| Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells: metabolic basis and potential … B Tan, DA Young, ZH Lu, T Wang, TI Meier, RL Shepard, K Roth, Y Zhai, ... Journal of Biological Chemistry 288 (5), 3500-3511, 2013 | 207 | 2013 |
| The folate pathway inhibitor pemetrexed pleiotropically enhances effects of cancer immunotherapy DA Schaer, S Geeganage, N Amaladas, ZH Lu, ER Rasmussen, A Sonyi, ... Clinical Cancer Research 25 (23), 7175-7188, 2019 | 106 | 2019 |
| Effects of tirzepatide, a dual GIP and GLP-1 RA, on lipid and metabolite profiles in subjects with type 2 diabetes V Pirro, KD Roth, Y Lin, JA Willency, PL Milligan, JM Wilson, G Ruotolo, ... The Journal of Clinical Endocrinology & Metabolism 107 (2), 363-378, 2022 | 59 | 2022 |
| Inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, leads to altered carbohydrate metabolism in cancer cells B Tan, S Dong, RL Shepard, L Kays, KD Roth, S Geeganage, MS Kuo, ... Journal of Biological Chemistry 290 (25), 15812-15824, 2015 | 54 | 2015 |
| Nucleotides released from palmitate-activated murine macrophages attract neutrophils TH Tam, KL Chan, P Boroumand, Z Liu, JT Brozinick, HH Bui, K Roth, ... Journal of Biological Chemistry 295 (15), 4902-4911, 2020 | 26 | 2020 |
| Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective … KR Fales, FG Njoroge, HB Brooks, S Thibodeaux, A Torrado, C Si, JL Toth, ... Journal of Medicinal Chemistry 60 (23), 9599-9616, 2017 | 25 | 2017 |
| Synthesis of Diverse N-Acryloyl Azetidines and Evaluation of Their Enhanced Thiol Reactivities MD Palkowitz, B Tan, H Hu, K Roth, RA Bauer Organic letters 19 (9), 2270-2273, 2017 | 25 | 2017 |
| Against all odds: a qualitative study of rehabilitation of persons with spinal cord injury in Afghanistan M Michael, K Roth Spinal Cord 50 (12), 864-868, 2012 | 21 | 2012 |
| Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models HB Brooks, TI Meier, S Geeganage, KR Fales, KJ Thrasher, SA Konicek, ... Scientific Reports 8 (1), 15458, 2018 | 13 | 2018 |
| Sex differences in insulin sensitivity are related to muscle tissue acylcarnitine but not subcellular lipid distribution JL Broussard, L Perreault, E Macias, SA Newsom, K Harrison, HH Bui, ... Obesity 29 (3), 550-561, 2021 | 12 | 2021 |
| Abstract LB-274: identification and characterization of LY3410738, a novel covalent inhibitor of cancer-associated mutant Isocitrate Dehydrogenase 1 (IDH1) N Brooks, R DeWalt, S Boulet, ZH Lu, L Kays, R Cavitt, S Gomez, ... Cancer Research 79 (13_Supplement), LB-274-LB-274, 2019 | 11 | 2019 |
| 2-Hydroxy-oleic acid does not activate sphingomyelin synthase activity B Lou, Q Liu, J Hou, I Kabir, P Liu, T Ding, J Dong, M Mo, D Ye, Y Chen, ... Journal of Biological Chemistry 293 (47), 18328-18336, 2018 | 11 | 2018 |
| LY3410738, a novel inhibitor of mutant IDH1 is more effective than Ivosidenib and potentiates antileukemic activity of standard chemotherapy in preclinical models of acute … V Salama, N Brooks, A Skwarska, L Kays, P Milligan, K Newell, K Roth, ... Cancer Research 80 (16_Supplement), 6417-6417, 2020 | 9 | 2020 |
| Development of ion pairing LC-MS/MS method for itaconate and cis-aconitate in cell extract and cell media B Tan, S Malu, KD Roth Journal of Chromatography B 1146, 122120, 2020 | 8 | 2020 |
| Effects of tirzepatide, a novel dual GIP and GLP-1 receptor agonist, on lipid profiling in patients with type 2 diabetes G Ruotolo, KD Roth, PL Milligan, Y Lin, JM Wilson, V Pirro, KL Duffin, ... European Heart Journal 41 (Supplement_2), ehaa946. 3056, 2020 | 6 | 2020 |
| P1. 04-07 Pemetrexed Enhances Anti-Tumor Efficacy of PD-L1 blockade by Promoting Intra-Tumor Immune Response via Tumor and T Cell-Intrinsic Mechanisms D Schaer, S Geeganage, N Amaladas, ZH Lu, E Rasmussen, A Sonyi, ... Journal of Thoracic Oncology 13 (10), S527, 2018 | 3 | 2018 |
| Tryptophan Metabolism Plays a Central Role in Immunosuppression S Geeganage, L Sams, J Henry, F Dorsey, K Roth, A Nikolayev, ... Cancer Research 79 (13_Supplement), 2187-2187, 2019 | 2 | 2019 |
| 2062-P: Improvement in Sphingolipids after Combined Weight Loss and Exercise Training in Adults with Obesity and Prediabetes JL Broussard, DE Kahn, SA Newsom, JT Brozinick, H Bui, KD Roth, ... Diabetes 68 (Supplement_1), 2019 | 1 | 2019 |
| Use of Plasma Metabolomics and Lipidomics for the Diagnosis of Nonalcoholic Fatty Liver Disease in Type 2 Diabetes F Bril, S Kalavalapalli, KL Duffin, ML Hartman, Y Chen, Q Yang, JV Haas, ... Diabetes 67 (Supplement_1), 2018 | 1 | 2018 |
| SHIP1 modulation and proteome characterization of microglia E Ahat, Z Shi, S Chu, HH Bui, ER Mason, DM Soni, KD Roth, ... Journal of Proteomics, 105198, 2024 | | 2024 |
