Tumor cell-produced matrix metalloproteinase 9 (MMP-9) drives malignant progression and metastasis of basal-like triple negative breast cancer C Mehner, A Hockla, E Miller, S Ran, DC Radisky, ES Radisky Oncotarget 5 (9), 2736, 2014 | 417 | 2014 |
Tumor cell expression of MMP3 as a prognostic factor for poor survival in pancreatic, pulmonary, and mammary carcinoma C Mehner, E Miller, A Nassar, WR Bamlet, ES Radisky, DC Radisky Genes & cancer 6 (11-12), 480, 2015 | 114 | 2015 |
PEGylation extends circulation half-life while preserving in vitro and in vivo activity of tissue inhibitor of metalloproteinases-1 (TIMP-1) J Batra, J Robinson, C Mehner, A Hockla, E Miller, DC Radisky, ... PLoS One 7 (11), e50028, 2012 | 69 | 2012 |
Tumor cell–derived MMP3 Orchestrates Rac1b and tissue alterations that promote pancreatic adenocarcinoma C Mehner, E Miller, D Khauv, A Nassar, AL Oberg, WR Bamlet, L Zhang, ... Molecular Cancer Research 12 (10), 1430-1439, 2014 | 68 | 2014 |
Platelet‐derived growth factor regulates YAP transcriptional activity via Src family kinase dependent tyrosine phosphorylation RL Smoot, NW Werneburg, T Sugihara, MC Hernandez, L Yang, ... Journal of cellular biochemistry 119 (1), 824-836, 2018 | 65 | 2018 |
EGFR as a prognostic biomarker and therapeutic target in ovarian cancer: evaluation of patient cohort and literature review C Mehner, AL Oberg, KM Goergen, KR Kalli, MJ Maurer, A Nassar, ... Genes & cancer 8 (5-6), 589, 2017 | 59 | 2017 |
Matrix metalloproteinase-10/TIMP-2 structure and analyses define conserved core interactions and diverse exosite interactions in MMP/TIMP complexes J Batra, AS Soares, C Mehner, ES Radisky PLoS one 8 (9), e75836, 2013 | 47 | 2013 |
A 3D‐bioprinted vascularized glioblastoma‐on‐a‐chip for studying the impact of simulated microgravity as a novel pre‐clinical approach in brain tumor therapy G Silvani, C Basirun, H Wu, C Mehner, K Poole, P Bradbury, J Chou Advanced therapeutics 4 (11), 2100106, 2021 | 39 | 2021 |
Triggering the landslide: The tumor-promotional effects of myofibroblasts C Mehner, DC Radisky Experimental cell research 319 (11), 1657-1662, 2013 | 38 | 2013 |
PRSS3/Mesotrypsin and kallikrein-related peptidase 5 are associated with poor prognosis and contribute to tumor cell invasion and growth in lung adenocarcinoma H Ma, A Hockla, C Mehner, M Coban, N Papo, DC Radisky, ES Radisky Scientific reports 9 (1), 1844, 2019 | 32 | 2019 |
Serine protease inhibitor Kazal type 1 (SPINK1) drives proliferation and anoikis resistance in a subset of ovarian cancers C Mehner, AL Oberg, KR Kalli, A Nassar, A Hockla, D Pendlebury, ... Oncotarget 6 (34), 35737, 2015 | 30 | 2015 |
Bad tumors made worse: SPINK1 C Mehner, ES Radisky Frontiers in cell and developmental biology 7, 10, 2019 | 21 | 2019 |
MYC is a crucial mediator of TGFβ-induced invasion in basal breast cancer MA Cichon, ME Moruzzi, TA Shqau, E Miller, C Mehner, SP Ethier, ... Cancer research 76 (12), 3520-3530, 2016 | 20 | 2016 |
Targeting an autocrine IL-6–SPINK1 signaling axis to suppress metastatic spread in ovarian clear cell carcinoma C Mehner, E Miller, A Hockla, M Coban, SJ Weroha, DC Radisky, ... Oncogene 39 (42), 6606-6618, 2020 | 17 | 2020 |
NanoString-based breast cancer risk prediction for women with sclerosing adenosis SJ Winham, C Mehner, EP Heinzen, BT Broderick, M Stallings-Mann, ... Breast Cancer Research and Treatment 166, 641-650, 2017 | 14 | 2017 |
Activity-based protein profiling reveals active serine proteases that drive malignancy of human ovarian clear cell carcinoma C Mehner, A Hockla, M Coban, B Madden, R Estrada, DC Radisky, ... Journal of Biological Chemistry 298 (8), 2022 | 6 | 2022 |
Testing 3D printed biological platform for advancing simulated microgravity and space mechanobiology research G Silvani, P Bradbury, C Basirun, C Mehner, D Zalli, K Poole, J Chou npj Microgravity 8 (1), 19, 2022 | 6 | 2022 |
A 3D‐Bioprinted Vascularized Glioblastoma‐on‐a‐Chip for Studying the Impact of Simulated Microgravity as a Novel Pre‐Clinical Approach in Brain Tumor Therapy (Adv. Therap. 11/2021) G Silvani, C Basirun, H Wu, C Mehner, K Poole, P Bradbury, J Chou Advanced Therapeutics 4 (11), 2170033, 2021 | 6 | 2021 |
Real versus simulated galactic cosmic radiation for investigating cancer risk in the hematopoietic system - are we comparing apples to apples? C Mehner, S Krishnan, J Chou, ML Freeman, WD Freeman, T Patel, ... Life Sciences in Space Research, 2021 | 5 | 2021 |
Engineering TIMP-1 for selective MMP inhibition and future use as a protein therapeutic. C Mehner, J Batra, J Robinson, DC Radisky, ES Radisky Cancer Research 73 (8_Supplement), 5069-5069, 2013 | 2 | 2013 |