| Minimum information about a biosynthetic gene cluster MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ... Nature chemical biology 11 (9), 625-631, 2015 | 888 | 2015 |
| The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin. T Schwecke, JF Aparicio, I Molnar, A König, LE Khaw, SF Haydock, ... Proceedings of the National Academy of Sciences 92 (17), 7839-7843, 1995 | 620 | 1995 |
| Conserved amino acid residues correlating with ketoreductase stereospecificity in modular polyketide synthases P Caffrey ChemBioChem 4 (7), 654-657, 2003 | 415 | 2003 |
| Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes P Caffrey, S Lynch, E Flood, S Finnan, M Oliynyk Chemistry & biology 8 (7), 713-723, 2001 | 337 | 2001 |
| Stereospecific acyl transfers on the erythromycin-producing polyketide synthase AFA Marsden, P Caffrey, JF Aparicio, MS Loughran, J Staunton, ... Science 263 (5145), 378-380, 1994 | 215 | 1994 |
| Polyene antibiotic biosynthesis gene clusters JF Aparicio, P Caffrey, JA Gil, SB Zotchev Applied microbiology and biotechnology 61, 179-188, 2003 | 191 | 2003 |
| Identification of DEBS 1, DEBS 2 and DEBS 3, the multienzyme polypeptides of the erythromycin-producing polyketide synthase from Saccharopolyspora erythraea P Caffrey, DJ Bevitt, J Staunton, PF Leadlay FEBS letters 304 (2-3), 225-228, 1992 | 186 | 1992 |
| Evidence for a double-helical structure for modular polyketide synthases J Staunton, P Caffrey, JF Aparicio, GA Roberts, SS Bethell, PF Leadlay Nature structural biology 3 (2), 188-192, 1996 | 184 | 1996 |
| Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups M Carmody, B Murphy, B Byrne, P Power, D Rai, B Rawlings, P Caffrey Journal of Biological Chemistry 280 (41), 34420-34426, 2005 | 127 | 2005 |
| Limited proteolysis and active-site studies of the first multienzyme component of the erythromycin-producing polyketide synthase. JF Aparicio, P Caffrey, AF Marsden, J Staunton, PF Leadlay Journal of Biological Chemistry 269 (11), 8524-8528, 1994 | 116 | 1994 |
| Biosynthetic engineering of polyene macrolides towards generation of improved antifungal and antiparasitic agents P Caffrey, JF Aparicio, F Malpartida, SB Zotchev Current topics in medicinal chemistry 8 (8), 639-653, 2008 | 105 | 2008 |
| Biosynthesis of deoxyamphotericins and deoxyamphoteronolides by engineered strains of Streptomyces nodosus B Byrne, M Carmody, E Gibson, B Rawlings, P Caffrey Chemistry & biology 10 (12), 1215-1224, 2003 | 86 | 2003 |
| Analysis and manipulation of amphotericin biosynthetic genes by means of modified phage KC515 transduction techniques M Carmody, B Byrne, B Murphy, C Breen, S Lynch, E Flood, S Finnan, ... Gene 343 (1), 107-115, 2004 | 72 | 2004 |
| An acyl‐carrier‐protein – thioesterase domain from the 6‐deoxyerythronolide B synthase of Saccharopolyspora erythraea High‐level production, purification and … P Caffrey, B Green, LC Packman, BJ Rawlings, J Staunton, PF Leadlay European journal of biochemistry 195 (3), 823-830, 1991 | 69 | 1991 |
| Engineered synthesis of 7-oxo-and 15-deoxy-15-oxo-amphotericins: insights into structure-activity relationships in polyene antibiotics P Power, T Dunne, B Murphy, LN Lochlainn, D Rai, C Borissow, ... Chemistry & biology 15 (1), 78-86, 2008 | 58 | 2008 |
| Purification and N-terminal sequence of the alpha subunit of antigen 43, a unique protein complex associated with the outer membrane of Escherichia coli P Caffrey, P Owen Journal of bacteriology 171 (7), 3634-3640, 1989 | 56 | 1989 |
| The thioesterase of the erythromycin-producing polyketide synthase: mechanistic studies in vitro to investigate its mode of action and substrate specificity R Aggarwal, P Caffrey, PF Leadlay, CJ Smith, J Staunton Journal of the Chemical Society, Chemical Communications, 1519-1520, 1995 | 51 | 1995 |
| Identification and partial characterization of a novel bipartite protein antigen associated with the outer membrane of Escherichia coli P Owen, P Caffrey, LG Josefsson Journal of bacteriology 169 (8), 3770-3777, 1987 | 50 | 1987 |
| Polyene macrolide biosynthesis in streptomycetes and related bacteria: recent advances from genome sequencing and experimental studies P Caffrey, E De Poire, J Sheehan, P Sweeney Applied microbiology and biotechnology 100, 3893-3908, 2016 | 49 | 2016 |
| Redesign of polyene macrolide glycosylation: engineered biosynthesis of 19-(O)-perosaminyl-amphoteronolide B E Hutchinson, B Murphy, T Dunne, C Breen, B Rawlings, P Caffrey Chemistry & biology 17 (2), 174-182, 2010 | 49 | 2010 |
