| Co-occurrence of DNMT3A, NPM1, FLT3 mutations identifies a subset of acute myeloid leukemia with adverse prognosis MF Bezerra, AS Lima, MR Piqué-Borràs, DR Silveira, JL Coelho-Silva, ... Blood, The Journal of the American Society of Hematology 135 (11), 870-875, 2020 | 70 | 2020 |
| Insulin Substrate Receptor (IRS) proteins in normal and malignant hematopoiesis JA Machado-Neto, BA Fenerich, APN Rodrigues Alves, JC Fernandes, ... Clinics 73 (suppl 1), e566s, 2018 | 44 | 2018 |
| High ΔNp73/TAp73 ratio is associated with poor prognosis in acute promyelocytic leukemia AR Lucena-Araujo, HT Kim, C Thomé, RH Jacomo, RA Melo, ... Blood, The Journal of the American Society of Hematology 126 (20), 2302-2306, 2015 | 42 | 2015 |
| IGF1R/IRS1 targeting has cytotoxic activity and inhibits PI3K/AKT/mTOR and MAPK signaling in acute lymphoblastic leukemia cells APNR Alves, JC Fernandes, BA Fenerich, JL Coelho-Silva, PS Scheucher, ... Cancer Letters 456, 59-68, 2019 | 33 | 2019 |
| NT157 has antineoplastic effects and inhibits IRS1/2 and STAT3/5 in JAK2V617F-positive myeloproliferative neoplasm cells BA Fenerich, JC Fernandes, APN Rodrigues Alves, JL Coelho-Silva, ... Signal transduction and targeted therapy 5 (1), 5, 2020 | 32 | 2020 |
| Combining gene mutation with gene expression analysis improves outcome prediction in acute promyelocytic leukemia AR Lucena-Araujo, JL Coelho-Silva, DA Pereira-Martins, DR Silveira, ... Blood, The Journal of the American Society of Hematology 134 (12), 951-959, 2019 | 30 | 2019 |
| Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms JA Machado-Neto, BA Fenerich, R Scopim-Ribeiro, CA Eide, ... Cell death & disease 9 (3), 311, 2018 | 27 | 2018 |
| Wettability of edible coatings on Nile tilapia fillets (Oreochromis niloticus) LO Alcântara, ME de Oliveira Martins, JR Sousa, MÂ Cerqueira, ... Journal of Food Engineering 247, 152-159, 2019 | 23 | 2019 |
| PIP4K2A and PIP4K2C transcript levels are associated with cytogenetic risk and survival outcomes in acute myeloid leukemia K Lima, JL Coelho-Silva, GS Kinker, DA Pereira-Martins, F Traina, ... Cancer Genetics 233, 56-66, 2019 | 21 | 2019 |
| Integrating clinical features with genetic factors enhances survival prediction for adults with acute myeloid leukemia DRA Silveira, L Quek, IS Santos, A Corby, JL Coelho-Silva, ... Blood advances 4 (10), 2339-2350, 2020 | 18 | 2020 |
| Comprehensive analysis of cytoskeleton regulatory genes identifies ezrin as a prognostic marker and molecular target in acute myeloid leukemia JC Lipreri da Silva, JL Coelho-Silva, K Lima, HP Vicari, M Lazarini, ... Cellular Oncology 44 (5), 1105-1117, 2021 | 17 | 2021 |
| Autophagy inhibition potentiates ruxolitinib-induced apoptosis in JAK2V617F cells JA Machado-Neto, JL Coelho-Silva, FPS Santos, PS Scheucher, ... Investigational New Drugs 38, 733-745, 2020 | 17 | 2020 |
| Clinical impact of BAALC expression in high-risk acute promyelocytic leukemia AR Lucena-Araujo, DA Pereira-Martins, LC Koury, PL Franca-Neto, ... Blood advances 1 (21), 1807-1814, 2017 | 14 | 2017 |
| Paclitaxel induces Stathmin 1 phosphorylation, microtubule stability and apoptosis in acute lymphoblastic leukemia cells JA Machado-Neto, APNR Alves, JC Fernandes, JL Coelho-Silva, ... Heliyon 3 (9), 2017 | 14 | 2017 |
| The PIP4K2 inhibitor THZ-P1-2 exhibits antileukemia activity by disruption of mitochondrial homeostasis and autophagy K Lima, DA Pereira-Martins, LBL de Miranda, JL Coelho-Silva, ... Blood cancer journal 12 (11), 151, 2022 | 12 | 2022 |
| NT157, an IGF1R-IRS1/2 inhibitor, exhibits antineoplastic effects in pre-clinical models of chronic myeloid leukemia R Scopim-Ribeiro, JA Machado-Neto, CA Eide, JL Coelho-Silva, ... Investigational New Drugs 39, 736-746, 2021 | 11 | 2021 |
| Prognostic importance of CD56 expression in intermediate risk acute myeloid leukaemia. JL Coelho‐Silva, LE Carvalho, MM Oliveira, PL Franca‐Neto, AT Andrade, ... British journal of haematology 176 (3), 2017 | 11 | 2017 |
| A multicenter comparative acute myeloid leukemia study: can we explain the differences in the outcomes in resource-constrained settings? DRA Silveira, JL Coelho-Silva, WF Silva, G Vallance, DA Pereira-Martins, ... Leukemia & Lymphoma 62 (1), 147-157, 2021 | 10 | 2021 |
| MLL5 improves ATRA driven differentiation and promotes xenotransplant engraftment in acute promyelocytic leukemia model DA Pereira-Martins, I Weinhäuser, JL Coelho-Silva, PL França-Neto, ... Cell death & disease 12 (4), 371, 2021 | 9 | 2021 |
| Association between the TP53 Arg72Pro polymorphism and clinical outcomes in acute myeloid leukemia MF Bezerra, JL Coelho-Silva, JC Nascimento, MT Benicio, CR Rocha, ... haematologica 102 (2), e43, 2017 | 8 | 2017 |
João Agostinho Machado-NetoDepartment of Pharmacology, Institute of Biomedical Sciences of the University of São Paulo, Brazil在 usp.br 的电子邮件经过验证
João Agostinho Machado-NetoDepartment of Pharmacology, Institute of Biomedical Sciences of the University of São Paulo, Brazil在 usp.br 的电子邮件经过验证