关注
Edward Manser
Edward Manser
Senior Principal Investigator, IMCB
在 imb.a-star.edu.sg 的电子邮件经过验证
标题
引用次数
引用次数
年份
A brain serine/threonine protein kinase activated by Cdc42 and Rac1
E Manser, T Leung, H Salihuddin, Z Zhao, L Lim
Nature 367 (6458), 40-46, 1994
19231994
The p160 RhoA-binding kinase ROKα is a member of a kinase family and is involved in the reorganization of the cytoskeleton
T Leung, XQ Chen, E Manser, L Lim
Molecular and cellular biology, 1996
11621996
A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes
T Leung, E Manser, L Tan, L Lim
Journal of Biological Chemistry 270 (49), 29051-29054, 1995
10221995
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
E Manser, TH Loo, CG Koh, ZS Zhao, XQ Chen, L Tan, I Tan, T Leung, ...
Molecular cell 1 (2), 183-192, 1998
9531998
Expression of constitutively active α-PAK reveals effects of the kinase on actin and focal complexes
E Manser, HY Huang, TH Loo, XQ Chen, JM Dong, T Leung, L Lim
Molecular and cellular biology, 1997
7521997
Rho GTPases and their role in organizing the actin cytoskeleton
ST Sit, E Manser
Journal of cell science 124 (5), 679-683, 2011
6202011
Ste20-like protein kinases are required for normal localization of cell growth and for cytokinesis in budding yeast.
F Cvrckova, C De Virgilio, E Manser, JR Pringle, K Nasmyth
Genes & development 9 (15), 1817-1830, 1995
5031995
Coupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassembly
Z Zhao, E Manser, TH Loo, L Lim
Molecular and cellular biology, 2000
4892000
A conserved negative regulatory region in αPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1
ZS Zhao, E Manser, XQ Chen, C Chong, T Leung, L Lim
Molecular and cellular biology, 1998
4091998
A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42
E Manser, T Leung, H Salihuddin, L Tan, L Lim
Nature 363 (6427), 364-367, 1993
4091993
Regulation of phosphorylation pathways by p21 GTPases: The p21 Ras‐related Rho subfamily and its role in phosphorylation signalling pathways
L Lim, E Manser, T Leung, C Hall
European Journal of Biochemistry 242 (2), 171-185, 1996
4041996
PRL-3 and PRL-1 promote cell migration, invasion, and metastasis
Q Zeng, JM Dong, K Guo, J Li, HX Tan, V Koh, CJ Pallen, E Manser, ...
Cancer research 63 (11), 2716-2722, 2003
3942003
Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization
T Leung, XQ Chen, I Tan, E Manser, L Lim
Molecular and cellular biology, 1998
3591998
PAK and other Rho-associated kinases–effectors with surprisingly diverse mechanisms of regulation
Z Zhao, E Manser
Biochemical Journal 386 (2), 201-214, 2005
3572005
cAMP-induced morphological changes are counteracted by the activated RhoA small GTPase and the Rho kinase ROKα
JM Dong, T Leung, E Manser, L Lim
Journal of Biological Chemistry 273 (35), 22554-22562, 1998
3351998
Molecular Cloning of a New Member of the p21-Cdc42/Rac-activated Kinase (PAK) Family (∗)
E Manser, C Chong, ZS Zhao, T Leung, G Michael, C Hall, L Lim
Journal of Biological Chemistry 270 (42), 25070-25078, 1995
3271995
PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition
H Wang, SY Quah, JM Dong, E Manser, JP Tang, Q Zeng
Cancer research 67 (7), 2922-2926, 2007
3222007
The mechanism of PAK activation: autophosphorylation events in both regulatory and kinase domains control activity
C Chong, L Tan, L Lim, E Manser
Journal of Biological Chemistry 276 (20), 17347-17353, 2001
3132001
The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A
Z Zhao, JP Lim, YW Ng, L Lim, E Manser
Molecular cell 20 (2), 237-249, 2005
2922005
A Drosophila Homolog of the Rac- and Cdc42-Activated Serine/Threonine Kinase PAK Is a Potential Focal Adhesion and Focal Complex Protein That Colocalizes …
N Harden, J Lee, HY Loh, YM Ong, I Tan, T Leung, E Manser, L Lim
Molecular and cellular biology 16 (5), 1896-1908, 1996
2711996
系统目前无法执行此操作,请稍后再试。
文章 1–20