hERG K+ channels: structure, function, and clinical significance JI Vandenberg, MD Perry, MJ Perrin, SA Mann, Y Ke, AP Hill Physiological reviews, 2012 | 759 | 2012 |
Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a GA Papadatos, PMR Wallerstein, CEG Head, R Ratcliff, PA Brady, ... Proceedings of the National Academy of Sciences 99 (9), 6210-6215, 2002 | 449 | 2002 |
HERG K+ channels: friend and foe JI Vandenberg, BD Walker, TJ Campbell Trends in Pharmacological Sciences 22 (5), 240-246, 2001 | 348 | 2001 |
A new perspective in the field of cardiac safety testing through the comprehensive in vitro proarrhythmia assay paradigm B Fermini, JC Hancox, N Abi-Gerges, M Bridgland-Taylor, KW Chaudhary, ... Journal of biomolecular screening 21 (1), 1-11, 2016 | 299 | 2016 |
Mechanisms of pHi recovery after global ischemia in the perfused heart. JI Vandenberg, JC Metcalfe, AA Grace Circulation research 72 (5), 993-1003, 1993 | 200 | 1993 |
Stretch-Sensitive KCNQ1Mutation: A Link Between Genetic and Environmental Factors in the Pathogenesis of Atrial Fibrillation? R Otway, JI Vandenberg, G Guo, A Varghese, ML Castro, J Liu, JT Zhao, ... Journal of the American College of Cardiology 49 (5), 578-586, 2007 | 177 | 2007 |
Domain reorientation and rotation of an intracellular assembly regulate conduction in Kir potassium channels OB Clarke, AT Caputo, AP Hill, JI Vandenberg, BJ Smith, JM Gulbis Cell 141 (6), 1018-1029, 2010 | 168 | 2010 |
Swelling-activated and isoprenaline-activated chloride currents in guinea pig cardiac myocytes have distinct electrophysiology and pharmacology. JI Vandenberg, A Yoshida, K Kirk, T Powell The Journal of general physiology 104 (6), 997-1017, 1994 | 162 | 1994 |
The sodium channel β-subunit SCN3b modulates the kinetics of SCN5a and is expressed heterogeneously in sheep heart AI Fahmi, M Patel, EB Stevens, AL Fowden, JE John III, K Lee, R Pinnock, ... The Journal of physiology 537 (Pt 3), 693, 2001 | 154 | 2001 |
Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene Scn5a M Lei, C Goddard, J Liu, AL Léoni, A Royer, SSM Fung, G Xiao, A Ma, ... The Journal of physiology 567 (2), 387-400, 2005 | 151 | 2005 |
Cell swelling and ion transport pathways in cardiac myocytes JI Vandenberg, SA Rees, AR Wright, T Powell Cardiovascular research 32 (1), 85-97, 1996 | 151 | 1996 |
Drug binding to the inactivated state is necessary but not sufficient for high-affinity binding to human ether-a-go-go-related gene channels MJ Perrin, PW Kuchel, TJ Campbell, JI Vandenberg Molecular Pharmacology 74 (5), 1443-1452, 2008 | 147 | 2008 |
Human ether-a-go-go related gene (hERG) K+ channels: function and dysfunction MJ Perrin, RN Subbiah, JI Vandenberg, AP Hill Progress in biophysics and molecular biology 98 (2-3), 137-148, 2008 | 147 | 2008 |
Effects of premature stimulation on HERG K+ channels YL Martyn, P Mahaut‐Smith, A Varghese, CLH Huang, PR Kemp, ... The Journal of physiology 537 (3), 843-851, 2001 | 147 | 2001 |
R222Q SCN5A Mutation Is Associated With Reversible Ventricular Ectopy and Dilated Cardiomyopathy SA Mann, ML Castro, M Ohanian, G Guo, P Zodgekar, A Sheu, ... Journal of the American College of Cardiology 60 (16), 1566-1573, 2012 | 143 | 2012 |
Temperature dependence of human ether-à-go-go-related gene K+ currents JI Vandenberg, A Varghese, Y Lu, JA Bursill, MP Mahaut-Smith, ... American Journal of Physiology-Cell Physiology 291 (1), C165-C175, 2006 | 137 | 2006 |
A universal and robust integrated platform for the scalable production of human cardiomyocytes from pluripotent stem cells H Fonoudi, H Ansari, S Abbasalizadeh, MR Larijani, S Kiani, ... Stem cells translational medicine 4 (12), 1482-1494, 2015 | 123 | 2015 |
Lentiviral vectors for delivery of genes into neonatal and adult ventricular cardiac myocytes in vitro and in vivo J Zhao, GJ Pettigrew, J Thomas, JI Vandenberg, L Delriviere, EM Bolton, ... Basic research in cardiology 97, 348-358, 2002 | 122 | 2002 |
Potassium channels in the heart: structure, function and regulation E Grandi, MC Sanguinetti, DC Bartos, DM Bers, Y Chen‐Izu, ... The Journal of physiology 595 (7), 2209-2228, 2017 | 109 | 2017 |
The N–terminal tail of hERG contains an amphipathic α–helix that regulates channel deactivation CA Ng, MJ Hunter, MD Perry, M Mobli, Y Ke, PW Kuchel, GF King, D Stock, ... PloS one 6 (1), e16191, 2011 | 108 | 2011 |