Mechanism by which orally administered β-1, 3-glucans enhance the tumoricidal activity of antitumor monoclonal antibodies in murine tumor models F Hong, J Yan, JT Baran, DJ Allendorf, RD Hansen, GR Ostroff, PX Xing, ... The Journal of Immunology 173 (2), 797-806, 2004 | 643 | 2004 |
Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation M Aouadi, GJ Tesz, SM Nicoloro, M Wang, M Chouinard, E Soto, ... Nature 458 (7242), 1180-1184, 2009 | 619 | 2009 |
Effect of β-glucan from oats and yeast on serum lipids S Bell, VM Goldman, BR Bistrian, AH Arnold, G Ostroff, RA Forse Critical reviews in food science and nutrition 39 (2), 189-202, 1999 | 299 | 1999 |
β-Glucan functions as an adjuvant for monoclonal antibody immunotherapy by recruiting tumoricidal granulocytes as killer cells F Hong, RD Hansen, J Yan, DJ Allendorf, JT Baran, GR Ostroff, GD Ross Cancer research 63 (24), 9023-9031, 2003 | 248 | 2003 |
Drug delivery product and methods GR Ostroff US Patent 7,740,861, 2010 | 215 | 2010 |
Characterization of multilayered nanoparticles encapsulated in yeast cell wall particles for DNA delivery ER Soto, GR Ostroff Bioconjugate chemistry 19 (4), 840-848, 2008 | 198 | 2008 |
Glucan drug delivery system and adjuvant S Jamas, GR Ostroff, DD Easson Jr US Patent 5,607,677, 1997 | 198 | 1997 |
Distinct patterns of dendritic cell cytokine release stimulated by fungal β-glucans and toll-like receptor agonists H Huang, GR Ostroff, CK Lee, JP Wang, CA Specht, SM Levitz Infection and immunity 77 (5), 1774-1781, 2009 | 192 | 2009 |
Robust stimulation of humoral and cellular immune responses following vaccination with antigen-loaded β-glucan particles H Huang, GR Ostroff, CK Lee, CA Specht, SM Levitz MBio 1 (3), 10.1128/mbio. 00164-10, 2010 | 183 | 2010 |
HTT-lowering reverses Huntington’s disease immune dysfunction caused by NFκB pathway dysregulation U Träger, R Andre, N Lahiri, A Magnusson-Lind, A Weiss, S Grueninger, ... Brain 137 (3), 819-833, 2014 | 181 | 2014 |
Glucan drug delivery system and adjuvant S Jamas, GR Ostroff, DD Easson Jr US Patent 5,032,401, 1991 | 180 | 1991 |
Anti-infective effect of poly-beta 1-6-glucotriosyl-beta 1-3-glucopyranose glucan in vivo AB Onderdonk, RL Cisneros, P Hinkson, G Ostroff Infection and immunity 60 (4), 1642-1647, 1992 | 167 | 1992 |
β-Glucan microparticles are good candidates for mucosal antigen delivery in oral vaccination R De Smet, T Demoor, S Verschuere, M Dullaers, GR Ostroff, G Leclercq, ... Journal of controlled release 172 (3), 671-678, 2013 | 162 | 2013 |
Spectrum and mechanisms of inflammasome activation by chitosan CL Bueter, CK Lee, JP Wang, GR Ostroff, CA Specht, SM Levitz The Journal of immunology 192 (12), 5943-5951, 2014 | 158 | 2014 |
Glucan particles for macrophage targeted delivery of nanoparticles ER Soto, AC Caras, LC Kut, MK Castle, GR Ostroff Journal of drug delivery 2012 (1), 143524, 2012 | 143 | 2012 |
Method for immune system activation by administration of a β (1-3) glucan which is produced by Saccharomyces cerevisiae strain R4 S Jamas, DD Easson Jr, GR Ostroff US Patent 5,504,079, 1996 | 138 | 1996 |
Relative contributions of dectin-1 and complement to immune responses to particulate β-glucans H Huang, GR Ostroff, CK Lee, S Agarwal, S Ram, PA Rice, CA Specht, ... The Journal of Immunology 189 (1), 312-317, 2012 | 128 | 2012 |
Glucan particles for selective delivery of siRNA to phagocytic cells in mice GJ Tesz, M Aouadi, M Prot, SM Nicoloro, E Boutet, SU Amano, A Goller, ... Biochemical Journal 436 (2), 351-362, 2011 | 122 | 2011 |
Glucan drug delivery system and adjuvant S Jamas, GR Ostroff, DD Easson Jr US Patent 5,741,495, 1998 | 115 | 1998 |
Characterization and optimization of the glucan particle-based vaccine platform H Huang, GR Ostroff, CK Lee, CA Specht, SM Levitz Clinical and Vaccine Immunology 20 (10), 1585-1591, 2013 | 96 | 2013 |