| Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma PW Lewis, MM Müller, MS Koletsky, F Cordero, S Lin, LA Banaszynski, ... Science 340 (6134), 857-861, 2013 | 1305 | 2013 |
| Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations P Buczkowicz, C Hoeman, P Rakopoulos, S Pajovic, L Letourneau, ... Nature genetics 46 (5), 451-456, 2014 | 630 | 2014 |
| Paediatric and adult glioblastoma: multiform (epi) genomic culprits emerge D Sturm, S Bender, DTW Jones, P Lichter, J Grill, O Becher, C Hawkins, ... Nature Reviews Cancer 14 (2), 92-107, 2014 | 611 | 2014 |
| PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo D Hambardzumyan, OJ Becher, MK Rosenblum, PP Pandolfi, ... Genes & development 22 (4), 436-448, 2008 | 554 | 2008 |
| Pediatric high-grade glioma: biologically and clinically in need of new thinking C Jones, MA Karajannis, DTW Jones, MW Kieran, M Monje, SJ Baker, ... Neuro-oncology 19 (2), 153-161, 2017 | 375 | 2017 |
| Reasons for pediatrician nonadherence to asthma guidelines MD Cabana, CS Rand, OJ Becher, HR Rubin Archives of pediatrics & adolescent medicine 155 (9), 1057-1062, 2001 | 336 | 2001 |
| Histopathological spectrum of paediatric diffuse intrinsic pontine glioma: diagnostic and therapeutic implications P Buczkowicz, U Bartels, E Bouffet, O Becher, C Hawkins Acta neuropathologica 128, 573-581, 2014 | 318 | 2014 |
| Genetically engineered models have advantages over xenografts for preclinical studies OJ Becher, EC Holland Cancer research 66 (7), 3355-3359, 2006 | 307 | 2006 |
| Modeling adult gliomas using RCAS/t-va technology D Hambardzumyan, NM Amankulor, KY Helmy, OJ Becher, EC Holland Translational oncology 2 (2), 89-IN6, 2009 | 272 | 2009 |
| Sonic hedgehog pathway activation is induced by acute brain injury and regulated by injury-related inflammation NM Amankulor, D Hambardzumyan, SM Pyonteck, OJ Becher, JA Joyce, ... Journal of Neuroscience 29 (33), 10299-10308, 2009 | 241 | 2009 |
| Gli activity correlates with tumor grade in platelet-derived growth factor–induced gliomas OJ Becher, D Hambardzumyan, EI Fomchenko, H Momota, L Mainwaring, ... Cancer research 68 (7), 2241-2249, 2008 | 217 | 2008 |
| Integrated proteogenomic characterization across major histological types of pediatric brain cancer F Petralia, N Tignor, B Reva, M Koptyra, S Chowdhury, D Rykunov, A Krek, ... Cell 183 (7), 1962-1985. e31, 2020 | 215 | 2020 |
| Preclinical evaluation of radiation and perifosine in a genetically and histologically accurate model of brainstem glioma OJ Becher, D Hambardzumyan, TR Walker, K Helmy, J Nazarian, ... Cancer research 70 (6), 2548-2557, 2010 | 186 | 2010 |
| PD-0332991, a CDK4/6 inhibitor, significantly prolongs survival in a genetically engineered mouse model of brainstem glioma KL Barton, K Misuraca, F Cordero, E Dobrikova, HD Min, M Gromeier, ... PloS one 8 (10), e77639, 2013 | 173 | 2013 |
| Histone H3.3K27M Represses p16 to Accelerate Gliomagenesis in a Murine Model of DIPG FJ Cordero, Z Huang, C Grenier, X He, G Hu, RE McLendon, SK Murphy, ... Molecular Cancer Research 15 (9), 1243-1254, 2017 | 159 | 2017 |
| Pre-clinical study of panobinostat in xenograft and genetically engineered murine diffuse intrinsic pontine glioma models T Hennika, G Hu, NG Olaciregui, KL Barton, A Ehteda, A Chitranjan, ... PloS one 12 (1), e0169485, 2017 | 159 | 2017 |
| Cancer stem cells and survival pathways D Hambardzumyan, OJ Becher, EC Holland Cell Cycle 7 (10), 1371-1378, 2008 | 141 | 2008 |
| The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models N Martínez-Vélez, M Garcia-Moure, M Marigil, M González-Huarriz, ... Nature communications 10 (1), 2235, 2019 | 132 | 2019 |
| Children are not just little adults: recent advances in understanding of diffuse intrinsic pontine glioma biology KM Schroeder, CM Hoeman, OJ Becher Pediatric research 75 (1), 205-209, 2014 | 102 | 2014 |
| ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis CM Hoeman, FJ Cordero, G Hu, K Misuraca, MM Romero, HJ Cardona, ... Nature communications 10 (1), 1023, 2019 | 100 | 2019 |
