Site-specific integration and tailoring of cassette design for sustainable gene transfer A Lombardo, D Cesana*, P Genovese*, B Di Stefano*, E Provasi*, ... Nature methods 8 (10), 861, 2011 | 394 | 2011 |
Polycomb complexes in stem cells and embryonic development L Aloia, B Di Stefano, L Di Croce Development 140 (12), 2525-2534, 2013 | 354 | 2013 |
Transcription factors orchestrate dynamic interplay between genome topology and gene regulation during cell reprogramming R Stadhouders, E Vidal, F Serra, B Di Stefano, F Le Dily, J Quilez, ... Nature genetics 50 (2), 238-249, 2018 | 340 | 2018 |
Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells J Choi, AJ Huebner, K Clement, RM Walsh, A Savol, K Lin, H Gu, ... Nature 548 (7666), 219-223, 2017 | 255 | 2017 |
C/EBPα poises B cells for rapid reprogramming into induced pluripotent stem cells B Di Stefano, JL Sardina, C van Oevelen, S Collombet, EM Kallin, ... Nature 506 (7487), 235-239, 2014 | 246 | 2014 |
Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses C Verpelli, E Dvoretskova, C Vicidomini, F Rossi, M Chiappalone, ... Journal of Biological Chemistry 286 (40), 34839-34850, 2011 | 232 | 2011 |
Transcription factors drive Tet2-mediated enhancer demethylation to reprogram cell fate JL Sardina, S Collombet, TV Tian, A Gómez, B Di Stefano, C Berenguer, ... Cell stem cell 23 (5), 727-741. e9, 2018 | 229 | 2018 |
Cell-of-origin-specific 3D genome structure acquired during somatic cell reprogramming PHL Krijger*, B Di Stefano*, E de Wit*, F Limone, C Van Oevelen, ... Cell Stem Cell 18 (5), 597-610, 2016 | 213 | 2016 |
Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling J Brumbaugh*, B Di Stefano*, X Wang, M Borkent, E Forouzmand, ... Cell 172 (1-2), 106-120. e21, 2018 | 168 | 2018 |
Leptin/HER2 crosstalk in breast cancer: in vitro study and preliminary in vivoanalysis E Fiorio, A Mercanti, M Terrasi, R Micciolo, A Remo, A Auriemma, ... BMC cancer 8, 1-11, 2008 | 133 | 2008 |
Logical modeling of lymphoid and myeloid cell specification and transdifferentiation S Collombet, C Van Oevelen, JL Sardina Ortega, W Abou-Jaoudé, ... Proceedings of the National Academy of Sciences 114 (23), 5792-5799, 2017 | 131 | 2017 |
C/EBPα creates elite cells for iPSC reprogramming by upregulating Klf4 and increasing the levels of Lsd1 and Brd4 B Di Stefano*, S Collombet*, JS Jakobsen*, M Wierer, JL Sardina, ... Nature cell biology 18 (4), 371, 2016 | 119 | 2016 |
The RNA helicase DDX6 controls cellular plasticity by modulating P-body homeostasis B Di Stefano, EC Luo, C Haggerty, S Aigner, J Charlton, J Brumbaugh, ... Cell stem cell 25 (5), 622-638. e13, 2019 | 100 | 2019 |
Direct Reprogramming of Mouse Fibroblasts into Functional Skeletal Muscle Progenitors O Bar-Nur*, MFM Gerli*, B Di Stefano, AE Almada, A Galvin, A Coffey, ... Stem cell reports 10 (5), 1505-1521, 2018 | 89 | 2018 |
Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells. B Di Stefano, M Ueda, S Sabri, J Brumbaugh, AJ Huebner, A Sahakyan, ... Nature methods 15 (9), 732-740, 2018 | 85 | 2018 |
Single cell RNA-seq identifies the origins of heterogeneity in efficient cell transdifferentiation and reprogramming M Francesconi*, B Di Stefano*, C Berenguer, L de Andrés-Aguayo, ... eLife 8, e41627, 2019 | 62 | 2019 |
Reprogramming human B cells into induced pluripotent stem cells and its enhancement by C/EBPα C Bueno*, JL Sardina*, B Di Stefano, D Romero-Moya, A Munoz-Lopez, ... Leukemia 30 (3), 674, 2016 | 56 | 2016 |
Reprogramming: identifying the mechanisms that safeguard cell identity J Brumbaugh, B Di Stefano, K Hochedlinger Development 146 (23), dev182170, 2019 | 53 | 2019 |
Active DNA demethylation promotes cell fate specification and the DNA damage response D Wang, W Wu, E Callen, R Pavani, N Zolnerowich, S Kodali, D Zong, ... Science 378 (6623), 983-989, 2022 | 51 | 2022 |
Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo J Brumbaugh, IS Kim, F Ji, AJ Huebner, B Di Stefano, BA Schwarz, ... Nature cell biology 21 (11), 1449-1461, 2019 | 50 | 2019 |