| Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus Q Lu, M Kaplan, D Ray, D Ray, S Zacharek, D Gutsch, B Richardson Arthritis & Rheumatism 46 (5), 1282-1291, 2002 | 359 | 2002 |
| Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors M Yu, T Mazor, H Huang, HT Huang, KL Kathrein, AJ Woo, CR Chouinard, ... Molecular cell 45 (3), 330-343, 2012 | 254 | 2012 |
| Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion JS Dovey, SJ Zacharek, CF Kim, JA Lees Proceedings Of The National Academy Of Sciences 105 (33), 11857-11862, 2008 | 229 | 2008 |
| Durable anticancer immunity from intratumoral administration of IL-23, IL-36γ, and OX40L mRNAs SL Hewitt, A Bai, D Bailey, K Ichikawa, J Zielinski, R Karp, A Apte, ... Science translational medicine 11 (477), eaat9143, 2019 | 214 | 2019 |
| WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1–CUL4–ROC1 ligase J Hu, S Zacharek, YJ He, H Lee, S Shumway, RJ Duronio, Y Xiong Genes & development 22 (7), 866-871, 2008 | 171 | 2008 |
| Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci SJ Zacharek, CM Fillmore, AN Lau, DW Gludish, A Chou, JWK Ho, ... Cell stem cell 9 (3), 272-281, 2011 | 154 | 2011 |
| The combined effect of FGFR inhibition and PD-1 blockade promotes tumor-intrinsic induction of antitumor immunity S Palakurthi, M Kuraguchi, SJ Zacharek, E Zudaire, W Huang, DM Bonal, ... Cancer immunology research 7 (9), 1457-1471, 2019 | 123 | 2019 |
| Bacteria targeted by human natural antibodies using α-Gal conjugated receptor-specific glycopolymers J Li, S Zacharek, X Chen, J Wang, W Zhang, A Janczuk, PG Wang Bioorganic & medicinal chemistry 7 (8), 1549-1558, 1999 | 102 | 1999 |
| Enhanced inhibition of human anti-gal antibody binding to mammalian cells by synthetic α-gal epitope polymers JQ Wang, X Chen, W Zhang, S Zacharek, Y Chen, PG Wang Journal of the American Chemical Society 121 (36), 8174-8181, 1999 | 94 | 1999 |
| Negative regulation of TSC1-TSC2 by mammalian D-type cyclins SJ Zacharek, Y Xiong, SD Shumway Cancer research 65 (24), 11354-11360, 2005 | 85 | 2005 |
| A phase I study of mRNA-2752, a lipid nanoparticle encapsulating mRNAs encoding human OX40L, IL-23, and IL-36γ, for intratumoral (iTu) injection alone and in combination with … MR Patel, TM Bauer, A Jimeno, D Wang, P LoRusso, KT Do, SM Stemmer, ... Journal of Clinical Oncology 38 (15_suppl), 3092-3092, 2020 | 77* | 2020 |
| Duality of p27Kip1 function in tumorigenesis P Sicinski, S Zacharek, C Kim Genes & development 21 (14), 1703-1706, 2007 | 70 | 2007 |
| PLA2 promotes fusion between PMN-specific granules and complex liposomes RA Blackwood, AT Transue, DM Harsh, RC Brower, SJ Zacharek, ... Journal of Leucocyte Biology 59 (5), 663-670, 1996 | 34 | 1996 |
| Abstract CT032: A phase 1/2, open-label, multicenter, dose escalation and efficacy study of mRNA-2416, a lipid nanoparticle encapsulated mRNA encoding human OX40L, for … A Jimeno, S Gupta, R Sullivan, KT Do, WL Akerley, D Wang, D Teoh, ... Cancer Research 80 (16_Supplement), CT032-CT032, 2020 | 31 | 2020 |
| Spatial Mapping and Immunomodulatory Role of the OX40/OX40L Pathway in Human Non–Small Cell Lung Cancer A Porciuncula, M Morgado, R Gupta, K Syrigos, R Meehan, SJ Zacharek, ... Clinical Cancer Research 27 (22), 6174-6183, 2021 | 23 | 2021 |
| The combined effect of FGFR inhibition and PD-1 blockade promotes tumor-intrinsic induction of antitumor immunity. Cancer Immunol. Res. 2019; 7: 1457–1471. doi: 10.1158/2326-6066 S Palakurthi, M Kuraguchi, SJ Zacharek, E Zudaire, W Huang, DM Bonal, ... CIR-18-0595.[Abstract][CrossRef][Google Scholar], 2019 | 19 | 2019 |
| Cell Type–dependent Requirement for PIP Box–regulated Cdt1 Destruction During S Phase HO Lee, SJ Zacharek, Y Xiong, RJ Duronio Molecular biology of the cell 21 (21), 3639-3653, 2010 | 19 | 2010 |
| Stem cell biology in the lung and lung cancers: using pulmonary context and classic approaches DM Raiser, SJ Zacharek, RR Roach, SJ Curtis, KW Sinkevicius, ... Cold Spring Harbor Symposia on Quantitative Biology 73, 479-490, 2008 | 15 | 2008 |
| Abstract CT210: A Phase I, open-label, multicenter, dose escalation study of mRNA-2752, a lipid nanoparticle encapsulating mRNAs encoding human OX40L, IL-23, and IL-36γ, for … T Bauer, M Patel, A Jimeno, D Wang, J McDermott, S Zacharek, ... Cancer Research 79 (13_Supplement), CT210-CT210, 2019 | 14 | 2019 |
| 767 Safety and preliminary efficacy of mRNA-2752, a lipid nanoparticle encapsulating mRNAs encoding human OX40L/IL-23/IL-36γ for intratumoral (ITu) injection, and durvalumab … D Olson, A Daud, R Shapira-Frommer, A Jimeno, P Reagan, S Kummar, ... Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | 4 | 2022 |
