CFTR modulators: the changing face of cystic fibrosis in the era of precision medicine M Lopes-Pacheco Frontiers in pharmacology 10, 500191, 2020 | 435 | 2020 |
CFTR modulators: shedding light on precision medicine for cystic fibrosis M Lopes-Pacheco Frontiers in pharmacology 7, 210967, 2016 | 206 | 2016 |
Effects of different mesenchymal stromal cell sources and delivery routes in experimental emphysema MA Antunes, SC Abreu, FF Cruz, AC Teixeira, M Lopes-Pacheco, ... Respiratory Research 15, 1-14, 2014 | 166 | 2014 |
Pathogenesis of multiple organ injury in COVID-19 and potential therapeutic strategies M Lopes-Pacheco, PL Silva, FF Cruz, D Battaglini, C Robba, P Pelosi, ... Frontiers in physiology 12, 593223, 2021 | 151 | 2021 |
Laboratory biomarkers for diagnosis and prognosis in COVID-19 D Battaglini, M Lopes-Pacheco, HC Castro-Faria-Neto, P Pelosi, ... Frontiers in immunology 13, 857573, 2022 | 115 | 2022 |
Cell‐based therapy for silicosis M Lopes-Pacheco, E Bandeira, MM Morales Stem cells international 2016 (1), 5091838, 2016 | 111 | 2016 |
Current understanding of the immunosuppressive properties of mesenchymal stromal cells LL de Castro, M Lopes-Pacheco, DJ Weiss, FF Cruz, PRM Rocco Journal of Molecular Medicine 97, 605-618, 2019 | 103 | 2019 |
Dasatinib reduces lung inflammation and fibrosis in acute experimental silicosis FF Cruz, LFB Horta, LA Maia, M Lopes-Pacheco, AB Silva, MM Morales, ... PloS one 11 (1), e0147005, 2016 | 82 | 2016 |
Current understanding of the therapeutic benefits of mesenchymal stem cells in acute respiratory distress syndrome M Lopes-Pacheco, C Robba, PRM Rocco, P Pelosi Cell biology and toxicology 36, 83-102, 2020 | 74 | 2020 |
Mesenchymal stem cells from bone marrow, adipose tissue, and lung tissue differentially mitigate lung and distal organ damage in experimental acute respiratory distress syndrome JD Silva, M Lopes-Pacheco, AHR Paz, FF Cruz, EB Melo, MV de Oliveira, ... Critical care medicine 46 (2), e132-e140, 2018 | 74 | 2018 |
Mesenchymal stromal cells are more effective than their extracellular vesicles at reducing lung injury regardless of acute respiratory distress syndrome etiology JD Silva, LL de Castro, CL Braga, GP Oliveira, SA Trivelin, ... Stem cells international 2019 (1), 8262849, 2019 | 57 | 2019 |
Rescuing trafficking mutants of the ATP-binding cassette protein, ABCA4, with small molecule correctors as a treatment for Stargardt eye disease I Sabirzhanova, ML Pacheco, D Rapino, R Grover, JT Handa, ... Journal of Biological Chemistry 290 (32), 19743-19755, 2015 | 57 | 2015 |
Mesenchymal stromal cell-derived extracellular vesicles in lung diseases: current status and perspectives SC Abreu, M Lopes-Pacheco, DJ Weiss, PRM Rocco Frontiers in Cell and Developmental Biology 9, 600711, 2021 | 55 | 2021 |
Discovery of CFTR modulators for the treatment of cystic fibrosis M Lopes-Pacheco, N Pedemonte, G Veit Expert Opinion on Drug Discovery 16 (8), 897-913, 2021 | 48 | 2021 |
Rescue of NBD2 mutants N1303K and S1235R of CFTR by small-molecule correctors and transcomplementation D Rapino, I Sabirzhanova, M Lopes-Pacheco, R Grover, WB Guggino, ... PloS one 10 (3), e0119796, 2015 | 48 | 2015 |
Serum from asthmatic mice potentiates the therapeutic effects of mesenchymal stromal cells in experimental allergic asthma SC Abreu, DG Xisto, TB Oliveira, NG Blanco, LL Castro, JZ Kitoko, ... Stem cells translational medicine 8 (3), 301-312, 2019 | 47 | 2019 |
Combination of correctors rescue ΔF508-CFTR by reducing its association with Hsp40 and Hsp27 M Lopes-Pacheco, C Boinot, I Sabirzhanova, MM Morales, WB Guggino, ... Journal of Biological Chemistry 290 (42), 25636-25645, 2015 | 45 | 2015 |
Eicosapentaenoic acid potentiates the therapeutic effects of adipose tissue-derived mesenchymal stromal cells on lung and distal organ injury in experimental sepsis JD Silva, M Lopes-Pacheco, LL de Castro, JZ Kitoko, SA Trivelin, ... Stem Cell Research & Therapy 10, 1-16, 2019 | 44 | 2019 |
Eicosapentaenoic acid enhances the effects of mesenchymal stromal cell therapy in experimental allergic asthma SC Abreu, M Lopes-Pacheco, AL Da Silva, DG Xisto, TB De Oliveira, ... Frontiers in Immunology 9, 1147, 2018 | 43 | 2018 |
Combination of correctors rescues CFTR transmembrane-domain mutants by mitigating their interactions with proteostasis M Lopes-Pacheco, C Boinot, I Sabirzhanova, D Rapino, L Cebotaru Cellular Physiology and Biochemistry 41 (6), 2194-2210, 2017 | 42 | 2017 |