Drug resistance and treatment failure in leishmaniasis: A 21st century challenge A Ponte-Sucre, F Gamarro, JC Dujardin, MP Barrett, R López-Vélez, ... PLoS neglected tropical diseases 11 (12), e0006052, 2017 | 788 | 2017 |
Leishmania spp.: proficiency of drug-resistant parasites S Natera, C Machuca, M Padrón-Nieves, A Romero, E Díaz, ... International journal of antimicrobial agents 29 (6), 637-642, 2007 | 155 | 2007 |
Activities of Naphthylisoquinoline Alkaloids and Synthetic Analogs against Leishmania major A Ponte-Sucre, JH Faber, T Gulder, I Kajahn, SEH Pedersen, ... Antimicrobial agents and chemotherapy 51 (1), 188-194, 2007 | 117 | 2007 |
Ancistrocladinium A and B, the First N,C-Coupled Naphthyldihydroisoquinoline Alkaloids, from a Congolese Ancistrocladus Species G Bringmann, I Kajahn, M Reichert, SEH Pedersen, JH Faber, T Gulder, ... The Journal of Organic Chemistry 71 (25), 9348-9356, 2006 | 111 | 2006 |
Aziridine-2, 3-dicarboxylate inhibitors targeting the major cysteine protease of Trypanosoma brucei as lead trypanocidal agents R Vicik, V Hoerr, M Glaser, M Schultheis, E Hansell, JH McKerrow, ... Bioorganic & medicinal chemistry letters 16 (10), 2753-2757, 2006 | 110 | 2006 |
An Overview of Trypanosoma brucei Infections: An Intense Host–Parasite Interaction A Ponte-Sucre Frontiers in microbiology 7, 2126, 2016 | 96 | 2016 |
Aziridine-2, 3-dicarboxylates, peptidomimetic cysteine protease inhibitors with antileishmanial activity A Ponte-Sucre, R Vicik, M Schultheis, T Schirmeister, H Moll Antimicrobial agents and chemotherapy 50 (7), 2439-2447, 2006 | 94 | 2006 |
Treatment failure in leishmaniasis: drug-resistance or another (epi-) phenotype? M Vanaerschot, F Dumetz, S Roy, A Ponte-Sucre, J Arevalo, JC Dujardin Expert review of anti-infective therapy 12 (8), 937-946, 2014 | 89 | 2014 |
Physiological consequences of drug resistance in Leishmaniaand their relevance for chemotherapy A Ponte-Sucre Kinetoplastid Biology and Disease 2, 1-10, 2003 | 83 | 2003 |
Leishmania major lipophosphoglycan modulates the phenotype and inhibits migration of murine Langerhans cells A Ponte‐Sucre, D Heise, H Moll Immunology 104 (4), 462-467, 2001 | 69 | 2001 |
Availability and applications of ATP-binding cassette (ABC) transporter blockers A Ponte-Sucre Applied microbiology and biotechnology 76 (2), 279-286, 2007 | 63 | 2007 |
Structure−Activity Relationship and Studies on the Molecular Mechanism of Leishmanicidal N,C-Coupled Arylisoquinolinium Salts A Ponte-Sucre, T Gulder, A Wegehaupt, C Albert, C Rikanovic, ... Journal of medicinal chemistry 52 (3), 626-636, 2009 | 61 | 2009 |
Drug resistance in Leishmania parasites A Ponte-Sucre, E Diaz, M Padrón-Nieves Cham: Springer, 2013 | 46 | 2013 |
Antitrypanosomal activity of quaternary naphthalimide derivatives M Muth, V Hoerr, M Glaser, A Ponte-Sucre, H Moll, A Stich, U Holzgrabe Bioorganic & medicinal chemistry letters 17 (6), 1590-1593, 2007 | 46 | 2007 |
Do we need new drugs against human African trypanosomiasis? A Stich, A Ponte-Sucre, U Holzgrabe The Lancet Infectious Diseases 13 (9), 733-734, 2013 | 45 | 2013 |
Leishmania sp.: growth and survival are impaired by ion channel blockers A Ponte-Sucre, Y Campos, M Fernandez, H Moll, A Mendoza-León Experimental Parasitology 88 (1), 11-19, 1998 | 44 | 1998 |
Bis-acridines as lead antiparasitic agents: structure-activity analysis of a discrete compound library in vitro CR Caffrey, D Steverding, RK Swenerton, B Kelly, D Walshe, A Debnath, ... Antimicrobial agents and chemotherapy 51 (6), 2164-2172, 2007 | 40 | 2007 |
Novel lead compounds in pre-clinical development against African sleeping sickness M Berninger, I Schmidt, A Ponte-Sucre, U Holzgrabe MedChemComm 8 (10), 1872-1890, 2017 | 39 | 2017 |
ABC transporters in microorganisms: research, innovation and value as targets against drug resistance A Ponte-Sucre Caister Academic, 2009 | 34 | 2009 |
In search of novel agents for therapy of tropical diseases and human immunodeficiency virus T Goebel, D Ulmer, H Projahn, J Kloeckner, E Heller, M Glaser, ... Journal of medicinal chemistry 51 (2), 238-250, 2008 | 34 | 2008 |