Synthesis of chalcones derivatives and their biological activities: a review NAA Elkanzi, H Hrichi, RA Alolayan, W Derafa, FM Zahou, RB Bakr ACS omega 7 (32), 27769-27786, 2022 | 143 | 2022 |
Design, synthesis and biological evaluation of some novel benzothiazole/benzoxazole and/or benzimidazole derivatives incorporating a pyrazole scaffold as antiproliferative agents MA Abdelgawad, RB Bakr, HA Omar Bioorganic chemistry 74, 82-90, 2017 | 113 | 2017 |
Design, synthesis and antitumor activity of novel pyrazolo [3, 4-d] pyrimidine derivatives as EGFR-TK inhibitors MA Abdelgawad, RB Bakr, OA Alkhoja, WR Mohamed Bioorganic chemistry 66, 88-96, 2016 | 79 | 2016 |
Novel pyrimidine-pyridine hybrids: synthesis, cyclooxygenase inhibition, anti-inflammatory activity and ulcerogenic liability MA Abdelgawad, RB Bakr, AA Azouz Bioorganic Chemistry 77, 339-348, 2018 | 74 | 2018 |
Pyrimidine and fused pyrimidine derivatives as promising protein kinase inhibitors for cancer treatment KRA Abdellatif, RB Bakr Medicinal Chemistry Research 30, 31-49, 2021 | 59 | 2021 |
New pyrimidine-benzoxazole/benzimidazole hybrids: Synthesis, antioxidant, cytotoxic activity, in vitro cyclooxygenase and phospholipase A2-V inhibition MA Abdelgawad, RB Bakr, W Ahmad, MM Al-Sanea, HAH Elshemy Bioorganic chemistry 92, 103218, 2019 | 58 | 2019 |
New advances in synthesis and clinical aspects of pyrazolo [3, 4-d] pyrimidine scaffolds KRA Abdellatif, RB Bakr Bioorganic Chemistry 78, 341-357, 2018 | 56 | 2018 |
Synthesis and Anticancer Activity of Some New Pyrazolo[3,4-d]pyrimidin-4-one Derivatives KRA Abdellatif, EKA Abdelall, MA Abdelgawad, RR Ahmed, RB Bakr Molecules 19 (3), 3297-3309, 2014 | 52 | 2014 |
Synthesis, cyclooxygenase inhibition, anti-inflammatory evaluation and ulcerogenic liability of new 1-phenylpyrazolo[3,4-d]pyrimidine derivatives RB Bakr, AA Azouz, KRA Abdellatif Journal of enzyme inhibition and medicinal chemistry 31 (sup2), 6-12, 2016 | 47 | 2016 |
New 1, 2, 3-triazole-containing hybrids as antitumor candidates: Design, click reaction synthesis, DFT calculations, and molecular docking study IH El Azab, HS El-Sheshtawy, RB Bakr, NAA Elkanzi Molecules 26 (3), 708, 2021 | 38 | 2021 |
Nitric oxide-NASIDS donor prodrugs as hybrid safe anti-inflammatory agents K RA Abdellatif, E KA Abdelall, R B Bakr Current topics in medicinal chemistry 17 (8), 941-955, 2017 | 38 | 2017 |
Sulfonamide-based 4-anilinoquinoline derivatives as novel dual Aurora kinase (AURKA/B) inhibitors: Synthesis, biological evaluation and in silico insights MM Al-Sanea, A Elkamhawy, S Paik, K Lee, AM El Kerdawy, BSN Abbas, ... Bioorganic & medicinal chemistry 28 (13), 115525, 2020 | 32 | 2020 |
Selective cyclooxygenase inhibition and ulcerogenic liability of some newly prepared anti-inflammatory agents having thiazolo [4, 5-d] pyrimidine scaffold RB Bakr, AA Ghoneim, AA Azouz Bioorganic chemistry 88, 102964, 2019 | 32 | 2019 |
Synthesis, EGFR Inhibition and Anti-cancer Activity of New 3, 6-dimethyl-1-phenyl-4-(substituted-methoxy) pyrazolo [3, 4-d] pyrimidine Derivatives R B Bakr, A BM Mehany, K RA Abdellatif Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2017 | 31 | 2017 |
Novel phenolic compounds as potential dual EGFR and COX-2 inhibitors: Design, semisynthesis, in vitro biological evaluation and in silico Insights MA Abdelgawad, A Musa, AH Almalki, SI Alzarea, EM Mostafa, ... Drug design, development and therapy, 2325-2337, 2021 | 30 | 2021 |
Design, Synthesis, Molecular Modeling Study, and Antimicrobial Activity of Some Novel Pyrano [2, 3‐b] pyridine and Pyrrolo [2, 3‐b] pyrano [2.3‐d] pyridine Derivatives NAA Elkanzi, RB Bakr, AA Ghoneim Journal of Heterocyclic Chemistry, 2019 | 29 | 2019 |
Efficient and Recoverable Bio-Organic Catalyst Cysteine for Synthesis, Docking Study, and Antifungal Activity of New Bio-Active 3,4-Dihydropyrimidin-2(1H)-ones … NAA Elkanzi, AM Kadry, RM Ryad, RB Bakr, MAEAA Ali El-Remaily, ... ACS omega 7 (26), 22839-22849, 2022 | 26 | 2022 |
Preparation of some novel thiazolidinones, imidazolinones, and azetidinone bearing pyridine and pyrimidine moieties with antimicrobial activity RB Bakr, NAA Elkanzi Journal of heterocyclic chemistry 57 (7), 2977-2989, 2020 | 24 | 2020 |
Discovery of a COX-2 selective inhibitor hit with anti-inflammatory activity and gastric ulcer protective effect MA Abdelgawad, RB Bakr, AO El-Gendy, GM Kamel, AA Azouz, ... Future medicinal chemistry 9 (16), 1899-1912, 2017 | 24 | 2017 |
Design and synthesis of new EGFR-tyrosine kinase inhibitors containing pyrazolo [3, 4-d] pyrimidine cores as anticancer agents RB Bakr, EKA Abdelall, MK Abdel-Hamid, MM Kandeel Bulletin of Pharmaceutical Sciences Assiut University 35 (1), 27-42, 2012 | 24 | 2012 |