Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist EYT Chien, W Liu, Q Zhao, V Katritch, G Won Han, MA Hanson, L Shi, ... Science 330 (6007), 1091-1095, 2010 | 1340 | 2010 |
The binding sites for cocaine and dopamine in the dopamine transporter overlap T Beuming, J Kniazeff, ML Bergmann, L Shi, L Gracia, K Raniszewska, ... Nature neuroscience 11 (7), 780-789, 2008 | 413 | 2008 |
Time-resolved FRET between GPCR ligands reveals oligomers in native tissues L Albizu, M Cottet, M Kralikova, S Stoev, R Seyer, I Brabet, T Roux, ... Nature chemical biology 6 (8), 587-594, 2010 | 387 | 2010 |
Current perspectives on selective dopamine D3 receptor antagonists as pharmacotherapeutics for addictions and related disorders CA Heidbreder, AH Newman Annals of the New York Academy of Sciences 1187 (1), 4-34, 2010 | 323 | 2010 |
Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype C Martinat, JJ Bacci, T Leete, J Kim, WB Vanti, AH Newman, JH Cha, ... Proceedings of the National Academy of Sciences 103 (8), 2874-2879, 2006 | 268 | 2006 |
Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents AH Newman, P Grundt, MA Nader Journal of medicinal chemistry 48 (11), 3663-3679, 2005 | 216 | 2005 |
Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants LK Henry, JR Field, EM Adkins, ML Parnas, RA Vaughan, MF Zou, ... Journal of Biological Chemistry 281 (4), 2012-2023, 2006 | 207 | 2006 |
Molecular determinants of selectivity and efficacy at the dopamine D3 receptor AH Newman, T Beuming, AK Banala, P Donthamsetti, K Pongetti, ... Journal of medicinal chemistry 55 (15), 6689-6699, 2012 | 186 | 2012 |
The novel dopamine D3 receptor antagonist NGB 2904 inhibits cocaine's rewarding effects and cocaine-induced reinstatement of drug-seeking behavior in rats ZX Xi, AH Newman, JG Gilbert, AC Pak, XQ Peng, CR Ashby, L Gitajn, ... Neuropsychopharmacology 31 (7), 1393-1405, 2006 | 175 | 2006 |
Dopamine agonist-induced yawning in rats: a dopamine D3 receptor-mediated behavior GT Collins, JM Witkin, AH Newman, KA Svensson, P Grundt, J Cao, ... Journal of Pharmacology and experimental therapeutics 314 (1), 310-319, 2005 | 168 | 2005 |
Synthesis and evaluation of optically pure [3H]‐(+)‐pentazocine, a highly potent and selective radioligand for σ receptors BR de Costa, WD Bowen, SB Hellewell, JM Walker, A Thurkauf, ... FEBS letters 251 (1-2), 53-58, 1989 | 164 | 1989 |
Acute administration of SB‐277011A, NGB 2904, or BP 897 inhibits cocaine cue‐induced reinstatement of drug‐seeking behavior in rats: Role of dopamine D3 receptors JG Gilbert, AH Newman, EL Gardner, CR Ashby Jr, CA Heidbreder, ... Synapse 57 (1), 17-28, 2005 | 162 | 2005 |
Novel heterocyclic trans olefin analogues of N-{4-[4-(2, 3-dichlorophenyl) piperazin-1-yl] butyl} arylcarboxamides as selective probes with high affinity for the dopamine D3 … P Grundt, EE Carlson, J Cao, CJ Bennett, E McElveen, M Taylor, ... Journal of medicinal chemistry 48 (3), 839-848, 2005 | 162 | 2005 |
Dissociable control of impulsivity in rats by dopamine d2/3 receptors in the core and shell subregions of the nucleus accumbens M Besson, D Belin, R McNamara, DEH Theobald, A Castel, VL Beckett, ... Neuropsychopharmacology 35 (2), 560-569, 2010 | 159 | 2010 |
Missense dopamine transporter mutations associate with adult parkinsonism and ADHD FH Hansen, T Skjørringe, S Yasmeen, NV Arends, MA Sahai, K Erreger, ... The Journal of clinical investigation 124 (7), 3107-3120, 2014 | 156 | 2014 |
The N terminus of monoamine transporters is a lever required for the action of amphetamines S Sucic, S Dallinger, B Zdrazil, R Weissensteiner, TN Jørgensen, M Holy, ... Journal of Biological Chemistry 285 (14), 10924-10938, 2010 | 154 | 2010 |
Medication discovery for addiction: translating the dopamine D3 receptor hypothesis AH Newman, BL Blaylock, MA Nader, J Bergman, DR Sibley, P Skolnick Biochemical pharmacology 84 (7), 882-890, 2012 | 150 | 2012 |
Modulation of high impulsivity and attentional performance in rats by selective direct and indirect dopaminergic and noradrenergic receptor agonists ABP Fernando, D Economidou, DE Theobald, MF Zou, AH Newman, ... Psychopharmacology 219, 341-352, 2012 | 150 | 2012 |
Sigma receptors negatively modulate agonist-stimulated phosphoinositide metabolism in rat brain W Bowen, B Kirschner, S Hellewell, A Newman, K Rice Problems of Drug Dependence 1988, 354, 1988 | 150 | 1988 |
R-modafinil (armodafinil): a unique dopamine uptake inhibitor and potential medication for psychostimulant abuse CJ Loland, M Mereu, OM Okunola, J Cao, TE Prisinzano, S Mazier, ... Biological psychiatry 72 (5), 405-413, 2012 | 149 | 2012 |