| Structural basis of Smoothened regulation by its extracellular domains EFX Byrne, R Sircar, PS Miller, G Hedger, G Luchetti, S Nachtergaele, ... Nature 535 (7613), 517-522, 2016 | 354 | 2016 |
| Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling G Luchetti, R Sircar, JH Kong, S Nachtergaele, A Sagner, EFX Byrne, ... Elife 5, e20304, 2016 | 229 | 2016 |
| Cholesterol accessibility at the ciliary membrane controls hedgehog signaling M Kinnebrew, EJ Iverson, BB Patel, GV Pusapati, JH Kong, KA Johnson, ... Elife 8, e50051, 2019 | 115 | 2019 |
| Shigella ubiquitin ligase IpaH7. 8 targets gasdermin D for degradation to prevent pyroptosis and enable infection G Luchetti, JL Roncaioli, RA Chavez, AF Schubert, EM Kofoed, R Reja, ... Cell Host & Microbe 29 (10), 1521-1530. e10, 2021 | 103 | 2021 |
| Ric1-Rgp1 complex is a guanine nucleotide exchange factor for the late Golgi Rab6A GTPase and an effector of the medial Golgi Rab33B GTPase GV Pusapati, G Luchetti, SR Pfeffer Journal of Biological Chemistry 287 (50), 42129-42137, 2012 | 72 | 2012 |
| Multiple ligand binding sites regulate the Hedgehog signal transducer Smoothened in vertebrates EFX Byrne, G Luchetti, R Rohatgi, C Siebold Current opinion in cell biology 51, 81-88, 2018 | 67 | 2018 |
| Novel three-component synthesis and antiproliferative properties of diversely functionalized pyrrolines IV Magedov, G Luchetti, NM Evdokimov, M Manpadi, WFA Steelant, ... Bioorganic & medicinal chemistry letters 18 (4), 1392-1396, 2008 | 67 | 2008 |
| G protein–coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog GV Pusapati, JH Kong, BB Patel, M Gouti, A Sagner, R Sircar, G Luchetti, ... Science Signaling 11 (516), eaao5749, 2018 | 63 | 2018 |
| Bulbispermine: a crinine‐type amaryllidaceae alkaloid exhibiting cytostatic activity toward apoptosis‐resistant glioma cells G Luchetti, R Johnston, V Mathieu, F Lefranc, K Hayden, A Andolfi, ... ChemMedChem 7 (5), 815-822, 2012 | 60 | 2012 |
| Patched 1 reduces the accessibility of cholesterol in the outer leaflet of membranes M Kinnebrew, G Luchetti, R Sircar, S Frigui, LV Viti, T Naito, F Beckert, ... Elife 10, e70504, 2021 | 38 | 2021 |
| Tracking the subcellular fate of 20 (s)-hydroxycholesterol with click chemistry reveals a transport pathway to the Golgi SM Peyrot, S Nachtergaele, G Luchetti, LK Mydock-McGrane, H Fujiwara, ... Journal of Biological Chemistry 289 (16), 11095-11110, 2014 | 27 | 2014 |
| S. Van slambrouck, P. Tongwa, MY Antipin and A. Kornienko IV Magedov, G Luchetti, NM Evdokimov, M Manpadi, WFA Steelant Bioorg. Med. Chem. Lett 18, 1392, 2008 | 26 | 2008 |
| Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain M Kinnebrew, RE Woolley, TB Ansell, EFX Byrne, S Frigui, G Luchetti, ... Science Advances 8 (22), eabm5563, 2022 | 21 | 2022 |
| Enantio-and Diastereodivergent Synthetic Route to Multifarious Cyclitols from D-Xylose via Ring-Closing Metathesis G Luchetti, K Ding, M d’Alarcao, A Kornienko Synthesis 2008 (19), 3142-3147, 2008 | 16 | 2008 |
| Synthesis of Differentially Protected myo-and chiro-Inositols from D-Xylose: Stereoselectivity in Intramolecular SmI2-Promoted Pinacol Reactions G Luchetti, K Ding, A Kornienko, M d’Alarcao Synthesis 2008 (19), 3148-3154, 2008 | 3 | 2008 |
| Cholesterol as a Second Messenger in the Hedgehog Signaling Pathway M Kinnebrew, E Iverson, B Patel, G Pusapati, J Kong, K Johnson, ... The FASEB Journal 35, 2021 | | 2021 |
| Sphingomyelin suppresses Hedgehog signaling by restricting cholesterol accessibility at the ciliary membrane M Kinnebrew, EJ Iverson, BB Patel, GV Pusapati, JH Kong, KA Johnson, ... bioRxiv, 699819, 2019 | | 2019 |
| Regulation of Hedgehog Signaling by Cholesterol G Luchetti Stanford University, 2017 | | 2017 |
| Structural basis for Smoothened regulation by its extracellular domains C Siebold, E Byrne, P Miller, M Sansom, G Hedger, S Newstead, R Sircar, ... Nature 535, 2016 | | 2016 |
| 微生物及免疫學研究所專題討論摘要 G Luchetti, JL Roncaioli, RA Chavez, AF Schubert, EM Kofoed, R Reja, ... | | |
