CDK inhibitors: positive and negative regulators of G1-phase progression CJ Sherr, JM Roberts Genes & development 13 (12), 1501-1512, 1999 | 7819 | 1999 |
Inhibitors of mammalian G1 cyclin-dependent kinases CJ Sherr, JM Roberts Genes and development 9 (10), 1149-1163, 1995 | 4533 | 1995 |
Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals K Polyak, MH Lee, H Erdjument-Bromage, A Koff, JM Roberts, P Tempst, ... Cell 78 (1), 59-66, 1994 | 3080 | 1994 |
p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest. K Polyak, JY Kato, MJ Solomon, CJ Sherr, J Massague, JM Roberts, ... Genes & development 8 (1), 9-22, 1994 | 2849 | 1994 |
A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27Kip1-deficient mice ML Fero, M Rivkin, M Tasch, P Porter, CE Carow, E Firpo, K Polyak, ... Cell 85 (5), 733-744, 1996 | 1830 | 1996 |
Human Cyclin E, a Nuclear Protein Essential for the G1-to-S Phase Transition M Ohtsubo, AM Theodoras, J Schumacher, JM Roberts, M Pagano Molecular and cellular biology 15 (5), 2612-2624, 1995 | 1611 | 1995 |
The p21Cip1 and p27Kip1 CDK ‘inhibitors’ are essential activators of cyclin D‐dependent kinases in murine fibroblasts M Cheng, P Olivier, JA Diehl, M Fero, MF Roussel, JM Roberts, CJ Sherr The EMBO journal, 1999 | 1490 | 1999 |
Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle A Koff, A Giordano, D Desai, K Yamashita, JW Harper, S Elledge, ... Science 257 (5077), 1689-1694, 1992 | 1459 | 1992 |
CDK inhibitors: cell cycle regulators and beyond A Besson, SF Dowdy, JM Roberts Developmental cell 14 (2), 159-169, 2008 | 1421 | 2008 |
Living with or without cyclins and cyclin-dependent kinases CJ Sherr, JM Roberts Genes & development 18 (22), 2699-2711, 2004 | 1389 | 2004 |
lnterleukin-2-mediated elimination of the p27Kipl cyclin-dependent kinase inhibitor prevented by rapamycin J Nourse, E Firpo, WM Flanagan, S Coats, K Polyak, MH Lee, J Massague, ... Nature 372 (6506), 570-573, 1994 | 1229 | 1994 |
Cyclin E-CDK2 is a regulator of p27Kip1. RJ Sheaff, M Groudine, M Gordon, JM Roberts, BE Clurman Genes & development 11 (11), 1464-1478, 1997 | 1205 | 1997 |
Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients PL Porter, KE Malone, PJ Heagerty, GM Alexander, LA Gatti, EJ Firpo, ... Nature medicine 3 (2), 222-225, 1997 | 1144 | 1997 |
Cyclin-dependent regulation of G1 in mammalian fibroblasts M Ohtsubo, JM Roberts Science 259 (5103), 1908-1912, 1993 | 1035 | 1993 |
The murine gene p27Kip1 is haplo-insufficient for tumour suppression ML Fero, E Randel, KE Gurley, JM Roberts, CJ Kemp Nature 396 (6707), 177-180, 1998 | 1016 | 1998 |
Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family A Koff, F Cross, A Fisher, J Schumacher, K Leguellec, M Philippe, ... Cell 66 (6), 1217-1228, 1991 | 938 | 1991 |
Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle S Coats, WM Flanagan, J Nourse, JM Roberts Science 272 (5263), 877-880, 1996 | 920 | 1996 |
The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse R Hakem, JL De La Pompa, C Sirard, R Mo, M Woo, A Hakem, ... Cell 85 (7), 1009-1023, 1996 | 832 | 1996 |
Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-β A Koff, M Ohtsuki, K Polyak, JM Roberts, J Massagué Science 260 (5107), 536-539, 1993 | 798 | 1993 |
Fibrillar collagen inhibits arterial smooth muscle proliferation through regulation of Cdk2 inhibitors H Koyama, EW Raines, KE Bornfeldt, JM Roberts, R Ross Cell 87 (6), 1069-1078, 1996 | 662 | 1996 |