| Nox2 complex–derived ROS as immune regulators O Sareila, T Kelkka, A Pizzolla, M Hultqvist, R Holmdahl Antioxidants & redox signaling 15 (8), 2197-2208, 2011 | 232 | 2011 |
| Mannan induces ROS-regulated, IL-17A–dependent psoriasis arthritis-like disease in mice I Khmaladze, T Kelkka, S Guerard, K Wing, A Pizzolla, A Saxena, ... Proceedings of the National Academy of Sciences 111 (35), E3669-E3678, 2014 | 142 | 2014 |
| Reactive oxygen species produced by the NADPH oxidase 2 complex in monocytes protect mice from bacterial infections A Pizzolla, M Hultqvist, B Nilson, MJ Grimm, T Eneljung, IM Jonsson, ... The Journal of Immunology 188 (10), 5003-5011, 2012 | 131 | 2012 |
| Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target O Dufva, M Kankainen, T Kelkka, N Sekiguchi, SA Awad, S Eldfors, ... Nature communications 9 (1), 1567, 2018 | 130 | 2018 |
| Reactive oxygen species deficiency induces autoimmunity with type 1 interferon signature T Kelkka, D Kienhöfer, M Hoffmann, M Linja, K Wing, O Sareila, ... Antioxidants & redox signaling 21 (16), 2231-2245, 2014 | 128 | 2014 |
| Somatic mutations in clonally expanded cytotoxic T lymphocytes in patients with newly diagnosed rheumatoid arthritis P Savola, T Kelkka, HL Rajala, A Kuuliala, K Kuuliala, S Eldfors, ... Nature communications 8 (1), 15869, 2017 | 110 | 2017 |
| Clever-1/stabilin-1 controls cancer growth and metastasis M Karikoski, F Marttila-Ichihara, K Elima, P Rantakari, M Hollmén, ... Clinical cancer research 20 (24), 6452-6464, 2014 | 100 | 2014 |
| Monocyte-and macrophage-targeted NADPH oxidase mediates antifungal host defense and regulation of acute inflammation in mice MJ Grimm, RR Vethanayagam, NG Almyroudis, CG Dennis, ANH Khan, ... The Journal of Immunology 190 (8), 4175-4184, 2013 | 89 | 2013 |
| Clonal hematopoiesis in patients with rheumatoid arthritis P Savola, S Lundgren, MAI Keränen, H Almusa, P Ellonen, ... Blood cancer journal 8 (8), 69, 2018 | 82 | 2018 |
| Hyperinflammation of chronic granulomatous disease is abolished by NOX2 reconstitution in macrophages and dendritic cells C Deffert, S Carnesecchi, H Yuan, AL Rougemont, T Kelkka, R Holmdahl, ... The Journal of pathology 228 (3), 341-350, 2012 | 74 | 2012 |
| Somatic STAT3 mutations in Felty syndrome: an implication for a common pathogenesis with large granular lymphocyte leukemia P Savola, O Brück, T Olson, T Kelkka, MJ Kauppi, PE Kovanen, S Kytölä, ... haematologica 103 (2), 304, 2018 | 71 | 2018 |
| Hydrogen peroxide as an immunological transmitter regulating autoreactive T cells R Holmdahl, O Sareila, A Pizzolla, S Winter, C Hagert, N Jaakkola, ... Antioxidants & redox signaling 18 (12), 1463-1474, 2013 | 62 | 2013 |
| Identification of a region in p47phox/NCF1 crucial for phagocytic NADPH oxidase (NOX2) activation O Sareila, N Jaakkola, P Olofsson, T Kelkka, R Holmdahl Journal of leukocyte biology 93 (3), 427-435, 2013 | 62 | 2013 |
| Sex bias in MHC I-associated shaping of the adaptive immune system T Schneider-Hohendorf, D Görlich, P Savola, T Kelkka, S Mustjoki, ... Proceedings of the National Academy of Sciences 115 (9), 2168-2173, 2018 | 50 | 2018 |
| The macrophage mannose receptor regulate mannan-induced psoriasis, psoriatic arthritis, and rheumatoid arthritis-like disease models C Hagert, O Sareila, T Kelkka, S Jalkanen, R Holmdahl Frontiers in immunology 9, 328004, 2018 | 45 | 2018 |
| Enhancement of antibody-induced arthritis via Toll-like receptor 2 stimulation is regulated by granulocyte reactive oxygen species T Kelkka, M Hultqvist, KS Nandakumar, R Holmdahl The American journal of pathology 181 (1), 141-150, 2012 | 42 | 2012 |
| Bacillus calmette-guerin infection in NADPH oxidase deficiency: defective mycobacterial sequestration and granuloma formation C Deffert, MG Schäppi, JC Pache, J Cachat, D Vesin, R Bisig, ... PLoS pathogens 10 (9), e1004325, 2014 | 38 | 2014 |
| Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors T Kelkka, A Pizzolla, JP Laurila, T Friman, R Gustafsson, E Källberg, ... PLoS One 8 (12), e84148, 2013 | 34 | 2013 |
| Single-cell characterization of leukemic and non-leukemic immune repertoires in CD8+ T-cell large granular lymphocytic leukemia J Huuhtanen, D Bhattacharya, T Lönnberg, M Kankainen, C Kerr, ... Nature Communications 13 (1), 1981, 2022 | 31 | 2022 |
| Identification of novel STAT5B mutations and characterization of TCRβ signatures in CD4+ T-cell large granular lymphocyte leukemia D Bhattacharya, A Teramo, VR Gasparini, J Huuhtanen, D Kim, ... Blood cancer journal 12 (2), 31, 2022 | 24 | 2022 |
