, ... Bioorganic Chemistry 140, 106799, 2023 | 23 | 2023 |
| Obestatin protects and reverses nonalcoholic fatty liver disease and its associated insulin resistance in rats via inhibition of food intake, enhancing hepatic adiponectin … EF Khaleel, GA Abdel-Aleem Archives of Physiology and Biochemistry 125 (1), 64-78, 2019 | 23 | 2019 |
| Resveratrol protects against hepatic insulin resistance in a rat's model of non‐alcoholic fatty liver disease by down‐regulation of GPAT‐1 and DGAT 2 expression and inhibition … RM Badi, DG Mostafa, EF Khaleel, HH Satti Clinical and Experimental Pharmacology and Physiology 46 (6), 545-555, 2019 | 19 | 2019 |
| Discovery of novel pyridazine-tethered sulfonamides as carbonic anhydrase II inhibitors for the management of glaucoma HO Tawfik, MM Saleh, A Ammara, EF Khaleel, R Badi, YTT Khater, ... Journal of Medicinal Chemistry 67 (2), 1611-1623, 2024 | 11 | 2024 |
| Exendin‐4 exhibits a tumour suppressor effect in SKOVR‐3 and OVACR‐3 ovarian cancer cells lines by the activation of SIRT1 and inhibition of NF‐κB EF Khaleel, RM Badi, HH Satti, DG Mostafa Clinical and Experimental Pharmacology and Physiology 47 (6), 1092-1102, 2020 | 11 | 2020 |
| Inhibition of the hepatic glucose output is responsible for the hypoglycemic effect of Crataegus aronia against type 2 diabetes mellitus in rats DG Mostafa, EF Khaleel, GA Abdel-Aleem Archives of Biological Sciences 70 (2), 277-287, 2018 | 9 | 2018 |
| Remedial effects of vitamin E and L-arginine on peripheral neuropathy in streptozotocin-induced diabetic rats I Bin-Jaliah, S El-Attar, EF Khaleel, LA El-Sayed, MA Haidara American Journal of Pharmacology and Toxicology 9 (1), 13, 2014 | 9 | 2014 |
| Identification of new anti-mycobacterial agents based on quinoline-isatin hybrids targeting enoyl acyl carrier protein reductase (InhA) EF Khaleel, A Sabt, M Korycka-Machala, RM Badi, NT Son, NX Ha, ... Bioorganic Chemistry 144, 107138, 2024 | 8 | 2024 |
| A high-fat diet rich in corn oil exaggerates the infarct size and memory impairment in rats with cerebral ischemia and is associated with suppressing osteopontin and Akt, and … DG Mostafa, HH Satti, EF Khaleel, RM Badi Journal of physiology and biochemistry 76, 393-406, 2020 | 8 | 2020 |
| Antiplatelet activity of astaxanthin in control- and high cholesterol-fed rats mediated by down-regulation of P2Y12, inhibition of NF-κB, and increasing intracellular … HH Satti, EF Khaleel, RM Badi, AO Elrefaie, DG Mostafa Platelets 32 (4), 469-478, 2021 | 7 | 2021 |
| Eriodictyol attenuates doxorubicin-induced nephropathy by activating the AMPK/Nrf2 signalling pathway RM Badi, EF Khaleel, HH Satti, R Monir Journal of Traditional and Complementary Medicine 14 (2), 203-214, 2024 | 5 | 2024 |
| Discovery of pyrimidine-tethered benzothiazole derivatives as novel anti-tubercular agents towards multi- and extensively drug resistant Mycobacterium tuberculosis LR Hemeda, MA El Hassab, MA Abdelgawad, EF Khaleel, MM Abdel-Aziz, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2250575, 2023 | 5 | 2023 |
| Mechanism of action of oxytocin as cardioprotection in rat model of myocardial infarction DG Mostafa, EF Khaleel, GA Abdel-Aleem IOSR J Dent Med Sci 14, 25-36, 2015 | 5 | 2015 |
| Gastroprotective effect of flavonoid quercetin and coenzyme Q10 in indomethacin-induced gastric ulcers in normal and diabetic rats EF Khaleel, DG Mostafa, GA Abdel-Aleem OSR J. Dent. Med. Sci 14 (12), 58-71, 2015 | 5 | 2015 |
