Immortalization of primary microglia: a new platform to study HIV regulation in the central nervous system Y Garcia-Mesa, TR Jay, MA Checkley, B Luttge, C Dobrowolski, ... Journal of neurovirology 23, 47-66, 2017 | 189 | 2017 |
Estrogen receptor-1 is a key regulator of HIV-1 latency that imparts gender-specific restrictions on the latent reservoir B Das, C Dobrowolski, B Luttge, S Valadkhan, N Chomont, R Johnston, ... Proceedings of the National Academy of Sciences 115 (33), E7795-E7804, 2018 | 155 | 2018 |
Negative elongation factor is required for the maintenance of proviral latency but does not induce promoter-proximal pausing of RNA polymerase II on the HIV long terminal repeat JK Jadlowsky, JY Wong, AC Graham, C Dobrowolski, RL Devor, ... Molecular and cellular biology, 2014 | 115 | 2014 |
Toll-like receptor 3 activation selectively reverses HIV latency in microglial cells D Alvarez-Carbonell, Y Garcia-Mesa, S Milne, B Das, C Dobrowolski, ... Retrovirology 14, 1-25, 2017 | 106 | 2017 |
Multiple histone lysine methyltransferases are required for the establishment and maintenance of HIV-1 latency K Nguyen, B Das, C Dobrowolski, J Karn MBio 8 (1), 10.1128/mbio. 00133-17, 2017 | 106 | 2017 |
Phosphorylation of CDK9 at Ser175 Enhances HIV Transcription and Is a Marker of Activated P-TEFb in CD4+ T Lymphocytes UR Mbonye, G Gokulrangan, M Datt, C Dobrowolski, M Cooper, ... PLoS pathogens 9 (5), e1003338, 2013 | 95 | 2013 |
Sex-based differences in human immunodeficiency virus type 1 reservoir activity and residual immune activation EP Scully, M Gandhi, R Johnston, R Hoh, A Lockhart, C Dobrowolski, ... The Journal of infectious diseases 219 (7), 1084-1094, 2019 | 89 | 2019 |
The Histone Deacetylase Inhibitor Vorinostat (SAHA) Increases the Susceptibility of Uninfected CD4+ T Cells to HIV by Increasing the Kinetics and Efficiency of … MB Lucera, CA Tilton, H Mao, C Dobrowolski, CO Tabler, AA Haqqani, ... Journal of virology 88 (18), 10803-10812, 2014 | 88 | 2014 |
Species-dependent in vivo mRNA delivery and cellular responses to nanoparticles MZC Hatit, MP Lokugamage, CN Dobrowolski, K Paunovska, H Ni, ... Nature nanotechnology 17 (3), 310-318, 2022 | 80 | 2022 |
Safety and virologic impact of the IL-15 superagonist N-803 in people living with HIV: a phase 1 trial JS Miller, ZB Davis, E Helgeson, C Reilly, A Thorkelson, J Anderson, ... Nature medicine 28 (2), 392-400, 2022 | 68 | 2022 |
Methamphetamine activates nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and induces human immunodeficiency virus (HIV) transcription in human … ES Wires, D Alvarez, C Dobrowolski, Y Wang, M Morales, J Karn, ... Journal of neurovirology 18, 400-410, 2012 | 66 | 2012 |
Nanoparticle single-cell multiomic readouts reveal that cell heterogeneity influences lipid nanoparticle-mediated messenger RNA delivery C Dobrowolski, K Paunovska, E Schrader Echeverri, D Loughrey, ... Nature Nanotechnology 17 (8), 871-879, 2022 | 58 | 2022 |
Short chain fatty acids potently induce latent HIV-1 in T-cells by activating P-TEFb and multiple histone modifications B Das, C Dobrowolski, AM Shahir, Z Feng, X Yu, J Sha, NF Bissada, ... Virology 474, 65-81, 2015 | 57 | 2015 |
Therapeutic RNA delivery for COVID and other diseases C Dobrowolski, K Paunovska, MZC Hatit, MP Lokugamage, JE Dahlman Advanced healthcare materials 10 (15), 2002022, 2021 | 42 | 2021 |
Entry of polarized effector cells into quiescence forces HIV latency C Dobrowolski, S Valadkhan, AC Graham, M Shukla, A Ciuffi, A Telenti, ... MBio 10 (2), 10.1128/mbio. 00337-19, 2019 | 42 | 2019 |
A phase 1/2 randomized, placebo-controlled trial of romidespin in persons with HIV-1 on suppressive antiretroviral therapy DK McMahon, L Zheng, JC Cyktor, E Aga, BJ Macatangay, C Godfrey, ... The Journal of infectious diseases 224 (4), 648-656, 2021 | 40 | 2021 |
The glucocorticoid receptor is a critical regulator of HIV latency in human microglial cells D Alvarez-Carbonell, F Ye, N Ramanath, C Dobrowolski, J Karn Journal of Neuroimmune Pharmacology 14, 94-109, 2019 | 35 | 2019 |
The Transcriptional Response to Lung-Targeting Lipid Nanoparticles in Vivo A Radmand, MP Lokugamage, H Kim, C Dobrowolski, R Zenhausern, ... Nano letters 23 (3), 993-1002, 2023 | 33 | 2023 |
Sex differences in human immunodeficiency virus persistence and reservoir size during aging S Gianella, SA Rawlings, C Dobrowolski, M Nakazawa, A Chaillon, ... Clinical Infectious Diseases 75 (1), 73-80, 2022 | 33 | 2022 |
Substituting racemic ionizable lipids with stereopure ionizable lipids can increase mRNA delivery AJDS Sanchez, K Zhao, SG Huayamares, MZC Hatit, MP Lokugamage, ... Journal of Controlled Release 353, 270-277, 2023 | 29 | 2023 |