| PARP Inhibitor Efficacy Depends on CD8+ T-cell Recruitment via Intratumoral STING Pathway Activation in BRCA-Deficient Models of Triple-Negative Breast Cancer C Pantelidou, O Sonzogni, M De Oliveria Taveira, AK Mehta, A Kothari, ... Cancer discovery 9 (6), 722-737, 2019 | 516 | 2019 |
| Class IIa HDAC inhibition reduces breast tumours and metastases through anti-tumour macrophages JL Guerriero, A Sotayo, HE Ponichtera, JA Castrillon, AL Pourzia, ... Nature 543 (7645), 428-432, 2017 | 496 | 2017 |
| Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer AK Mehta, EM Cheney, CA Hartl, C Pantelidou, M Oliwa, JA Castrillon, ... Nature Cancer 2 (1), 66-82, 2021 | 151 | 2021 |
| Comprehensive characterization of protein–protein interactions perturbed by disease mutations F Cheng, J Zhao, Y Wang, W Lu, Z Liu, Y Zhou, WR Martin, R Wang, ... Nature genetics 53 (3), 342-353, 2021 | 143 | 2021 |
| Synergistic immunostimulatory effects and therapeutic benefit of combined histone deacetylase and bromodomain inhibition in non–small cell lung cancer DO Adeegbe, Y Liu, PH Lizotte, Y Kamihara, AR Aref, C Almonte, R Dries, ... Cancer discovery 7 (8), 852-867, 2017 | 138 | 2017 |
| Identification of pathogenic variant enriched regions across genes and gene families E Pérez-Palma, P May, S Iqbal, LM Niestroj, J Du, HO Heyne, ... Genome Research 30 (1), 62-71, 2020 | 61 | 2020 |
| Transcriptomics-based network medicine approach identifies metformin as a repurposable drug for atrial fibrillation JC Lal, C Mao, Y Zhou, SR Gore-Panter, JH Rennison, BS Lovano, ... Cell Reports Medicine 3 (10), 2022 | 25 | 2022 |
| A retrospective analysis of cardiovascular adverse events associated with immune checkpoint inhibitors JC Lal, SA Brown, P Collier, F Cheng Cardio-Oncology 7 (1), 1-10, 2021 | 23 | 2021 |
| Comparing syngeneic and autochthonous models of breast cancer to identify tumor immune components that correlate with response to immunotherapy in breast cancer JC Lal, MG Townsend, AK Mehta, M Oliwa, E Miller, A Sotayo, E Cheney, ... Breast Cancer Research 23, 1-24, 2021 | 16 | 2021 |
| Establishing an interdisciplinary research team for cardio-oncology artificial intelligence informatics precision and health equity SA Brown, R Sparapani, K Osinski, J Zhang, J Blessing, F Cheng, ... American heart journal plus: cardiology research and practice 13, 100094, 2022 | 14 | 2022 |
| Pharmacogenomics for immunotherapy and immune-related cardiotoxicity JA Castrillon, C Eng, F Cheng Human Molecular Genetics 29 (R2), R186-R196, 2020 | 10 | 2020 |
| Team principles for successful interdisciplinary research teams SA Brown, R Sparapani, K Osinski, J Zhang, J Blessing, F Cheng, ... American Heart Journal Plus: Cardiology Research and Practice, 100306, 2023 | 6 | 2023 |
| Pharmacogenomics meets precision cardio-oncology: is there synergistic potential? JK Hockings, JA Castrillon, F Cheng Human Molecular Genetics 29 (R2), R177-R185, 2020 | 4 | 2020 |
| The mutational landscape of cancer's vulnerability to ionizing radiation P Gopal, BD Yard, A Petty, JC Lal, TK Bera, TQ Hoang, AD Buhimschi, ... Clinical Cancer Research 28 (24), 5343-5358, 2022 | 2 | 2022 |
| Deconvoluting cellular neighborhoods in pancreatic ductal adenocarcinoma JC Lal Communications Biology 5 (1), 1099, 2022 | 1 | 2022 |
| Network-based prediction and functional validation of metformin for potential treatment of atrial fibrillation using human inducible pluripotent stem cell-derived atrial-like … JC Lal, Y Zhou, SR Gore-Panter, JH Rennison, J Barnard, ... bioRxiv, 2021.09. 17.460826, 2021 | 1 | 2021 |
| Improving Health Behaviors and Weight Parameters With Motivational Interviewing and the TEEEN Program in an Ethnically and Socioeconomically Diverse Pediatric Population JC Lal, L Margai, HS Zitkovsky, LL Price, S González American Journal of Medicine Open 10, 100042, 2023 | | 2023 |
| Impaired Branched-Chain Amino Acid Catabolism is Associated With Chemotherapy-Induced Heart Failure and Rescued by Metformin F Cheng, J Lal, Y Hou, JD Smith, DR Van Wagoner, PH Collier, ... Circulation 148 (Suppl_1), A15504-A15504, 2023 | | 2023 |
| Artificial Intelligence for Risk Assessment of Cancer Therapy-Related Cardiotoxicity and Precision Cardio-Oncology JC Lal, F Cheng Machine Learning and Deep Learning in Computational Toxicology, 563-578, 2023 | | 2023 |
| Network-Based Multi-Omics Approaches for Precision Cardio-Oncology: Pathobiology, Drug Repurposing and Functional Testing JC Lal Case Western Reserve University, 2023 | | 2023 |
