Trimethylamine-N-oxide promotes age-related vascular oxidative stress and endothelial dysfunction in mice and healthy humans VE Brunt, RA Gioscia-Ryan, AG Casso, NS VanDongen, BP Ziemba, ... Hypertension 76 (1), 101-112, 2020 | 205 | 2020 |
Short-term time-restricted feeding is safe and feasible in non-obese healthy midlife and older adults CR Martens, MJ Rossman, MR Mazzo, LR Jankowski, EE Nagy, ... Geroscience 42, 667-686, 2020 | 155 | 2020 |
Time‐efficient inspiratory muscle strength training lowers blood pressure and improves endothelial function, NO bioavailability, and oxidative stress in midlife/older adults … DH Craighead, TC Heinbockel, KA Freeberg, MJ Rossman, RA Jackman, ... Journal of the American Heart Association 10 (13), e020980, 2021 | 86 | 2021 |
Lateral diffusion of peripheral membrane proteins on supported lipid bilayers is controlled by the additive frictional drags of (1) bound lipids and (2) protein domains … BP Ziemba, JJ Falke Chemistry and physics of lipids 172, 67-77, 2013 | 86 | 2013 |
Regulation of PI3K by PKC and MARCKS: single-molecule analysis of a reconstituted signaling pathway BP Ziemba, JE Burke, G Masson, RL Williams, JJ Falke Biophysical journal 110 (8), 1811-1825, 2016 | 84 | 2016 |
Single-molecule study reveals how receptor and ras synergistically activate PI3Kα and PIP3 signaling TC Buckles, BP Ziemba, GR Masson, RL Williams, JJ Falke Biophysical Journal 113 (11), 2396-2405, 2017 | 72 | 2017 |
Gut microbiome-derived metabolite trimethylamine N-oxide induces aortic stiffening and increases systolic blood pressure with aging in mice and humans VE Brunt, AG Casso, RA Gioscia-Ryan, ZJ Sapinsley, BP Ziemba, ... Hypertension 78 (2), 499-511, 2021 | 70 | 2021 |
Lifelong voluntary aerobic exercise prevents age‐and Western diet‐induced vascular dysfunction, mitochondrial oxidative stress and inflammation in mice RA Gioscia‐Ryan, ZS Clayton, MC Zigler, JJ Richey, LM Cuevas, ... The Journal of physiology 599 (3), 911-925, 2021 | 60 | 2021 |
Single-molecule studies reveal a hidden key step in the activation mechanism of membrane-bound protein kinase C-α BP Ziemba, J Li, KE Landgraf, JD Knight, GA Voth, JJ Falke Biochemistry 53 (10), 1697-1713, 2014 | 57 | 2014 |
Apigenin restores endothelial function by ameliorating oxidative stress, reverses aortic stiffening, and mitigates vascular inflammation with aging ZS Clayton, DA Hutton, VE Brunt, NS VanDongen, BP Ziemba, AG Casso, ... American Journal of Physiology-Heart and Circulatory Physiology 321 (1 …, 2021 | 53 | 2021 |
Doxorubicin-induced oxidative stress and endothelial dysfunction in conduit arteries is prevented by mitochondrial-specific antioxidant treatment ZS Clayton, VE Brunt, DA Hutton, NS VanDongen, A D’Alessandro, ... Cardio Oncology 2 (3), 475-488, 2020 | 51 | 2020 |
A novel mechanism of ligand binding and release in the odorant binding protein 20 from the malaria mosquito Anopheles gambiae BP Ziemba, EJ Murphy, HT Edlin, DNM Jones Protein Science 22 (1), 11-21, 2013 | 46 | 2013 |
Short‐term interleukin‐37 treatment improves vascular endothelial function, endurance exercise capacity, and whole‐body glucose metabolism in old mice DB Ballak, VE Brunt, ZJ Sapinsley, BP Ziemba, JJ Richey, MC Zigler, ... Aging cell 19 (1), e13074, 2020 | 45 | 2020 |
The PH domain of phosphoinositide-dependent kinase-1 exhibits a novel, phospho-regulated monomer–dimer equilibrium with important implications for kinase domain activation … BP Ziemba, C Pilling, V Calleja, B Larijani, JJ Falke Biochemistry 52 (28), 4820-4829, 2013 | 41 | 2013 |
Assembly of membrane-bound protein complexes: detection and analysis by single molecule diffusion BP Ziemba, JD Knight, JJ Falke Biochemistry 51 (8), 1638-1647, 2012 | 41 | 2012 |
A PKC-MARCKS-PI3K regulatory module links Ca2+ and PIP3 signals at the leading edge of polarized macrophages BP Ziemba, JJ Falke PLoS One 13 (5), e0196678, 2018 | 39 | 2018 |
Interactions of protein kinase C-α C1A and C1B domains with membranes: a combined computational and experimental study J Li, BP Ziemba, JJ Falke, GA Voth Journal of the American Chemical Society 136 (33), 11757-11766, 2014 | 39 | 2014 |
Interplay between phosphoinositide lipids and calcium signals at the leading edge of chemotaxing ameboid cells JJ Falke, BP Ziemba Chemistry and physics of lipids 182, 73-79, 2014 | 35 | 2014 |
Inorganic nitrite supplementation improves endothelial function with aging: translational evidence for suppression of mitochondria-derived oxidative stress MJ Rossman, RA Gioscia-Ryan, JR Santos-Parker, BP Ziemba, ... Hypertension 77 (4), 1212-1222, 2021 | 33 | 2021 |
Tumor necrosis factor alpha-mediated inflammation and remodeling of the extracellular matrix underlies aortic stiffening induced by the common chemotherapeutic agent doxorubicin ZS Clayton, VE Brunt, DA Hutton, AG Casso, BP Ziemba, S Melov, ... Hypertension 77 (5), 1581-1590, 2021 | 32 | 2021 |