| Hybrid compounds as direct multitarget ligands: a review M Oliveira Pedrosa, RM Duarte da Cruz, J Oliveira Viana, RO de Moura, ... Current topics in medicinal chemistry 17 (9), 1044-1079, 2017 | 125 | 2017 |
| Synthesis, DNA binding, and antiproliferative activity of novel acridine-thiosemicarbazone derivatives SMV Almeida, EA Lafayette, LPB Gomes da Silva, CAC Amorim, ... International journal of molecular sciences 16 (6), 13023-13042, 2015 | 99 | 2015 |
| Thiosemicarbazones and 4-thiazolidinones indole-based derivatives: Synthesis, evaluation of antiproliferative activity, cell death mechanisms and topoisomerase inhibition assay JF de Oliveira, TS Lima, DB Vendramini-Costa, SCB de Lacerda Pedrosa, ... European journal of medicinal chemistry 136, 305-314, 2017 | 85 | 2017 |
| Synthesis of thiophene-thiosemicarbazone derivatives and evaluation of their in vitro and in vivo antitumor activities JF de Oliveira, AL da Silva, DB Vendramini-Costa, CA da Cruz Amorim, ... European journal of medicinal chemistry 104, 148-156, 2015 | 82 | 2015 |
| 2-Amino-thiophene derivatives present antileishmanial activity mediated by apoptosis and immunomodulation in vitro KA da Franca Rodrigues, CN de Sousa Dias, PL do Nascimento Néris, ... European journal of medicinal chemistry 106, 1-14, 2015 | 77 | 2015 |
| Thiophene-based compounds with potential anti-inflammatory activity RMD da Cruz, FJB Mendonça-Junior, NB de Mélo, L Scotti, ... Pharmaceuticals 14 (7), 692, 2021 | 76 | 2021 |
| Synthesis, Structure-Activity Relationships (SAR) and in Silico Studies of Coumarin Derivatives with Antifungal Activity RSA De Araújo, FQS Guerra, E de O. Lima, CA De Simone, JF Tavares, ... International journal of molecular sciences 14 (1), 1293-1309, 2013 | 68 | 2013 |
| Genetic mechanisms of antibiotic resistance and the role of antibiotic adjuvants DS Pontes, RSA de Araujo, N Dantas, L Scotti, MT Scotti, RO de Moura, ... Current topics in medicinal chemistry 18 (1), 42-74, 2018 | 61 | 2018 |
| Synthesis of novel indole derivatives as promising DNA-binding agents and evaluation of antitumor and antitopoisomerase I activities EA Lafayette, SMV de Almeida, RVC Santos, JF de Oliveira, ... European journal of medicinal chemistry 136, 511-522, 2017 | 59 | 2017 |
| Synthesis, DNA binding and topoisomerase I inhibition activity of thiazacridine and imidazacridine derivatives EA Lafayette, V de Almeida, S Mônica, MG Da Rocha Pitta, ... Molecules 18 (12), 15035-15050, 2013 | 56 | 2013 |
| Active essential oils and their components in use against neglected diseases and arboviruses EC Luna, IS Luna, L Scotti, AFM Monteiro, MT Scotti, RO de Moura, ... Oxidative medicine and cellular longevity 2019 (1), 6587150, 2019 | 54 | 2019 |
| Novel 4-quinoline-thiosemicarbazone derivatives: Synthesis, antiproliferative activity, in vitro and in silico biomacromolecule interaction studies and topoisomerase inhibition AG Ribeiro, SMV de Almeida, JF de Oliveira, TRC de Lima Souza, ... European Journal of Medicinal Chemistry 182, 111592, 2019 | 53 | 2019 |
| An electrochemical biosensor based on Hairpin-DNA modified gold electrode for detection of DNA damage by a hybrid cancer drug intercalation KL Untiveros, EG da Silva, FC de Abreu, EF da Silva-Júnior, ... Biosensors and Bioelectronics 133, 160-168, 2019 | 48 | 2019 |
| Toxicity and antitumor activity of a thiophene–acridine hybrid T Lisboa, D Silva, S Duarte, R Ferreira, C Andrade, AL Lopes, J Ribeiro, ... Molecules 25 (1), 64, 2019 | 46 | 2019 |
| New spiro-acridines: DNA interaction, antiproliferative activity and inhibition of human DNA topoisomerases SMV de Almeida, EA Lafayette, WL Silva, V de Lima Serafim, ... International journal of biological macromolecules 92, 467-475, 2016 | 45 | 2016 |
| Experimental methodologies and evaluations of computer-aided drug design methodologies applied to a series of 2-aminothiophene derivatives with antifungal activities L Scotti, M Tullius Scotti, E de Oliveira Lima, M Sobral da Silva, ... Molecules 17 (3), 2298-2315, 2012 | 45 | 2012 |
| Improvement of solubility and antifungal activity of a new aminothiophene derivative by complexation with 2-hydroxypropyl-β-cyclodextrin GRA Eleamen, SC Costa, RG Lima-Neto, RP Neves, LA Rolim, ... Journal of the Brazilian Chemical Society 28, 116-125, 2017 | 40 | 2017 |
| Novel indole-thiazole and indole-thiazolidinone derivatives as DNA groove binders JEF Alves, JF de Oliveira, TRC de Lima Souza, RO de Moura, ... International Journal of Biological Macromolecules 170, 622-635, 2021 | 38 | 2021 |
| Synthesis, DNA and protein interactions and human topoisomerase inhibition of novel Spiroacridine derivatives RG Gouveia, AG Ribeiro, MÂSP Segundo, JF de Oliveira, MCA de Lima, ... Bioorganic & Medicinal Chemistry 26 (22), 5911-5921, 2018 | 34 | 2018 |
| Synthesis and anticancer evaluation of thiazacridine derivatives reveals new selective molecules to hematopoietic neoplastic cells MJB de Melo Rego, WLB de Sena, RO de Moura, ITT Jacob, ... Combinatorial Chemistry & High Throughput Screening 20 (8), 713-718, 2017 | 34 | 2017 |
