FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy RL Begay, CA Tharp, A Martin, SL Graw, G Sinagra, D Miani, ME Sweet, ... JACC: Basic to Translational Science 1 (5), 344-359, 2016 | 112 | 2016 |
The giant protein titin’s role in cardiomyopathy: genetic, transcriptional, and post-translational modifications of TTN and their contribution to cardiac disease CA Tharp, ME Haywood, O Sbaizero, MRG Taylor, L Mestroni Frontiers in physiology 10, 1436, 2019 | 104 | 2019 |
Therapeutic targets for cardiac fibrosis: from old school to next-gen JG Travers, CA Tharp, M Rubino, TA McKinsey The Journal of clinical investigation 132 (5), 2022 | 74 | 2022 |
The sarcomeric spring protein titin: biophysical properties, molecular mechanisms, and genetic mutations associated with heart failure and cardiomyopathy R Eldemire, CA Tharp, MRG Taylor, O Sbaizero, L Mestroni Current cardiology reports 23, 1-9, 2021 | 26 | 2021 |
Modifications of titin contribute to the progression of cardiomyopathy and represent a therapeutic target for treatment of heart failure C Tharp, L Mestroni, M Taylor Journal of Clinical Medicine 9 (9), 2770, 2020 | 25 | 2020 |
Reversible lysine fatty acylation of an anchoring protein mediates adipocyte adrenergic signaling RA Bagchi, EL Robinson, T Hu, J Cao, JY Hong, CA Tharp, H Qasim, ... Proceedings of the National Academy of Sciences 119 (7), e2119678119, 2022 | 13 | 2022 |
FLNC gene splice mutations cause dilated cardiomyopathy. JACC Basic Transl Sci 1: 344–359 RL Begay, CA Tharp, A Martin, SL Graw, G Sinagra, D Miani, ME Sweet, ... | 5 | 2016 |
FLNC gene splice mutation causes dilated cardiomyopathy in two families RL Begay, A Martin, SL Graw, DB Slavov, CA Tharp, M Sweet, F Brun, ... Circulation 130 (suppl_2), A11923-A11923, 2014 | 2 | 2014 |
Molecular Genetics of Dilated Cardiomyopathy L Mestroni, CA Tharp, ME Sweet, SL Graw, MRG Taylor eLS, 2014 | 2 | 2014 |
Gravi-D peptide disrupts HDAC11 association with an AKAP to stimulate adipocyte thermogenic signaling EL Robinson, CA Tharp, RA Bagchi, TA McKinsey The Journal of Clinical Investigation 134 (9), 2024 | | 2024 |
Atypical Wenckebach without grouped beating due to dual AV nodal conduction JM Cunningham, A Mackey, C Tharp Journal of Electrocardiology 82, 83-85, 2024 | | 2024 |
Tissue is the issue: Endomyocardial biopsies to elucidate molecular mechanisms and tailor therapy for HFpEF CA Tharp, TA McKinsey Journal of Molecular and Cellular Cardiology 169, 111-112, 2022 | | 2022 |
ASPIRIN-MEDIATED LYSINE ACETYLATION ALTERS SARCOMERIC MECHANICAL PROPERTIES IN CARDIOMYOCYTES C Tharp, KC Woulfe, T McKinsey Journal of the American College of Cardiology 79 (9_Supplement), 284-284, 2022 | | 2022 |
one of the main causes of heart failure and heart transplant. Titin is a giant protein, and the mechanisms causing the disease are both complex and still incompletely … CA Tharp, ME Haywood, O Sbaizero, MRG Taylor, L Mestroni Recent Advances on Myocardium Physiology, 9, 2021 | | 2021 |
Characterization of Arrhythmogenic Dilated Cardiomyopathy Caused by Novel Filamin C Splice Variant in a Zebrafish Model RL Begay, TJ Rowland, CA Tharp, A Martin, SL Graw, G Sinagra, D Miani, ... Circulation Research 117 (suppl_1), A194-A194, 2015 | | 2015 |