Analytical methods for process and product characterization of recombinant adeno-associated virus-based gene therapies AL Gimpel, G Katsikis, S Sha, AJ Maloney, MS Hong, TNT Nguyen, ... Molecular Therapy-Methods & Clinical Development 20, 740-754, 2021 | 116 | 2021 |
Mechanistic model for production of recombinant adeno-associated virus via triple transfection of HEK293 cells TNT Nguyen, S Sha, MS Hong, AJ Maloney, PW Barone, C Neufeld, ... Molecular Therapy Methods & Clinical Development 21, 642-655, 2021 | 62 | 2021 |
Cellular pathways of recombinant adeno-associated virus production for gene therapy S Sha, AJ Maloney, G Katsikis, TNT Nguyen, C Neufeld, J Wolfrum, ... Biotechnology Advances 49, 107764, 2021 | 35 | 2021 |
A virtual Plant for Integrated Continuous Manufacturing of a Carfilzomib drug substance intermediate, part 3: manganese-catalyzed asymmetric Epoxidation, crystallization, and … AJ Maloney, E Içten, G Capellades, MG Beaver, X Zhu, LR Graham, ... Organic Process Research & Development 24 (10), 1891-1908, 2020 | 32 | 2020 |
A virtual Plant for Integrated Continuous Manufacturing of a Carfilzomib drug substance intermediate, part 1: CDI-promoted amide bond formation E Içten, AJ Maloney, MG Beaver, DE Shen, X Zhu, LR Graham, ... Organic Process Research & Development 24 (10), 1861-1875, 2020 | 28 | 2020 |
A virtual Plant for Integrated Continuous Manufacturing of a Carfilzomib drug substance intermediate, part 2: Enone synthesis via a Barbier-type Grignard process E Içten, AJ Maloney, MG Beaver, X Zhu, DE Shen, JA Robinson, ... Organic Process Research & Development 24 (10), 1876-1890, 2020 | 22 | 2020 |
Macroscopic modeling of bioreactors for recombinant protein producing Pichia pastoris in defined medium MS Hong, ML Velez‐Suberbie, AJ Maloney, A Biedermann, KR Love, ... Biotechnology and Bioengineering 118 (3), 1199-1212, 2021 | 19 | 2021 |
A systematic study of the catalytic behavior at enzyme–metal-oxide nanointerfaces AS Campbell, C Dong, A Maloney, J Hardinger, X Hu, F Meng, ... Nano Life 4 (02), 1450005, 2014 | 15 | 2014 |
Emerging enzyme-based technologies for wastewater treatment AJ Maloney, C Dong, AS Campbell, CZ Dinu Green Polymer Chemistry: Biobased Materials and Biocatalysis, 69-85, 2015 | 11 | 2015 |
Automated outlier detection and estimation of missing data J Rhyu, D Bozinovski, AB Dubs, N Mohan, EMC Bende, AJ Maloney, ... Computers & Chemical Engineering 180, 108448, 2024 | 2 | 2024 |
Biomanufacturing and testbed development for the continuous production of monoclonal antibodies D Bozinovski, EM Cummings Bende, AJ Maloney, J Sangerman, AB Dubs, ... | 2 | 2022 |
Immobilization of Biocatalysts onto Nanosupports: Advantages for Green Technologies AS Campbell, AJ Maloney, C Dong, CZ Dinu Biocatalysis and Nanotechnology, 279-321, 2017 | 1 | 2017 |
Multidose Transient Transfection of HEK293 Cells Modulates rAAV2/5 Rep Protein Expression and Influences the Enrichment Fraction of Filled Capsids R Braatz, P Srinivasan, CT Canova, S Sha, TNT Nguyen, J Joseph, ... | | 2024 |
Continuous Manufacturing Testbed Development and Data Release for a Monoclonal Antibody Production Process AB Dubs, D Bozinovski, EMC Bende, AJ Maloney, N Mohan, M Nieves, ... 2023 AIChE Annual Meeting, 2023 | | 2023 |
Modeling of copy number variability in Pichia pastoris AE Lu, AJ Maloney, NC Dalvie, JR Brady, KR Love, JC Love, RD Braatz Biotechnology and Bioengineering 118 (5), 1832-1839, 2021 | | 2021 |
Mathematical Modeling of Gene Therapy Manufacturing T Nguyen, S Sha, AJ Maloney, C Neufeld, J Wolfrum, S Springs, ... 2020 Virtual AIChE Annual Meeting, 2020 | | 2020 |
First-Principles Dynamic Simulation of an Integrated Continuous Biomanufacturing Platform MS Hong, AE Lu, AJ Maloney, EMC Bende, D Bozinovski, J Sangerman, ... 2020 Virtual AIChE Annual Meeting, 2020 | | 2020 |
Process Analytical Technologies for Recombinant Adeno-Associated Virus-Based Gene Therapy A Gimpel, G Katsikis, S Sha, AJ Maloney, MS Hong, T Nguyen, J Wolfrum, ... 2020 Virtual AIChE Annual Meeting, 2020 | | 2020 |
A Mechanistic Analysis of Recombinant Adeno-Associated Virus Productivity in Biomanufacturing S Sha, T Nguyen, AJ Maloney, C Neufeld, G Katsikis, PW Barone, ... 2020 Virtual AIChE Annual Meeting, 2020 | | 2020 |
Process Control Strategy Development for an Integrated Continuous Platform for Monoclonal Antibody Manufacturing AJ Maloney, EMC Bende, D Bozinovski, AE Lu, J Sangerman, MS Hong, ... 2020 Virtual AIChE Annual Meeting, 2020 | | 2020 |