Rational design of bisphosphonate lipid-like materials for mRNA delivery to the bone microenvironment L Xue, N Gong, SJ Shepherd, X Xiong, X Liao, X Han, G Zhao, C Song, ... Journal of the American Chemical Society 144 (22), 9926-9937, 2022 | 83 | 2022 |
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy KL Swingle, HC Safford, HC Geisler, AG Hamilton, AS Thatte, ... Journal of the American Chemical Society 145 (8), 4691-4706, 2023 | 71 | 2023 |
Nanoparticle protein corona: from structure and function to therapeutic targeting G Bashiri, MS Padilla, KL Swingle, SJ Shepherd, MJ Mitchell, K Wang Lab on a Chip 23 (6), 1432-1466, 2023 | 65 | 2023 |
Rational design of anti‐inflammatory lipid nanoparticles for mRNA delivery H Zhang, X Han, MG Alameh, SJ Shepherd, MS Padilla, L Xue, ... Journal of Biomedical Materials Research Part A 110 (5), 1101-1108, 2022 | 33 | 2022 |
Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines SJ Shepherd, X Han, AJ Mukalel, R El-Mayta, AS Thatte, J Wu, MS Padilla, ... Proceedings of the National Academy of Sciences 120 (33), e2303567120, 2023 | 30 | 2023 |
Preparation of asymmetrical polyynes by a solid-supported Glaser–Hay reaction JS Lampkowski, CE Durham, MS Padilla, DD Young Organic & Biomolecular Chemistry 13 (2), 424-427, 2015 | 23 | 2015 |
Lipid Nanoparticle Delivery of Small Proteins for Potent In Vivo RAS Inhibition RM Haley, A Chan, MM Billingsley, N Gong, MS Padilla, EH Kim, H Wang, ... ACS applied materials & interfaces 15 (18), 21877-21892, 2023 | 19 | 2023 |
Antigen presenting cell mimetic lipid nanoparticles for rapid mRNA CAR T cell cancer immunotherapy AE Metzloff, MS Padilla, N Gong, MM Billingsley, X Han, M Merolle, D Mai, ... Advanced Materials, 2313226, 2024 | 17 | 2024 |
Expanding the structural diversity of hydrophobic ionic liquids: Physicochemical properties and toxicity of Gemini ionic liquids MS Padilla, C Bertz, N Berdusco, S Mecozzi Green Chemistry 23 (12), 4375-4385, 2021 | 16 | 2021 |
Delivery of plasmid DNA by ionizable lipid nanoparticles to induce CAR expression in T cells PHDM Prazeres, H Ferreira, PAC Costa, W da Silva, MT Alves, M Padilla, ... International Journal of Nanomedicine, 5891-5904, 2023 | 14 | 2023 |
Investigation of copper-free alkyne/azide 1, 3-dipolar cycloadditions using microwave irradiation LE Chatkewitz, JF Halonski, MS Padilla, DD Young Bioorganic & medicinal chemistry letters 28 (2), 81-84, 2018 | 14 | 2018 |
Predictive high-throughput platform for dual screening of mRNA lipid nanoparticle blood–brain barrier transfection and crossing EL Han, MS Padilla, R Palanki, D Kim, K Mrksich, JJ Li, S Tang, IC Yoon, ... Nano Letters 24 (5), 1477-1486, 2024 | 13 | 2024 |
Photosensitive GFP mutants containing an azobenzene unnatural amino acid MS Padilla, DD Young Bioorganic & medicinal chemistry letters 25 (3), 470-473, 2015 | 13 | 2015 |
Testing the in vitro and in vivo efficiency of mRNA-lipid nanoparticles formulated by microfluidic mixing R El-Mayta, MS Padilla, MM Billingsley, X Han, MJ Mitchell Journal of Visualized Experiments, 2023 | 12 | 2023 |
Oxidized mRNA Lipid Nanoparticles for In Situ Chimeric Antigen Receptor Monocyte Engineering AJ Mukalel, AG Hamilton, MM Billingsley, J Li, AS Thatte, X Han, ... Advanced Functional Materials, 2312038, 2024 | 7 | 2024 |
Influence of ionizable lipid tail length on lipid nanoparticle delivery of mRNA of varying length K Mrksich, MS Padilla, RA Joseph, EL Han, D Kim, R Palanki, J Xu, ... Journal of Biomedical Materials Research Part A, 2024 | 6 | 2024 |
Synthesis and incorporation of a caged tyrosine amino acid possessing a bioorthogonal handle MS Padilla, CA Farley, LE Chatkewitz, DD Young Tetrahedron letters 57 (42), 4709-4712, 2016 | 5 | 2016 |
Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo X Han, MG Alameh, N Gong, L Xue, M Ghattas, G Bojja, J Xu, G Zhao, ... Nature Chemistry, 1-11, 2024 | 3 | 2024 |
EGFR-targeted ionizable lipid nanoparticles enhance in vivo mRNA delivery to the placenta HC Geisler, AA Ghalsasi, HC Safford, KL Swingle, AS Thatte, AJ Mukalel, ... Journal of Controlled Release 371, 455-469, 2024 | 3 | 2024 |
Probing Ionic Liquid Toxicity through Biophysical and Computational Methods MS Padilla, S Mecozzi Journal of Molecular Liquids, 123886, 2023 | 1 | 2023 |