Structure, function, and inhibition of chemokines EJ Fernandez, E Lolis Annual review of pharmacology and toxicology 42 (1), 469-499, 2002 | 926 | 2002 |
Crystal structure of chemically synthesized [N33A] stromal cell-derived factor 1α, a potent ligand for the HIV-1 “fusin” coreceptor C Dealwis, EJ Fernandez, DA Thompson, RJ Simon, MA Siani, E Lolis Proceedings of the National Academy of Sciences 95 (12), 6941-6946, 1998 | 219 | 1998 |
Carbohydrate binding, quaternary structure and a novel hydrophobic binding site in two legume lectin oligomers fromDolichos biflorus TW Hamelryck, R Loris, J Bouckaert, MH Dao-Thi, G Strecker, A Imberty, ... Journal of molecular biology 286 (4), 1161-1177, 1999 | 166 | 1999 |
Structure of the murine constitutive androstane receptor complexed to androstenol: a molecular basis for inverse agonism L Shan, J Vincent, JS Brunzelle, I Dussault, M Lin, I Ianculescu, ... Molecular cell 16 (6), 907-917, 2004 | 142 | 2004 |
Orally bioavailable androgen receptor degrader, potential next-generation therapeutic for enzalutamide-resistant prostate cancer S Ponnusamy, Y He, DJ Hwang, T Thiyagarajan, R Houtman, ... Clinical Cancer Research 25 (22), 6764-6780, 2019 | 57 | 2019 |
Comparison of the Structure of vMIP-II with Eotaxin-1, RANTES, and MCP-3 Suggests a Unique Mechanism for CCR3 Activation, EJ Fernandez, J Wilken, DA Thompson, SC Peiper, E Lolis Biochemistry 39 (42), 12837-12844, 2000 | 51 | 2000 |
Hepatic stellate cell activation: A source for bioactive lipids. BWS Shmarakov IO, Jiang H, Liu J, Fernandez EJ Biochim Biophys Acta Mol Cell Biol Lipids. 1864 (5), 629-642, 2019 | 44* | 2019 |
Structural basis for negative cooperativity within agonist-bound TR: RXR heterodimers BDK Putcha, E Wright, JS Brunzelle, EJ Fernandez Proceedings of the National Academy of Sciences 109 (16), 6084-6087, 2012 | 43 | 2012 |
Mapping allostery through computational glycine scanning and correlation analysis of Residue–Residue contacts QR Johnson, RJ Lindsay, RB Nellas, EJ Fernandez, T Shen Biochemistry 54 (7), 1534-1541, 2015 | 42 | 2015 |
Direct interdomain interactions can mediate allosterism in the thyroid receptor BDK Putcha, EJ Fernandez Journal of Biological Chemistry 284 (34), 22517-22524, 2009 | 40 | 2009 |
Thermodynamic Characterization of the Interaction between CAR− RXR and SRC-1 Peptide by Isothermal Titration Calorimetry E Wright, J Vincent, EJ Fernandez Biochemistry 46 (3), 862-870, 2007 | 32 | 2007 |
Crystal structure of Lysβ182-Lysβ282 crosslinked hemoglobin: A possible allosteric intermediate EJ Fernandez, C Abad-Zapatero, KW Olsen Journal of Molecular Biology 296 (5), 1245-1256, 2000 | 32 | 2000 |
Helix 11 dynamics is critical for constitutive androstane receptor activity E Wright, SA Busby, S Wisecarver, J Vincent, PR Griffin, EJ Fernandez Structure 19 (1), 37-44, 2011 | 31 | 2011 |
Allosteric pathways in nuclear receptors—Potential targets for drug design EJ Fernandez Pharmacology & therapeutics 183, 152-159, 2018 | 29 | 2018 |
Lrg1 Regulates β (1,3)-Glucan Masking in Candida albicans through the Cek1 MAP Kinase Pathway RTB Chen Tian, Wagner AS, Tams RN, Eyer James E, Kauffman Sarah J, Gann ER ... MBio 10 (5), 2019 | 27 | 2019 |
The promiscuity of allosteric regulation of nuclear receptors by retinoid X receptor AK Clark, JH Wilder, AW Grayson, QR Johnson, RJ Lindsay, RB Nellas, ... The Journal of Physical Chemistry B 120 (33), 8338-8345, 2016 | 23 | 2016 |
Accessibility of selenomethionine proteins by total chemical synthesis: structural studies of human herpesvirus-8 MIP-II W Shao, E Fernandez, J Wilken, DA Thompson, MA Siani, J West, E Lolis, ... FEBS letters 441 (1), 77-82, 1998 | 18 | 1998 |
Agonist ligands mediate the transcriptional response of nuclear receptor heterodimers through distinct stoichiometric assemblies with coactivators MR Pavlin, JS Brunzelle, EJ Fernandez Journal of Biological Chemistry 289 (36), 24771-24778, 2014 | 16 | 2014 |
Structural studies of chemokines that inhibit HIV-1 entry. EJ Fernandez, E Lolis Antiviral chemistry & chemotherapy 12, 43-49, 2001 | 16 | 2001 |
CCR2 and CCR5 receptor‐binding properties of herpesvirus‐8 vMIP‐II based on sequence analysis and its solution structure W Shao, E Fernandez, A Sachpatzidis, J Wilken, DA Thompson, ... European Journal of Biochemistry 268 (10), 2948-2959, 2001 | 15 | 2001 |